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© Xavier Montagutelli, Institut Pasteur
Publication : European journal of human genetics : EJHG

Controlling complexity: the clinical relevance of mouse complex genetics

Team: Mouse Genetics
Member: Xavier Montagutelli
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in European journal of human genetics : EJHG - 01 May 2013

Schughart K, Libert C, , Kas MJ

Link to Pubmed [PMID] – 23632795

Eur. J. Hum. Genet. 2013 Nov;21(11):1191-6

Experimental animal models are essential to obtain basic knowledge of the underlying biological mechanisms in human diseases. Here, we review major contributions to biomedical research and discoveries that were obtained in the mouse model by using forward genetics approaches and that provided key insights into the biology of human diseases and paved the way for the development of novel therapeutic approaches.