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© Carmen Buchrieser, Marie-Christine Prevost
Legionella pneumophila et son flagelle, bactérie responsable de pneumopathie aigue grave. Bactérie de l'environnement , l'émergence récente de cette maladie s'explique par son affinité pour les systèmes modernes d'alimentation en eau comme les tours de refroidissement. Image colorisée.
Publication : International journal of medical microbiology : IJMM

Use of DNA arrays for the analysis of outbreak-related strains of Listeria monocytogenes

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in International journal of medical microbiology : IJMM - 26 Sep 2006

Doumith M, Jacquet C, Goulet V, Oggioni C, Van Loock F, Buchrieser C, Martin P

Link to Pubmed [PMID] – 17002895

Int. J. Med. Microbiol. 2006 Dec;296(8):559-62

We evaluated the discriminative power and usefulness of the DNA array technology as compared to DNA macrorestriction pattern analysis for monitoring epidemiologically related clusters of Listeria monocytogenes strains that differ slightly in DNA macrorestriction patterns. We show that this approach allows clarifying the genetic basis of the pattern variations. In the reported outbreak, the differences were due to phage excision, showing the power of this technique in epidemiological studies.