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  • center
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  • nrc
  • whocc
  • project
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  • tool
  • patent
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  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinical Research Nurse
  • Clinician Researcher
  • Department Manager
  • Dual-education Student
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • Non-permanent Researcher
  • Nursing Staff
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Prize
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  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
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About

Previously controlled bacterial infections can re-emerge due to antibiotic resistance or vaccine escape. Species of pathogenic bacteria comprise a huge amount of genotypic and phenotypic diversity. Our lab is interested in the diversity, evolution and epidemiology of bacterial pathogens and in the links between the genotypic and phenotypic (ecology, colonization, transmission, virulence, antibiotic resistance, immune response) diversity of the strains within particular species. We focus on three pathogens of high public health importance: the multidrug resistant Klebsiella pneumoniae, which causes various types of infections including urinary tract, respiratory and blood infections; Bordetella pertussis, the agent of whooping cough; and Corynebacterium diphtheriae, the agent of diphtheria. We combine epidemiological surveillance, microbiology, genomics, proteomics, bioinformatics and immunological approaches as well as in-vivo and in-vitro models of infection. We also develop and maintain genomic libraries of bacterial genotypes and strain nomenclatures that facilitate global collaborative surveillance and population biology of bacterial pathogens.

Members

Former Members

2000
2000
Name
Position
2017
2019
Marina Barros
Post-doc
2017
2019
Melody Dazas
Technician
2017
2019
Sandra Corre
Research Engineer
2017
2019
Leonardo-Gabriel Panunzi
Post-doc
2017
2019
Juan Sebastián López Fernández
Post-doc
2017
2019
Nadine Pouradier
Technician
2017
2019
Pierre Tonnerre
Post-doc
2017
2019
Pauline Leroux
Graduate Student
2016
2022
Sophie Guillot
Deputy-Head NRC Whooping Cough
2020
2023
Sebastien Bridel
Post-doc
2016
2022
Isabelle Moulherat
Assistant
2020
2023
Soraya Matczack
PhD student
2018
2023
Melanie Hennart
PhD Student and post-doc
2016
2023
Annick Carmi-Leroy
Technician
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Courses

Bacterial strain nomenclatures applied to international epidemiological surveillance: A Theoretical and Hands-on Course

This two-day course will provide participants both theory and hands-on practical exercises on bacterial strain nomenclatures using the core genome MLST concept. Focus will be put on the BIGSdb software tool and database and […]

2018-10-29 10:00:00 2018-10-30 17:00:00 Europe/Paris Bacterial strain nomenclatures applied to international epidemiological surveillance: A Theoretical and Hands-on Course This two-day course will provide participants both theory and hands-on practical exercises on bacterial strain nomenclatures using the core genome MLST concept. Focus will be put on the BIGSdb software tool and database and […] 25 Rue du Dr Roux, 75015 Paris, France

Projects

Transversal Project

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Contact

Phone: +33 1 45 68  80 05 E-mail: isabelle.moulherat@pasteur.fr Address 25-28 Rue du Docteur Roux 75015, Paris France