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© Research
Publication : Molecular cancer

Transcription analysis in the MeLiM swine model identifies RACK1 as a potential marker of malignancy for human melanocytic proliferation

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Molecular cancer - 28 Apr 2008

Egidy G, Julé S, Bossé P, Bernex F, Geffrotin C, Vincent-Naulleau S, Horak V, Sastre-Garau X, Panthier JJ

Link to Pubmed [PMID] – 18442364

Mol. Cancer 2008;7:34

Metastatic melanoma is a severe disease. Few experimental animal models of metastatic melanoma exist. MeLiM minipigs exhibit spontaneous melanoma. Cutaneous and metastatic lesions are histologically similar to human’s. However, most of them eventually spontaneously regress. Our purpose was to investigate whether the MeLiM model could reveal markers of malignancy in human melanocytic proliferations.

http://www.ncbi.nlm.nih.gov/pubmed/18442364