Timeline

Mariette Matondo

Head of Structure

20 Jun 2022

publication

NAD kinase promotes Staphylococcus aureus pathogenesis by supporting production of virulence factors and protective enzymes.

20 May 2022

publication

RNase E and HupB dynamics foster mycobacterial cell homeostasis and fitness.

04 Apr 2022

project

TheraEPI

16 Mar 2022

publication

Experimental evolution links post-transcriptional regulation to Leishmania fitness gain.

01 Feb 2022

project

Phenotypic adaptation to antibiotics: t/rRNA modifications

05 Oct 2021

publication

Listeriolysin S: A bacteriocin from Listeria monocytogenes that induces membrane permeabilization in a contact-dependent manner.

10 Sep 2021

news

New Highlighted publication: “Cryptococcus extracellular vesicles properties and their use as vaccine platforms”, Juliana Rizzo et al. JEV, 2021, RNA Biology of Fungal Pathogen team

01 Aug 2021

publication

Cryptococcus extracellular vesicles properties and their use as vaccine platforms.

19 May 2021

publication

Quality standards in proteomics research facilities: Common standards and quality procedures are essential for proteomics facilities and their users.

18 May 2021

publication

Ser/Thr Kinase-Dependent Phosphorylation of the Peptidoglycan Hydrolase CwlA Controls Its Export and Modulates Cell Division in Clostridioides difficile.

24 Apr 2021

publication

RNase R is associated in a functional complex with the RhpA DEAD-box RNA helicase in Helicobacter pylori.

27 Jan 2021

publication

Proteomic Analysis Uncovers Measles Virus Protein C Interaction with p65/iASPP Protein Complex.

13 Jan 2021

publication

Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein.

12 Jan 2021

project

Insights into amebiasis using a human 3D-intestinal model (ANR-14-IFEC-0001-02)

01 Jan 2021

publication

CYP450 core involvement in multiple resistance strains of Aedes aegypti from French Guiana highlighted by proteomics, molecular and biochemical studies.

01 Jan 2021

publication

Proteomic Analysis of Humoral Immune Components in Bronchoalveolar Lavage of Patients Infected or Colonized by Aspergillus fumigatus.

23 Dec 2020

publication

Mass-spectrometry analysis of the human pineal proteome during night and day and in autism.

10 Nov 2020

software

ProteoCombiner

10 Nov 2020

project

EPIC-XS: European Proteomics Infrastructure Consortium providing access

09 Nov 2020

publication

ProteoCombiner: integrating bottom-up with top-down proteomics data for improved proteoform assessment.

18 Aug 2020

publication

Phosphorylation-Dependent Assembly of a 14-3-3 Mediated Signaling Complex during Red Blood Cell Invasion by Plasmodium falciparum Merozoites.

12 Aug 2020

publication

Characterization of Extracellular Vesicles Produced by Aspergillus fumigatus Protoplasts.

01 Aug 2020

publication

Insights into amebiasis using a human 3D-intestinal model.

01 Aug 2020

publication

Shigella hijacks the exocyst to cluster macropinosomes for efficient vacuolar escape.

01 Aug 2020

publication

Differentiation-dependent susceptibility of human muscle cells to Zika virus infection.

02 Jun 2020

publication

Human Immune Response Triggered by Entamoeba histolytica in a 3D-Intestinal Model

22 Apr 2020

publication

The Flemmingsome reveals an ESCRT-to-membrane coupling via ALIX/syntenin/syndecan-4 required for completion of cytokinesis.

22 Apr 2020

publication

The Flemmingsome reveals an ESCRT-to-membrane coupling via ALIX/syntenin/syndecan-4 required for completion of cytokinesis.

15 Apr 2020

publication

Infection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis in epithelial cells.

12 Mar 2020

publication

Impact of the gut microbiota on the m6A epitranscriptome of mouse cecum and liver.

20 Feb 2020

publication

The transpeptidase PBP2 governs initial localization and activity of the major cell-wall synthesis machinery in E. coli.

04 Feb 2020

publication

Listeria monocytogenes Exploits Mitochondrial Contact Site and Cristae Organizing System Complex Subunit Mic10 To Promote Mitochondrial Fragmentation and Cellular Infection.

06 Jan 2020

publication

Class-A penicillin binding proteins do not contribute to cell shape but repair cell-wall defects

06 Jan 2020

publication

Class-A penicillin binding proteins do not contribute to cell shape but repair cell-wall defects.

01 Jan 2020

publication

Comparison of a human neuronal model proteome upon Japanese encephalitis or West Nile Virus infection and potential role of mosquito saliva in neuropathogenesis.

17 Dec 2019

publication

Dynamic Growth and Shrinkage of the Salmonella-Containing Vacuole Determines the Intracellular Pathogen Niche.

01 Dec 2019

publication

Assembly and disassembly of Aspergillus fumigatus conidial rodlets

01 Dec 2019

publication

Assembly and disassembly of Aspergillus fumigatus conidial rodlets.

12 Nov 2019

tool

Single Cell Proteomics

08 Oct 2019

news

Proteomics Platform satisfaction Survey 2019

13 Sep 2019

project

Landscape of protein ubiquitylation during infection by CNF1-producing uropathogenic E. coli

12 Sep 2019

publication

Cell-wall synthases contribute to bacterial cell-envelope integrity by actively repairing defects

23 Jul 2019

publication

The Ser/Thr Kinase PrkC Participates in Cell Wall Homeostasis and Antimicrobial Resistance in Clostridium difficile.

02 Jul 2019

publication

RadD Contributes to R-Loop Avoidance in Sub-MIC Tobramycin.

01 Jul 2019

publication

Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype.

21 Jun 2019

publication

Post-translational acylation controls the folding and functions of the CyaA RTX toxin.

01 May 2019

publication

The puzzling construction of the conidial outer layer of Aspergillus fumigatus.

06 Mar 2019

publication

Assembly and disassembly of Aspergillus fumigatus conidial rodlets

21 Feb 2019

publication

CotL, a new morphogenetic spore coat protein of Clostridium difficile.

13 Feb 2019

publication

The Adenylate Cyclase (CyaA) Toxin from Bordetella pertussis Has No Detectable Phospholipase A (PLA) Activity In Vitro.

11 Feb 2019

event

MicroOmiX : Enabling droplet microfluidics technologies

10 Oct 2018

project

Role of tubulin glutamylation in flagellum construction (TUBGLUFLA)

24 Apr 2018

publication

Infection Reveals a Modification of SIRT2 Critical for Chromatin Association.

19 Apr 2018

publication

MUB40 Binds to Lactoferrin and Stands as a Specific Neutrophil Marker.

26 Mar 2018

publication

Proteomic analysis of plasma extracellular vesicles reveals mitochondrial stress upon HTLV-1 infection.

26 Sep 2017

publication

Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates.

30 Jun 2017

publication

Outer Membrane Proteome of Veillonella parvula: A Diderm Firmicute of the Human Microbiome.

18 May 2017

publication

Proteome remodelling by the stress sigma factor RpoS/σS in Salmonella: identification of small proteins and evidence for post-transcriptional regulation.

23 Mar 2017

publication

Large-Scale SRM Screen of Urothelial Bladder Cancer Candidate Biomarkers in Urine

27 Jan 2017

event

HDX-MS/NMR DAY

21 Dec 2016

publication

Determination of differentially regulated proteins upon proteasome inhibition in AML cell lines by the combination of large-scale and targeted quantitative proteomics

13 Oct 2016

publication

Liver ubiquitome uncovers nutrient-stress-mediated trafficking and secretion of complement C3

18 Jul 2016

publication

Protection against malaria in mice is induced by blood stage-arresting histamine-releasing factor (HRF)-deficient parasites.

20 Apr 2016

event

Do not forget the next Citech seminar with Dr Ulf Landegren !

10 Mar 2016

publication

The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A

20 Jan 2016

project

SUPERCPLX

07 Sep 2015

project

PTR 539 – A multilevel systems approach to elucidate the host-Leishmania interactome and to identify host targets for anti-leishmanial drug discovery

07 Aug 2015

publication

Prediction of colorectal cancer diagnosis based on circulating plasma proteins

16 Jul 2015

publication

The COPII complex and lysosomal VAMP7 determine intracellular Salmonella localization and growth.

11 May 2015

team

Mass Spectrometry for Biology

17 Feb 2015

team

Proteomics

09 Feb 2015

project

Post translational modifications (PTM)

09 Feb 2015

project

Interaction Proteomics

08 Feb 2015

project

Quantitative Proteomics

18 Jul 2014

publication

Quantitative ADME proteomics – CYP and UGT enzymes in the Beagle dog liver and intestine

04 Mar 2014

publication

A repository of assays to quantify 10,000 human proteins by SWATH-MS.

19 Nov 2013

publication

Statistical approach to protein quantification

15 Jul 2011

publication

Muscle actin is polyubiquitinylated in vitro and in vivo and targeted for breakdown by the E3 ligase MuRF1

16 Feb 2011

publication

Systematic quantification of peptides/proteins in urine using selected reaction monitoring

16 Feb 2011

publication

Toward a standardized urine proteome analysis methodology

06 Oct 2009

publication

Proteasome inhibitor-induced apoptosis in acute myeloid leukemia: a correlation with the proteasome status

03 Feb 2009

publication

Affinity purification strategy to capture human endogenous proteasome complexes diversity and to identify proteasome-interacting proteins

01 Jan 2008

publication

Purification and proteomic analysis of 20S proteasomes from human cells

01 Jun 2005

publication

A quantitative proteomic approach using two-dimensional gel electrophoresis and isotope-coded affinity tag labeling for studying human 20S proteasome heterogeneity

18 May 2005

publication

Long-term morphine treatment enhances proteasome-dependent degradation of G beta in human neuroblastoma SH-SY5Y cells: correlation with onset of adenylate cyclase sensitization

A little guide for advanced search:

NAD kinase promotes Staphylococcus aureus pathogenesis by supporting production of virulence factors and protective enzymes.

RNase E and HupB dynamics foster mycobacterial cell homeostasis and fitness.

TheraEPI

Experimental evolution links post-transcriptional regulation to Leishmania fitness gain.

Phenotypic adaptation to antibiotics: t/rRNA modifications

Listeriolysin S: A bacteriocin from Listeria monocytogenes that induces membrane permeabilization in a contact-dependent manner.

New Highlighted publication: “Cryptococcus extracellular vesicles properties and their use as vaccine platforms”, Juliana Rizzo et al. JEV, 2021, RNA Biology of Fungal Pathogen team

Cryptococcus extracellular vesicles properties and their use as vaccine platforms.

Quality standards in proteomics research facilities: Common standards and quality procedures are essential for proteomics facilities and their users.

Ser/Thr Kinase-Dependent Phosphorylation of the Peptidoglycan Hydrolase CwlA Controls Its Export and Modulates Cell Division in Clostridioides difficile.

RNase R is associated in a functional complex with the RhpA DEAD-box RNA helicase in Helicobacter pylori.

Proteomic Analysis Uncovers Measles Virus Protein C Interaction with p65/iASPP Protein Complex.

Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein.

Insights into amebiasis using a human 3D-intestinal model (ANR-14-IFEC-0001-02)

CYP450 core involvement in multiple resistance strains of Aedes aegypti from French Guiana highlighted by proteomics, molecular and biochemical studies.

Proteomic Analysis of Humoral Immune Components in Bronchoalveolar Lavage of Patients Infected or Colonized by Aspergillus fumigatus.

Mass-spectrometry analysis of the human pineal proteome during night and day and in autism.

ProteoCombiner

EPIC-XS: European Proteomics Infrastructure Consortium providing access

ProteoCombiner: integrating bottom-up with top-down proteomics data for improved proteoform assessment.

Phosphorylation-Dependent Assembly of a 14-3-3 Mediated Signaling Complex during Red Blood Cell Invasion by Plasmodium falciparum Merozoites.

Characterization of Extracellular Vesicles Produced by Aspergillus fumigatus Protoplasts.

Insights into amebiasis using a human 3D-intestinal model.

Shigella hijacks the exocyst to cluster macropinosomes for efficient vacuolar escape.

Differentiation-dependent susceptibility of human muscle cells to Zika virus infection.

Human Immune Response Triggered by Entamoeba histolytica in a 3D-Intestinal Model

The Flemmingsome reveals an ESCRT-to-membrane coupling via ALIX/syntenin/syndecan-4 required for completion of cytokinesis.

The Flemmingsome reveals an ESCRT-to-membrane coupling via ALIX/syntenin/syndecan-4 required for completion of cytokinesis.

Infection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis in epithelial cells.

Impact of the gut microbiota on the m6A epitranscriptome of mouse cecum and liver.

The transpeptidase PBP2 governs initial localization and activity of the major cell-wall synthesis machinery in E. coli.

Listeria monocytogenes Exploits Mitochondrial Contact Site and Cristae Organizing System Complex Subunit Mic10 To Promote Mitochondrial Fragmentation and Cellular Infection.

Class-A penicillin binding proteins do not contribute to cell shape but repair cell-wall defects

Class-A penicillin binding proteins do not contribute to cell shape but repair cell-wall defects.

Comparison of a human neuronal model proteome upon Japanese encephalitis or West Nile Virus infection and potential role of mosquito saliva in neuropathogenesis.

Dynamic Growth and Shrinkage of the Salmonella-Containing Vacuole Determines the Intracellular Pathogen Niche.

Assembly and disassembly of Aspergillus fumigatus conidial rodlets

Assembly and disassembly of Aspergillus fumigatus conidial rodlets.

Single Cell Proteomics

Proteomics Platform satisfaction Survey 2019

Landscape of protein ubiquitylation during infection by CNF1-producing uropathogenic E. coli

Cell-wall synthases contribute to bacterial cell-envelope integrity by actively repairing defects

The Ser/Thr Kinase PrkC Participates in Cell Wall Homeostasis and Antimicrobial Resistance in Clostridium difficile.

RadD Contributes to R-Loop Avoidance in Sub-MIC Tobramycin.

Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype.

Post-translational acylation controls the folding and functions of the CyaA RTX toxin.

The puzzling construction of the conidial outer layer of Aspergillus fumigatus.

Assembly and disassembly of Aspergillus fumigatus conidial rodlets

CotL, a new morphogenetic spore coat protein of Clostridium difficile.

The Adenylate Cyclase (CyaA) Toxin from Bordetella pertussis Has No Detectable Phospholipase A (PLA) Activity In Vitro.

MicroOmiX : Enabling droplet microfluidics technologies

Role of tubulin glutamylation in flagellum construction (TUBGLUFLA)

Infection Reveals a Modification of SIRT2 Critical for Chromatin Association.

MUB40 Binds to Lactoferrin and Stands as a Specific Neutrophil Marker.

Proteomic analysis of plasma extracellular vesicles reveals mitochondrial stress upon HTLV-1 infection.

Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates.

Outer Membrane Proteome of Veillonella parvula: A Diderm Firmicute of the Human Microbiome.

Proteome remodelling by the stress sigma factor RpoS/σS in Salmonella: identification of small proteins and evidence for post-transcriptional regulation.

Large-Scale SRM Screen of Urothelial Bladder Cancer Candidate Biomarkers in Urine

HDX-MS/NMR DAY

Determination of differentially regulated proteins upon proteasome inhibition in AML cell lines by the combination of large-scale and targeted quantitative proteomics

Liver ubiquitome uncovers nutrient-stress-mediated trafficking and secretion of complement C3

Protection against malaria in mice is induced by blood stage-arresting histamine-releasing factor (HRF)-deficient parasites.

Do not forget the next Citech seminar with Dr Ulf Landegren !

The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A

SUPERCPLX

PTR 539 – A multilevel systems approach to elucidate the host-Leishmania interactome and to identify host targets for anti-leishmanial drug discovery

Prediction of colorectal cancer diagnosis based on circulating plasma proteins

The COPII complex and lysosomal VAMP7 determine intracellular Salmonella localization and growth.

Mass Spectrometry for Biology

Proteomics

Post translational modifications (PTM)

Interaction Proteomics

Quantitative Proteomics

Quantitative ADME proteomics – CYP and UGT enzymes in the Beagle dog liver and intestine

A repository of assays to quantify 10,000 human proteins by SWATH-MS.

Statistical approach to protein quantification

Muscle actin is polyubiquitinylated in vitro and in vivo and targeted for breakdown by the E3 ligase MuRF1

Systematic quantification of peptides/proteins in urine using selected reaction monitoring