Our research on Corynebacterium diphtheriae and related bacterial pathogenic species, including Corynebacterium ulcerans, aims at defining the diversity, evolution and epidemiology of the agents of diphtheria and related infections. We study human and animal clinical isolates from the collection of prospectively collected isolates from mainland France and overseas territories, and develop international collaborations to define global diversity and geographic spread of sublineages. We combine genomics and phenotyping approaches to define the population dynamics of strains, of the diphtheria toxin, and of antimicrobial resistance genes. We apply our research to the improvements of diagnostics, strain genotyping and epidemiological surveillance.
Our projects on diphtheria leverage and reinforce the resources and expertise of the French National Reference Center for diphtheria (officially: the NRC for Corynebacteria of the diphtheriae complex; web pages in French).
Interested to contribute as postdoc, researcher or clinical scientist? Please see our jobs page, or contact us if you see an opportunity to look for a visitor/fellowship/grant.