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  • Deputy Director of National Reference Center
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  • Director of Center
  • Director of Department
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About

Graduated in Pharmaceutical Sciences at Faculdade de Farmácia da Universidade do Porto in 2010, I completed my PhD degree in Pharmacy – Microbiology Specialty in the same institution in July 2017. The work performed during my PhD sought to elucidate the molecular basis for the expansion of main multidrug resistant (MDR) bacterial pathogens (especially Klebsiella pneumoniae) by a multidisciplinary approach including conventional genotypic, phenotypic, and molecular tools and some of the most cutting-edge high-throughput omics (genomics, metabolomics, proteomics) approaches. On the behalf of my PhD, I have been awarded with the Young Investigation Award – Isabel Spencer Martins by Portuguese Society of Microbiology in 2017.  I have joined the BEBP Uunit at Institut Pasteur in 2018, to work as a postdoctoral researcher on the MEDVETKLEBS project.  This project aimed to develop and harmonize detection and strain culture methods for K. pneumoniae, organise broad sampling of ecological niches and of potential sources of this bacterium in order to perform genomics analysis and transmission modeling, including development of new methods for source attribution and risk assessment. In January 2023, I have joined the NRC of whooping cough and other Bordetella infections, hosted in the BEBP unit, as deputy director.

Projects

Project
Ongoing
4 Members

PER-SEVERE: Defining the contribution of variable microbial factors and host immunity to pertussis severity

Carla Rodrigues (PI)

Whooping cough is a respiratory disease caused by a bacterium (Bordetella Pertussis) which can, in certain cases and in particular in infants, be severe or even fatal (this is called malignant whooping cough). The […]
Project
Ongoing
34 Members

Welcome to the Nanopore User Group at Institut Pasteur webpage

Chiara Crestani (PI)

About the Nanopore User Group: The Nanopore User Group at Institut Pasteur was established in 2019 with the primary goal of fostering collaboration, sharing knowledge, and advancing the application of Oxford Nanopore Technologies (ONT) […]
Project
Ongoing
3 Members

KlebNet: a One Health network bridging science and surveillance on antimicrobial resistant Klebsiella

Sylvain Brisse (PI)

Join us on Google groups! KlebNET e-mail distribution list on Google groups. Please ask for registration, by explaining your interest in Klebsiella research or surveillance and providing your institution, so that the moderators can […]
Project
Ongoing
8 Members

Bordetella and whooping cough: Population Biology and Vaccination

Sylvain Brisse (PI)

Our research on Bordetella ranges from the population biology and epidemiology of various Bordetella species, including Bordetella pertussis (the major agent of whooping cough), to studies of host-pathogen relationships and immunity. Current research lines […]
Project
Ongoing
7 Members

Population biology of the bacterial pathogen Klebsiella pneumoniae

Sylvain Brisse (PI)

Klebsiella pneumoniae is one of the most urgent threats to public health given its increasing resistance to antimicrobial agents including carbapenems, considered as last-resort antibiotics.  In this project we aim to understand the ecological, epidemiological and […]
Project
Ongoing
15 Members

Genomic taxonomy of bacterial strains: universal nomenclatures for epidemiology and population biology

Sylvain Brisse (PI)

High-throughput sequencing has revolutionized our abilities to track and characterize novel bacterial strains as they emerge and disseminate globally. Genome-based epidemiological typing systems provide ultimate resolution for strain discrimination. Genome sequences may also be […]

Publications

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