Timeline

Carmen Buchrieser
Head of Structure
20 May 2019
publication

Intracellular parasitism, the driving force of evolution of Legionella pneumophila and the genus Legionella.

Read more
08 Mar 2019
publication

A Ca-regulated deAMPylation switch in human and bacterial FIC proteins

Read more
20 Feb 2019
event

130 Years of Institut Pasteur: Celebrating Science

Read more
31 Jan 2019
news

How human pathogens may emerge from the environment

Read more
18 Jan 2019
publication

More than 18,000 effectors in the genus genome provide multiple, independent combinations for replication in human cells

Read more
08 Jan 2019
publication

The pleotropic Legionella transcription factor LvbR links the Lqs and c-di-GMP regulatory networks to control biofilm architecture and virulence

Read more
01 Jan 2019
publication

Sorting of Phagocytic Cells Infected with Legionella pneumophila

Read more
01 Jan 2019
publication

Mitochondrial Dynamics and Activity in Legionella-Infected Cells

Read more
01 Jan 2019
publication

Analysis of the Pulmonary Microbiome Composition of Legionella pneumophila-Infected Patients

Read more
06 Dec 2018
news

Conferences organized by the Scientific Council – 2019

Read more
18 May 2018
publication

Targeting of RNA Polymerase II by a nuclear Legionella pneumophila Dot/Icm effector SnpL

Read more
04 May 2018
publication

The Legionella pneumophila Methyltransferase RomA Methylates Also Non-histone Proteins during Infection

Read more
14 Apr 2018
publication

Metabolic reprogramming of host cells upon bacterial infection: Why shift to a Warburg-like metabolism?

Read more
01 Feb 2018
publication

Editorial overview: Host-pathogen interactions shaped through evolutionary and regulatory processes

Read more
30 Jan 2018
publication

Legionella Effectors Explored with INSeq: New Functional Insights

Read more
19 Jan 2018
publication

The Life Cycle of L. pneumophila: Cellular Differentiation Is Linked to Virulence and Metabolism

Read more
14 Dec 2017
news

Conferences organized by the Scientific Council – 2018

Read more
07 Nov 2017
publication

Legionella pneumophila CsrA regulates a metabolic switch from amino acid to glycerolipid metabolism.

Read more
06 Sep 2017
publication

Manipulation of Autophagy by Bacterial Pathogens Impacts Host Immunity

Read more
31 Aug 2017
publication

Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages

Read more
26 Jun 2017
publication

Dynamics and impact of homologous recombination on the evolution of Legionella pneumophila

Read more
23 May 2017
news

THE 9TH INTERNATIONAL CONFERENCE ON LEGIONELLA

Read more
23 May 2017
event

“A matter of fat: bioactive lipids at the host-mycobacteria interface” – Caroline Demangel

Read more
14 Apr 2017
event

« Joint analysis of multiple phenotypes using GWAS summary statistics» by Hugues ASCHARD

Read more
13 Apr 2017
event

“Lymphocyte development and lineage commitment in the embryo” by Ana Cumano

Read more
06 Apr 2017
event

ETOX18 – European Workshop on Bacterial Protein Toxins

Read more
06 Apr 2017
event

EMBO Conference on Hijacking host signalling and epigenetic mimicry during infections

Read more
23 Mar 2017
event

“Vascular colonization by Neisseria meningitidis” by Guillaume Duménil

Read more
17 Feb 2017
publication

The Legionella pneumophila genome evolved to accommodate multiple regulatory mechanisms controlled by the CsrA-system

Read more
10 Jan 2017
publication

A Unique cis-Encoded Small Noncoding RNA Is Regulating Legionella pneumophila Hfq Expression in a Life Cycle-Dependent Manner

Read more
01 Jan 2017
publication

Biological Diversity and Evolution of Type IV Secretion Systems

Read more
27 Dec 2016
publication

MAMs are attractive targets for bacterial repurposing of the host cell: MAM-functions might be key for undermining an infected cell

Read more
08 Dec 2016
publication

Legionella longbeachae is immunologically silent and highly virulent in vivo

Read more
30 Nov 2016
publication

Rapid detection and evolutionary analysis of Legionella pneumophila serogroup 1 sequence type 47

Read more
23 Sep 2016
publication

Multiple major disease-associated clones of Legionella pneumophila have emerged recently and independently

Read more
18 May 2016
publication

Legionella pneumophila restrains autophagy by modulating the host’s sphingolipid metabolism

Read more
13 May 2016
publication

Molecular epidemiology, phylogeny and evolution of Legionella

Read more
21 Mar 2016
publication

Environmental treasures: co-isolation of the first marine Chlamydiae and its protozoan host

Read more
03 Mar 2016
publication

Modulation of Host Autophagy during Bacterial Infection: Sabotaging Host Munitions for Pathogen Nutrition

Read more
03 Feb 2016
news

Legionella pneumophila: identification of a new strategy to counteract the antibacterial response of the host cell

Read more
01 Feb 2016
publication

The α-hydroxyketone LAI-1 regulates motility, Lqs-dependent phosphorylation signalling and gene expression of Legionella pneumophila

Read more
01 Feb 2016
publication

Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy

Read more
01 Jan 2016
publication

Targeting of host organelles by pathogenic bacteria: a sophisticated subversion strategy

Read more
02 Dec 2015
event

EMBO Conference Tuberculosis 2016

Read more
25 Sep 2015
publication

Contractile actin cables induced by Bacillus anthracis lethal toxin depend on the histone acetylation machinery

Read more
08 Sep 2015
event

EMBO Conference ‘International Symposium on Problems of Listeriosis’

Read more
01 Aug 2015
publication

Bacterial remodelling of the host epigenome: functional role and evolution of effectors methylating host histones

Read more
10 Jun 2015
project

Molecular, genetic and cellular basis of the infection by Legionella

Read more
11 May 2015
team

Biology Of Intracellular Bacteria

Read more
01 May 2015
publication

Small RNAs, 5′ UTR elements and RNA-binding proteins in intracellular bacteria: impact on metabolism and virulence

Read more
28 Jan 2015
publication

Corrigendum: Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline

Read more
15 Sep 2014
publication

IroT/mavN, a new iron-regulated gene involved in Legionella pneumophila virulence against amoebae and macrophages

Read more
04 Aug 2014
publication

Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline

Read more
08 Jul 2014
publication

Legionella pneumophila type IV effectors hijack the transcription and translation machinery of the host cell

Read more
01 Jan 2014
publication

Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires’ disease

Read more
18 Oct 2013
publication

[Host epigenetic targeting by Legionella pneumophila]

Read more
19 Aug 2013
publication

The Legionella pneumophila kai operon is implicated in stress response and confers fitness in competitive environments

Read more
11 Jul 2013
publication

Human single-chain urokinase is activated by the omptins PgtE of Salmonella enterica and Pla of Yersinia pestis despite mutations of active site residues

Read more
01 Jun 2013
publication

Genome dynamics in Legionella: the basis of versatility and adaptation to intracellular replication

Read more
17 Apr 2013
publication

Legionella pneumophila effector RomA uniquely modifies host chromatin to repress gene expression and promote intracellular bacterial replication

Read more
14 Jan 2013
publication

Nicotinic acid modulates Legionella pneumophila gene expression and induces virulence traits

Read more
01 Jan 2013
publication

From amoeba to macrophages: exploring the molecular mechanisms of Legionella pneumophila infection in both hosts

Read more
01 Jan 2013
publication

Co-immunoprecipitation: protein-RNA and protein-DNA interaction

Read more
01 Jan 2013
publication

cDNA library construction for next-generation sequencing to determine the transcriptional landscape of Legionella pneumophila

Read more
01 Jan 2013
publication

Induction of competence for natural transformation in Legionella pneumophila and exploitation for mutant construction

Read more
04 Oct 2012
publication

The Legionella pneumophila orphan sensor kinase LqsT regulates competence and pathogen-host interactions as a component of the LAI-1 circuit

Read more
15 Jul 2012
publication

Characterization of an acetyltransferase that detoxifies aromatic chemicals in Legionella pneumophila

Read more
24 Apr 2012
publication

Comparative genomics and transcriptomics of lineages I, II, and III strains of Listeria monocytogenes

Read more
01 Apr 2012
publication

Deep sequencing defines the transcriptional map of L. pneumophila and identifies growth phase-dependent regulated ncRNAs implicated in virulence

Read more
01 Mar 2012
publication

Post-translational modifications of host proteins by Legionella pneumophila: a sophisticated survival strategy

Read more
27 Nov 2011
publication

Legionella pneumophila transcriptional response to chlorine treatment

Read more
01 Nov 2011
publication

Extensive recombination events and horizontal gene transfer shaped the Legionella pneumophila genomes

Read more
28 Oct 2011
publication

Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions

Read more
23 Oct 2011
publication

Population variation in NAIP functional copy number confers increased cell death upon Legionella pneumophila infection

Read more
12 Oct 2011
publication

Legionella: from protozoa to humans

Read more
20 Dec 2010
publication

Fatty acid composition modulates sensitivity of Legionella pneumophila to warnericin RK, an antimicrobial peptide

Read more
06 Dec 2010
publication

Circadian clock proteins in prokaryotes: hidden rhythms?

Read more
20 Oct 2010
publication

GamA is a eukaryotic-like glucoamylase responsible for glycogen- and starch-degrading activity of Legionella pneumophila

Read more
26 May 2010
publication

The origins of eukaryotic-like proteins in Legionella pneumophila

Read more
04 May 2010
publication

Isotopologue profiling of Legionella pneumophila: role of serine and glucose as carbon substrates

Read more
29 Mar 2010
publication

The Legionella pneumophila LetA/LetS two-component system exhibits rheostat-like behavior

Read more
25 Mar 2010
publication

The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication

Read more
28 Feb 2010
publication

Distinct roles of ppGpp and DksA in Legionella pneumophila differentiation

Read more
19 Feb 2010
publication

Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires’ disease

Read more
10 Feb 2010
publication

Update on Legionnaires’ disease: pathogenesis, epidemiology, detection and control

Read more
09 Feb 2010
publication

The autoinducer synthase LqsA and putative sensor kinase LqsS regulate phagocyte interactions, extracellular filaments and a genomic island of Legionella pneumophila

Read more
13 Nov 2009
publication

Listeria rocourtiae sp. nov

Read more
13 Nov 2009
publication

Control of flagellar gene regulation in Legionella pneumophila and its relation to growth phase

Read more
13 Nov 2009
publication

A trans-acting riboswitch controls expression of the virulence regulator PrfA in Listeria monocytogenes

Read more
09 Oct 2009
publication

NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis

Read more
01 Oct 2009
publication

Frank Kunst, 1943-2009

Read more
24 Sep 2009
publication

From functional genomics to systems (micro)biology

Read more
01 Aug 2009
publication

Molecular mimicry: an important virulence strategy employed by Legionella pneumophila to subvert host functions

Read more
23 Jun 2009
publication

Listeria monocytogenes L-forms respond to cell wall deficiency by modifying gene expression and the mode of division

Read more
29 May 2009
publication

In vivo transcriptional profiling of Listeria monocytogenes and mutagenesis identify new virulence factors involved in infection

Read more
01 May 2009
publication

Two small ncRNAs jointly govern virulence and transmission in Legionella pneumophila

Read more
01 Apr 2009
publication

Genome sequence of Vibrio splendidus: an abundant planctonic marine species with a large genotypic diversity

Read more
19 Sep 2008
publication

Synergistic contribution of the Legionella pneumophila lqs genes to pathogen-host interactions

Read more
21 Apr 2008
publication

Significant role for ladC in initiation of Legionella pneumophila infection

Read more
14 Apr 2008
publication

The Legionella autoinducer synthase LqsA produces an alpha-hydroxyketone signaling molecule

Read more
06 Feb 2008
publication

Multigenome analysis identifies a worldwide distributed epidemic Legionella pneumophila clone that emerged within a highly diverse species

Read more
18 Jan 2008
publication

Pathogenomics: an updated European Research Agenda

Read more
01 Jan 2008
publication

Transcriptional profiling of Legionella pneumophila biofilm cells and the influence of iron on biofilm formation

Read more
17 Aug 2007
publication

Comparative transcriptome analysis of Listeria monocytogenes strains of the two major lineages reveals differences in virulence, cell wall, and stress response

Read more
05 Jul 2007
publication

The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA

Read more
21 May 2007
publication

Legionella pneumophila adaptation to intracellular life and the host response: clues from genomics and transcriptomics

Read more
07 May 2007
publication

Pathogenomics of Listeria spp

Read more
06 May 2007
publication

Biodiversity of the species Listeria monocytogenes and the genus Listeria

Read more
30 Apr 2007
publication

Legionella pathogenicity: genome structure, regulatory networks and the host cell response

Read more
12 Jan 2007
publication

The presence of the internalin gene in natural atypically hemolytic Listeria innocua strains suggests descent from L. monocytogenes

Read more
01 Jan 2007
publication

Bringing the genome of Legionella pneumophila to life (book chapter)

Read more
26 Dec 2006
publication

Genetic diversity of Listeria monocytogenes recovered from infected persons and pork, seafood and dairy products on retail sale in France during 2000 and 2001

Read more
01 Dec 2006
publication

Growth-phase-dependent mobility of the lvh-encoding region in Legionella pneumophila strain Paris

Read more
16 Oct 2006
publication

Specific regions of genome plasticity and genetic diversity of the commensal Escherichia coli A0 34/86

Read more
26 Sep 2006
publication

Use of DNA arrays for the analysis of outbreak-related strains of Listeria monocytogenes

Read more
15 Aug 2006
publication

How to become a uropathogen: comparative genomic analysis of extraintestinal pathogenic Escherichia coli strains

Read more
11 Aug 2006
publication

Escherichia coli induces DNA double-strand breaks in eukaryotic cells

Read more
01 Aug 2006
publication

Virulence strategies for infecting phagocytes deduced from the in vivo transcriptional program of Legionella pneumophila

Read more
19 Jan 2006
publication

Genomic diversity and evolution within the species Streptococcus agalactiae

Read more
06 Jan 2006
publication

Adaptation of Legionella pneumophila to the host environment: role of protein secretion, effectors and eukaryotic-like proteins

Read more
01 May 2005
publication

[What do we learn from the genome of Legionella pneumophila?]

Read more
01 Feb 2005
publication

Characterization of the flexible genome complement of the commensal Escherichia coli strain A0 34/86 (O83 : K24 : H31)

Read more
01 Jan 2005
publication

How seryl-phosphorylated HPr inhibits PrfA, a transcription activator of Listeria monocytogenes virulence genes

Read more
03 Oct 2004
publication

Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity

Read more
01 Oct 2004
publication

The pathogenicity island-associated K15 capsule determinant exhibits a novel genetic structure and correlates with virulence in uropathogenic Escherichia coli strain 536

Read more
01 Aug 2004
publication

Differentiation of the major Listeria monocytogenes serovars by multiplex PCR

Read more
01 May 2004
publication

Global analysis of gene expression in an rpoN mutant of Listeria monocytogenes

Read more
01 May 2004
publication

DNA macroarray for identification and typing of Staphylococcus aureus isolates

Read more
01 Apr 2004
publication

Pathogenomics of mobile genetic elements of toxigenic bacteria

Read more
01 Feb 2004
publication

Macro-array and bioinformatic analyses reveal mycobacterial ‘core’ genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex

Read more
01 Feb 2004
publication

New aspects regarding evolution and virulence of Listeria monocytogenes revealed by comparative genomics and DNA arrays

Read more
05 Oct 2003
publication

The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens

Read more
01 Apr 2003
publication

Comparison of the genome sequences of Listeria monocytogenes and Listeria innocua: clues for evolution and pathogenicity

Read more
01 Mar 2003
publication

Transcriptome analysis of Listeria monocytogenes identifies three groups of genes differently regulated by PrfA

Read more
01 Mar 2003
publication

Analysis of genome plasticity in pathogenic and commensal Escherichia coli isolates by use of DNA arrays

Read more
01 Sep 2002
publication

Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease

Read more
01 Aug 2002
publication

Listeria monocytogenes bile salt hydrolase is a PrfA-regulated virulence factor involved in the intestinal and hepatic phases of listeriosis

Read more