Timeline

26 May 2020

publication

Genetic dissection of Rift Valley fever pathogenesis: Rvfs2 locus on mouse chromosome 11 enables survival to early-onset hepatitis.

27 Apr 2018

publication

Identification of new loci involved in the host susceptibility to Salmonella Typhimurium in collaborative cross mice

01 Feb 2016

publication

Haplosufficiency of PAX3 for melanoma development in Tyr: NRASQ61K; Cdkn2a-/- mice allows identification and sorting of melanoma cells using a Pax3GFP reporter allele

06 Jan 2016

news

SEMINAR “The imprinted H19 non coding RNA in the embryo and in adult muscle stem cells”

12 Oct 2015

publication

β-Catenin Upregulates the Constitutive and Virus-Induced Transcriptional Capacity of the Interferon Beta Promoter through T-Cell Factor Binding Sites

17 Sep 2015

news

Club des Belles Souris

08 Sep 2015

project

Pathogenicity and resistance to Rift Valley Fever virus.

09 Jun 2015

project

Biology of embryonic and adult stem cells

08 Jan 2015

publication

The genetic basis for susceptibility to Rift Valley fever disease in MBT/Pas mice

01 Jan 2015

publication

Genetics of the mouse

01 Oct 2014

publication

The Rift Valley fever accessory proteins NSm and P78/NSm-GN are distinct determinants of virus propagation in vertebrate and invertebrate hosts

04 Jun 2013

publication

Canine melanoma diagnosis: RACK1 as a potential biological marker

01 May 2013

publication

Controlling complexity: the clinical relevance of mouse complex genetics

15 Nov 2012

publication

Resistance to plague of Mus spretus SEG/Pas mice requires the combined action of at least four genetic factors

23 Oct 2012

publication

IS-98-ST1 West Nile virus derived from an infectious cDNA clone retains neuroinvasiveness and neurovirulence properties of the original virus

05 Oct 2012

publication

Centronuclear myopathy in Labrador retrievers: a recent founder mutation in the PTPLA gene has rapidly disseminated worldwide

12 Jul 2012

publication

Pax3( GFP ) , a new reporter for the melanocyte lineage, highlights novel aspects of PAX3 expression in the skin

29 Jun 2012

publication

RACK1, a clue to the diagnosis of cutaneous melanomas in horses

04 May 2012

publication

p53 Activation following Rift Valley fever virus infection contributes to cell death and viral production

18 Apr 2012

publication

MBT/Pas mouse: a relevant model for the evaluation of Rift Valley fever vaccines

27 Jan 2012

publication

[The Collaborative Cross, a groundbreaking tool to tackle complex traits]

06 Dec 2011

publication

Tissue tropism and target cells of NSs-deleted rift valley fever virus in live immunodeficient mice

16 Nov 2011

publication

Early systemic bacterial dissemination and a rapid innate immune response characterize genetic resistance to plague of SEG mice

17 Jun 2011

publication

Transgenic expression of full-length 2′,5′-oligoadenylate synthetase 1b confers to BALB/c mice resistance against West Nile virus-induced encephalitis

28 Jan 2011

publication

Evolution of major milk proteins in Mus musculus and Mus spretus mouse species: a genoproteomic analysis

11 Oct 2010

publication

A new mouse model reveals a critical role for host innate immunity in resistance to Rift Valley fever

23 Sep 2010

publication

Mus spretus SEG/Pas mice resist virulent Yersinia pestis, under multigenic control

08 Sep 2010

publication

A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst

02 Aug 2010

publication

A canine Arylsulfatase G (ARSG) mutation leading to a sulfatase deficiency is associated with neuronal ceroid lipofuscinosis

28 Jan 2010

publication

Gene expression changes in the host response between resistant and susceptible inbred mouse strains after influenza A infection

01 Oct 2009

publication

The major protein fraction of mouse milk revisited using proven proteomic tools

14 May 2008

publication

Uterine contractions depend on KIT-positive interstitial cells in the mouse: genetic and pharmacological evidence

08 May 2008

publication

Melanoblasts’ proper location and timed differentiation depend on Notch/RBP-J signaling in postnatal hair follicles

08 May 2008

publication

[Melanocyte stem cells in adults]

28 Apr 2008

publication

Transcription analysis in the MeLiM swine model identifies RACK1 as a potential marker of malignancy for human melanocytic proliferation

18 Oct 2007

publication

Interspecific recombinant congenic strains between C57BL/6 and mice of the Mus spretus species: a powerful tool to dissect genetic control of complex traits

05 Jul 2007

publication

KIT is required for hepatic function during mouse post-natal development

04 Jul 2006

publication

The survival of differentiating embryonic stem cells is dependent on the SCF-KIT pathway

01 Jun 2005

publication

Cooperative and indispensable roles of endothelin 3 and KIT signalings in melanocyte development

13 Apr 2005

publication

SINE exonic insertion in the PTPLA gene leads to multiple splicing defects and segregates with the autosomal recessive centronuclear myopathy in dogs

17 Nov 2004

publication

Neural crest cell lineage segregation in the mouse neural tube

05 Aug 2004

publication

Accelerated intestinal transit in inbred mice with an increased number of interstitial cells of Cajal

01 Apr 2004

publication

Premature stop codons involved in muscular dystrophies show a broad spectrum of readthrough efficiencies in response to gentamicin treatment

16 Dec 2003

publication

Genetic interaction between a maternal factor and the zygotic genome controls the intestine length in PRM/Alf mice

01 Aug 2003

publication

Establishment and characterization of a normal melanocyte cell line derived from pig skin

23 Jul 2003

publication

The cnm locus, a canine homologue of human autosomal forms of centronuclear myopathy, maps to chromosome 2

21 Jan 2003

publication

The mouse organellar biogenesis mutant buff results from a mutation in Vps33a, a homologue of yeast vps33 and Drosophila carnation

01 Jan 2003

publication

Les organismes modèles – Génétique de la Souris

23 Oct 2002

publication

Kit-negative fibroblast-like cells expressing SK3, a Ca2+-activated K+ channel, in the gut musculature in health and disease

01 Jul 2002

publication

Apoptosis, onset and maintenance of spermatogenesis: evidence for the involvement of Kit in Kit-haplodeficient mice

01 Oct 2001

publication

Interstitial cells of Cajal in the striated musculature of the mouse esophagus

01 Sep 2001

publication

Expression of the receptor tyrosine kinase KIT in mature beta-cells and in the pancreas in development

01 Feb 2001

publication

Alterations in ovarian function of mice with reduced amounts of KIT receptor

01 Dec 2000

publication

Signaling and transcriptional regulation in the neural crest-derived melanocyte lineage: interactions between KIT and MITF

01 Nov 2000

publication

Distribution and ultrastructure of interstitial cells of Cajal in the mouse colon, using antibodies to Kit and Kit(W-lacZ) mice

01 Nov 2000

publication

Twister mutant mice are defective for otogelin, a component specific to inner ear acellular membranes

01 Aug 2000

publication

Assignation of highly polymorphic markers on a canine purebred pedigree

01 Feb 2000

publication

Targeted disruption of otog results in deafness and severe imbalance

01 Dec 1999

publication

Characterization and mapping of canine polymorphic markers

01 Dec 1999

publication

Identification and characterization of a melanocyte-specific novel 65-kDa peripheral membrane protein

01 Dec 1999

publication

A novel model to study the dorsolateral migration of melanoblasts

01 Jul 1999

publication

Analysis of major repetitive DNA sequences in the dog (Canis familiaris) genome

01 Jun 1999

publication

The patchwork mouse phenotype: implication for melanocyte replacement in the hair follicle

15 Jun 1998

publication

Survival of patchwork melanoblasts is dependent upon their number in the hair follicle at the end of embryogenesis

01 Jun 1997

publication

Multiple neuroendocrine tumours in transgenic mice induced by c-kit-SV40 T antigen fusion genes

01 Dec 1996

publication

Polymorphism characterization of five canine microsatellites

01 Oct 1996

publication

Spatial and temporal patterns of c-kit-expressing cells in WlacZ/+ and WlacZ/WlacZ mouse embryos

01 Nov 1995

publication

Phenotypic reversions at the W/Kit locus mediated by mitotic recombination in mice

26 Jun 1995

publication

SARs do not impair position-dependent expression of a kit/lacZ transgene

01 Oct 1994

publication

The spread of a replication-competent MuLV retroviral vector can be efficiently blocked by deletion variants

01 Sep 1994

publication

Immortalization of multiple cell types from transgenic mice using a transgene containing the vimentin promoter and a conditional oncogene

01 Sep 1994

publication

Instability at the W/c-kit locus in mice: analysis of melanocyte cell lines derived from reversion spots

01 Mar 1993

publication

Analysis of variability among endogenous ecotropic MuLV loci in laboratory mice

01 Jul 1991

publication

Mitotic recombination in mammals

01 May 1990

publication

Evidence for mitotic recombination in Wei/+ heterozygous mice

01 Oct 1989

publication

Acquisition of endogenous ecotropic MuLV can occur before the late one-cell stage in the genital tract of SWR/J-RF/J hybrid females

01 May 1989

publication

Pattern of expression of ecotropic murine leukemia virus in gonads of inoculated SWR/J mice

01 Feb 1988

publication

Inoculation of newborn SWR/J females with an ecotropic murine leukemia virus can produce transgenic mice

01 Jan 1986

publication

Segmental homology between the promoter region of the human renin gene and the mouse ren1 and ren2 promoter regions

01 Nov 1985

publication

Nonproportional changes in plasma renin concentration, renal renin content, and rat renin messenger RNA

01 Sep 1984

publication

Mouse kidney and submaxillary gland renin genes differ in their 5′ putative regulatory sequences

01 Mar 1984

publication

Evolution of aspartyl proteases by gene duplication: the mouse renin gene is organized in two homologous clusters of four exons

25 Oct 1983

publication

Molecular cloning and nucleotide sequence of a human renin cDNA fragment

01 Oct 1983

publication

Mouse submaxillary renin: a useful model for the study of renal renin

01 Mar 1983

publication

Structure of the mouse submaxillary gland renin precursor and a model for renin processing. Arthur C. Corcoran Memorial Lecture

01 Jan 1983

publication

Kidney and submaxillary gland renins are encoded by two non-allelic genes in Swiss mice

01 Jul 1982

publication

Complete amino acid sequence and maturation of the mouse submaxillary gland renin precursor

01 Jan 1982

publication

The mouse Rn locus: S allele of the renin regulator gene results from a single structural gene duplication

01 Oct 1981

publication

Molecular cloning of a mouse submaxillary gland renin cDNA fragment

01 Oct 1980

publication

Cloned ß-galactosidase gene of Escherichia coli is expressed in the yeast Saccharomyces cerevisiae

08 Sep 1979

publication

A little guide for advanced search:

Genetic dissection of Rift Valley fever pathogenesis: Rvfs2 locus on mouse chromosome 11 enables survival to early-onset hepatitis.

Identification of new loci involved in the host susceptibility to Salmonella Typhimurium in collaborative cross mice

Haplosufficiency of PAX3 for melanoma development in Tyr: NRASQ61K; Cdkn2a-/- mice allows identification and sorting of melanoma cells using a Pax3GFP reporter allele

SEMINAR “The imprinted H19 non coding RNA in the embryo and in adult muscle stem cells”

β-Catenin Upregulates the Constitutive and Virus-Induced Transcriptional Capacity of the Interferon Beta Promoter through T-Cell Factor Binding Sites

Club des Belles Souris

Pathogenicity and resistance to Rift Valley Fever virus.

Biology of embryonic and adult stem cells

The genetic basis for susceptibility to Rift Valley fever disease in MBT/Pas mice

Genetics of the mouse

The Rift Valley fever accessory proteins NSm and P78/NSm-GN are distinct determinants of virus propagation in vertebrate and invertebrate hosts

Canine melanoma diagnosis: RACK1 as a potential biological marker

Controlling complexity: the clinical relevance of mouse complex genetics

Resistance to plague of Mus spretus SEG/Pas mice requires the combined action of at least four genetic factors

IS-98-ST1 West Nile virus derived from an infectious cDNA clone retains neuroinvasiveness and neurovirulence properties of the original virus

Centronuclear myopathy in Labrador retrievers: a recent founder mutation in the PTPLA gene has rapidly disseminated worldwide

Pax3( GFP ) , a new reporter for the melanocyte lineage, highlights novel aspects of PAX3 expression in the skin

RACK1, a clue to the diagnosis of cutaneous melanomas in horses

p53 Activation following Rift Valley fever virus infection contributes to cell death and viral production

MBT/Pas mouse: a relevant model for the evaluation of Rift Valley fever vaccines

[The Collaborative Cross, a groundbreaking tool to tackle complex traits]

Tissue tropism and target cells of NSs-deleted rift valley fever virus in live immunodeficient mice

Early systemic bacterial dissemination and a rapid innate immune response characterize genetic resistance to plague of SEG mice

Transgenic expression of full-length 2′,5′-oligoadenylate synthetase 1b confers to BALB/c mice resistance against West Nile virus-induced encephalitis

Evolution of major milk proteins in Mus musculus and Mus spretus mouse species: a genoproteomic analysis

A new mouse model reveals a critical role for host innate immunity in resistance to Rift Valley fever

Mus spretus SEG/Pas mice resist virulent Yersinia pestis, under multigenic control

A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst

A canine Arylsulfatase G (ARSG) mutation leading to a sulfatase deficiency is associated with neuronal ceroid lipofuscinosis

Gene expression changes in the host response between resistant and susceptible inbred mouse strains after influenza A infection

The major protein fraction of mouse milk revisited using proven proteomic tools

Uterine contractions depend on KIT-positive interstitial cells in the mouse: genetic and pharmacological evidence

Melanoblasts’ proper location and timed differentiation depend on Notch/RBP-J signaling in postnatal hair follicles

[Melanocyte stem cells in adults]

Transcription analysis in the MeLiM swine model identifies RACK1 as a potential marker of malignancy for human melanocytic proliferation

Interspecific recombinant congenic strains between C57BL/6 and mice of the Mus spretus species: a powerful tool to dissect genetic control of complex traits

KIT is required for hepatic function during mouse post-natal development

The survival of differentiating embryonic stem cells is dependent on the SCF-KIT pathway

Cooperative and indispensable roles of endothelin 3 and KIT signalings in melanocyte development

SINE exonic insertion in the PTPLA gene leads to multiple splicing defects and segregates with the autosomal recessive centronuclear myopathy in dogs

Neural crest cell lineage segregation in the mouse neural tube

Accelerated intestinal transit in inbred mice with an increased number of interstitial cells of Cajal

Premature stop codons involved in muscular dystrophies show a broad spectrum of readthrough efficiencies in response to gentamicin treatment

Genetic interaction between a maternal factor and the zygotic genome controls the intestine length in PRM/Alf mice

Establishment and characterization of a normal melanocyte cell line derived from pig skin

The cnm locus, a canine homologue of human autosomal forms of centronuclear myopathy, maps to chromosome 2

The mouse organellar biogenesis mutant buff results from a mutation in Vps33a, a homologue of yeast vps33 and Drosophila carnation

Les organismes modèles – Génétique de la Souris

Kit-negative fibroblast-like cells expressing SK3, a Ca2+-activated K+ channel, in the gut musculature in health and disease

Apoptosis, onset and maintenance of spermatogenesis: evidence for the involvement of Kit in Kit-haplodeficient mice

Interstitial cells of Cajal in the striated musculature of the mouse esophagus

Expression of the receptor tyrosine kinase KIT in mature beta-cells and in the pancreas in development

Alterations in ovarian function of mice with reduced amounts of KIT receptor

Signaling and transcriptional regulation in the neural crest-derived melanocyte lineage: interactions between KIT and MITF

Distribution and ultrastructure of interstitial cells of Cajal in the mouse colon, using antibodies to Kit and Kit(W-lacZ) mice

Twister mutant mice are defective for otogelin, a component specific to inner ear acellular membranes

Assignation of highly polymorphic markers on a canine purebred pedigree

Targeted disruption of otog results in deafness and severe imbalance

Characterization and mapping of canine polymorphic markers

Identification and characterization of a melanocyte-specific novel 65-kDa peripheral membrane protein

A novel model to study the dorsolateral migration of melanoblasts

Analysis of major repetitive DNA sequences in the dog (Canis familiaris) genome

The patchwork mouse phenotype: implication for melanocyte replacement in the hair follicle

Survival of patchwork melanoblasts is dependent upon their number in the hair follicle at the end of embryogenesis

Multiple neuroendocrine tumours in transgenic mice induced by c-kit-SV40 T antigen fusion genes

Polymorphism characterization of five canine microsatellites

Spatial and temporal patterns of c-kit-expressing cells in WlacZ/+ and WlacZ/WlacZ mouse embryos

Phenotypic reversions at the W/Kit locus mediated by mitotic recombination in mice

SARs do not impair position-dependent expression of a kit/lacZ transgene

The spread of a replication-competent MuLV retroviral vector can be efficiently blocked by deletion variants

Immortalization of multiple cell types from transgenic mice using a transgene containing the vimentin promoter and a conditional oncogene

Instability at the W/c-kit locus in mice: analysis of melanocyte cell lines derived from reversion spots

Analysis of variability among endogenous ecotropic MuLV loci in laboratory mice

Mitotic recombination in mammals

Evidence for mitotic recombination in Wei/+ heterozygous mice

Acquisition of endogenous ecotropic MuLV can occur before the late one-cell stage in the genital tract of SWR/J-RF/J hybrid females

Pattern of expression of ecotropic murine leukemia virus in gonads of inoculated SWR/J mice

Inoculation of newborn SWR/J females with an ecotropic murine leukemia virus can produce transgenic mice

Segmental homology between the promoter region of the human renin gene and the mouse ren1 and ren2 promoter regions