Timeline

Isabelle Martin-Verstraete

Group Leader

08 Feb 2024

publication

The multiplicity of thioredoxin systems meets the specific lifestyles of Clostridia.

14 Oct 2022

publication

In-depth characterization of the Clostridioides difficile phosphoproteome to identify Ser/Thr kinase substrates

14 Oct 2022

publication

In-depth characterization of the Clostridioides difficile phosphoproteome to identify Ser/Thr kinase substrates.

15 Feb 2022

publication

Bacteroides thetaiotaomicron uses a widespread extracellular DNase to promote bile-dependent biofilm formation.

05 Oct 2021

publication

Listeriolysin S: A bacteriocin from Listeria monocytogenes that induces membrane permeabilization in a contact-dependent manner.

21 Jun 2021

publication

Metabolic adaption to extracellular pyruvate triggers biofilm formation in Clostridioides difficile.

18 May 2021

publication

Ser/Thr Kinase-Dependent Phosphorylation of the Peptidoglycan Hydrolase CwlA Controls Its Export and Modulates Cell Division in Clostridioides difficile.

08 Sep 2020

publication

How the Anaerobic Enteropathogen Clostridioides difficile Tolerates Low O2 Tensions.

20 Aug 2018

publication

Clostridium difficile biofilm: remodeling metabolism and cell surface to build a sparse and heterogeneously aggregated architecture

24 Apr 2017

publication

Silver potentiates aminoglycoside toxicity by enhancing their uptake

22 Sep 2016

course

Workshop: Bacterial RNAseq

14 Oct 2015

project

Biology of anaerobic biofilm formed by Clostridium difficile and their role in infections

13 Oct 2015

project

The regulatory network of sporulation and spore morphogenesis in Clostridium difficile

16 Jul 2015

team

Group: Isabelle Martin-Verstraete

11 May 2015

team

Pathogenesis of Bacterial Anaerobes

12 Aug 2014

publication

The regulatory network controlling spore formation in Clostridium difficile

30 Jun 2014

publication

Pleiotropic role of the RNA chaperone protein Hfq in the human pathogen Clostridium difficile

01 Jan 2014

publication

Riboswitch discovery by combining RNA-seq and genome-wide identification of transcriptional start sites

03 Oct 2013

publication

Genome-wide analysis of cell type-specific gene transcription during spore formation in Clostridium difficile

16 Sep 2013

project

Control of toxin synthesis and secretion in Clostridium difficile

09 May 2013

publication

Genome-wide identification of regulatory RNAs in the human pathogen Clostridium difficile

11 Dec 2012

publication

PlcRa, a new quorum-sensing regulator from Bacillus cereus, plays a role in oxidative stress responses and cysteine metabolism in stationary phase

18 Sep 2012

publication

Global transcriptional control by glucose and carbon regulator CcpA in Clostridium difficile

01 Jul 2011

publication

Insights into the Rrf2 repressor family–the structure of CymR, the global cysteine regulator of Bacillus subtilis

13 May 2011

publication

The key sigma factor of transition phase, SigH, controls sporulation, metabolism, and virulence factor expression in Clostridium difficile

17 Dec 2010

publication

Global regulation of the response to sulfur availability in the cheese-related bacterium Brevibacterium aurantiacum

07 Sep 2010

publication

Global regulation of gene expression in response to cysteine availability in Clostridium perfringens

17 Jun 2010

publication

Complex phenotypes of a mutant inactivated for CymR, the global regulator of cysteine metabolism in Bacillus subtilis

13 May 2010

publication

The pleiotropic CymR regulator of Staphylococcus aureus plays an important role in virulence and stress response

31 Jul 2009

publication

Identification of brevibacteriaceae by multilocus sequence typing and comparative genomic hybridization analyses

08 Jun 2009

publication

CymR, the master regulator of cysteine metabolism in Staphylococcus aureus, controls host sulphur source utilization and plays a role in biofilm formation

23 Sep 2008

publication

S-box and T-box riboswitches and antisense RNA control a sulfur metabolic operon of Clostridium acetobutylicum

28 Jul 2008

publication

Spx mediates oxidative stress regulation of the methionine sulfoxide reductases operon in Bacillus subtilis

26 Feb 2008

publication

Reconstruction and analysis of the genetic and metabolic regulatory networks of the central metabolism of Bacillus subtilis

03 Aug 2007

publication

Control of methionine synthesis and uptake by MetR and homocysteine in Streptococcus mutans

20 Oct 2006

publication

Conversion of methionine to cysteine in Bacillus subtilis and its regulation

01 Mar 2006

publication

Global control of cysteine metabolism by CymR in Bacillus subtilis

01 Sep 2005

publication

Regulation of the Bacillus subtilis ytmI operon, involved in sulfur metabolism

01 Feb 2005

publication

The PatB protein of Bacillus subtilis is a C-S-lyase

01 Aug 2004

publication

Three different systems participate in L-cystine uptake in Bacillus subtilis

01 Mar 2004

publication

The metNPQ operon of Bacillus subtilis encodes an ABC permease transporting methionine sulfoxide, D- and L-methionine

01 Sep 2002

publication

Global expression profile of Bacillus subtilis grown in the presence of sulfate or methionine

01 Sep 2002

publication

Identification of Bacillus subtilis CysL, a regulator of the cysJI operon, which encodes sulfite reductase

01 Feb 2002

publication

The metIC operon involved in methionine biosynthesis in Bacillus subtilis is controlled by transcription antitermination

01 Sep 2001

publication

CotA of Bacillus subtilis is a copper-dependent laccase

01 Aug 2001

publication

Mutations lowering the phosphatase activity of HPr kinase/phosphatase switch off carbon metabolism

01 Jun 2001

publication

Sulfur-limitation-regulated proteins in Bacillus subtilis: a two-dimensional gel electrophoresis study

01 Jun 2001

publication

Characterization of glucose-repression-resistant mutants of Bacillus subtilis: identification of the glcR gene

01 Jun 2000

publication

S-adenosylmethionine decarboxylase of Bacillus subtilis is closely related to archaebacterial counterparts

01 Nov 1999

publication

Catabolite regulation of the pta gene as part of carbon flow pathways in Bacillus subtilis

01 Nov 1999

publication

The Q15H mutation enables Crh, a Bacillus subtilis HPr-like protein, to carry out some regulatory HPr functions, but does not make it an effective phosphocarrier for sugar transport

01 Aug 1999

publication

The catabolite control protein CcpA controls ammonium assimilation in Bacillus subtilis

01 May 1999

publication

Phosphorylation of HPr and Crh by HprK, early steps in the catabolite repression signalling pathway for the Bacillus subtilis levanase operon

19 Feb 1999

publication

Phosphorylation of either crh or HPr mediates binding of CcpA to the bacillus subtilis xyn cre and catabolite repression of the xyn operon

01 Jun 1998

publication

PRD–a protein domain involved in PTS-dependent induction and carbon catabolite repression of catabolic operons in bacteria

01 Apr 1998

publication

Antagonistic effects of dual PTS-catalysed phosphorylation on the Bacillus subtilis transcriptional activator LevR

01 Aug 1997

publication

The Bacillus subtilis crh gene encodes a HPr-like protein involved in carbon catabolite repression

01 Jul 1997

publication

Induction of the Bacillus subtilis ptsGHI operon by glucose is controlled by a novel antiterminator, GlcT

01 Feb 1997

publication

Protein phosphorylation chain of a Bacillus subtilis fructose-specific phosphotransferase system and its participation in regulation of the expression of the lev operon

01 Dec 1996

publication

The levanase operon of Bacillus subtilis expressed in Escherichia coli can substitute for the mannose permease in mannose uptake and bacteriophage lambda infection

01 Dec 1995

publication

Two different mechanisms mediate catabolite repression of the Bacillus subtilis levanase operon

01 Dec 1995

publication

The HPr protein of the phosphotransferase system links induction and catabolite repression of the Bacillus subtilis levanase operon

12 Aug 1994

publication

Interactions of wild-type and truncated LevR of Bacillus subtilis with the upstream activating sequence of the levanase operon

01 Jul 1992

publication

Mutagenesis of the Bacillus subtilis “-12, -24” promoter of the levanase operon and evidence for the existence of an upstream activating sequence

15 Oct 1991

publication

The Bacillus subtilis sigL gene encodes an equivalent of sigma 54 from gram-negative bacteria

01 Sep 1991

publication

Positive and negative regulation controlling expression of the sac genes in Bacillus subtilis

15 Mar 1991

publication

The transcriptional regulator LevR of Bacillus subtilis has domains homologous to both sigma 54- and phosphotransferase system-dependent regulators

01 Aug 1990

publication

Levanase operon of Bacillus subtilis includes a fructose-specific phosphotransferase system regulating the expression of the operon

01 Jun 1987

publication

A little guide for advanced search:

The multiplicity of thioredoxin systems meets the specific lifestyles of Clostridia.

In-depth characterization of the Clostridioides difficile phosphoproteome to identify Ser/Thr kinase substrates

In-depth characterization of the Clostridioides difficile phosphoproteome to identify Ser/Thr kinase substrates.

Bacteroides thetaiotaomicron uses a widespread extracellular DNase to promote bile-dependent biofilm formation.

Listeriolysin S: A bacteriocin from Listeria monocytogenes that induces membrane permeabilization in a contact-dependent manner.

Metabolic adaption to extracellular pyruvate triggers biofilm formation in Clostridioides difficile.

Ser/Thr Kinase-Dependent Phosphorylation of the Peptidoglycan Hydrolase CwlA Controls Its Export and Modulates Cell Division in Clostridioides difficile.

How the Anaerobic Enteropathogen Clostridioides difficile Tolerates Low O2 Tensions.

Clostridium difficile biofilm: remodeling metabolism and cell surface to build a sparse and heterogeneously aggregated architecture

Silver potentiates aminoglycoside toxicity by enhancing their uptake

Workshop: Bacterial RNAseq

Biology of anaerobic biofilm formed by Clostridium difficile and their role in infections

The regulatory network of sporulation and spore morphogenesis in Clostridium difficile

Group: Isabelle Martin-Verstraete

Pathogenesis of Bacterial Anaerobes

The regulatory network controlling spore formation in Clostridium difficile

Pleiotropic role of the RNA chaperone protein Hfq in the human pathogen Clostridium difficile

Riboswitch discovery by combining RNA-seq and genome-wide identification of transcriptional start sites

Genome-wide analysis of cell type-specific gene transcription during spore formation in Clostridium difficile

Control of toxin synthesis and secretion in Clostridium difficile

Genome-wide identification of regulatory RNAs in the human pathogen Clostridium difficile

PlcRa, a new quorum-sensing regulator from Bacillus cereus, plays a role in oxidative stress responses and cysteine metabolism in stationary phase

Global transcriptional control by glucose and carbon regulator CcpA in Clostridium difficile

Insights into the Rrf2 repressor family–the structure of CymR, the global cysteine regulator of Bacillus subtilis

The key sigma factor of transition phase, SigH, controls sporulation, metabolism, and virulence factor expression in Clostridium difficile

Global regulation of the response to sulfur availability in the cheese-related bacterium Brevibacterium aurantiacum

Global regulation of gene expression in response to cysteine availability in Clostridium perfringens

Complex phenotypes of a mutant inactivated for CymR, the global regulator of cysteine metabolism in Bacillus subtilis

The pleiotropic CymR regulator of Staphylococcus aureus plays an important role in virulence and stress response

Identification of brevibacteriaceae by multilocus sequence typing and comparative genomic hybridization analyses

CymR, the master regulator of cysteine metabolism in Staphylococcus aureus, controls host sulphur source utilization and plays a role in biofilm formation

S-box and T-box riboswitches and antisense RNA control a sulfur metabolic operon of Clostridium acetobutylicum

Spx mediates oxidative stress regulation of the methionine sulfoxide reductases operon in Bacillus subtilis

Reconstruction and analysis of the genetic and metabolic regulatory networks of the central metabolism of Bacillus subtilis

Control of methionine synthesis and uptake by MetR and homocysteine in Streptococcus mutans

Conversion of methionine to cysteine in Bacillus subtilis and its regulation

Global control of cysteine metabolism by CymR in Bacillus subtilis

Regulation of the Bacillus subtilis ytmI operon, involved in sulfur metabolism

The PatB protein of Bacillus subtilis is a C-S-lyase

Three different systems participate in L-cystine uptake in Bacillus subtilis

The metNPQ operon of Bacillus subtilis encodes an ABC permease transporting methionine sulfoxide, D- and L-methionine

Global expression profile of Bacillus subtilis grown in the presence of sulfate or methionine

Identification of Bacillus subtilis CysL, a regulator of the cysJI operon, which encodes sulfite reductase

The metIC operon involved in methionine biosynthesis in Bacillus subtilis is controlled by transcription antitermination

CotA of Bacillus subtilis is a copper-dependent laccase

Mutations lowering the phosphatase activity of HPr kinase/phosphatase switch off carbon metabolism

Sulfur-limitation-regulated proteins in Bacillus subtilis: a two-dimensional gel electrophoresis study

Characterization of glucose-repression-resistant mutants of Bacillus subtilis: identification of the glcR gene

S-adenosylmethionine decarboxylase of Bacillus subtilis is closely related to archaebacterial counterparts

Catabolite regulation of the pta gene as part of carbon flow pathways in Bacillus subtilis

The Q15H mutation enables Crh, a Bacillus subtilis HPr-like protein, to carry out some regulatory HPr functions, but does not make it an effective phosphocarrier for sugar transport

The catabolite control protein CcpA controls ammonium assimilation in Bacillus subtilis

Phosphorylation of HPr and Crh by HprK, early steps in the catabolite repression signalling pathway for the Bacillus subtilis levanase operon

Phosphorylation of either crh or HPr mediates binding of CcpA to the bacillus subtilis xyn cre and catabolite repression of the xyn operon

PRD–a protein domain involved in PTS-dependent induction and carbon catabolite repression of catabolic operons in bacteria

Antagonistic effects of dual PTS-catalysed phosphorylation on the Bacillus subtilis transcriptional activator LevR

The Bacillus subtilis crh gene encodes a HPr-like protein involved in carbon catabolite repression

Induction of the Bacillus subtilis ptsGHI operon by glucose is controlled by a novel antiterminator, GlcT

Protein phosphorylation chain of a Bacillus subtilis fructose-specific phosphotransferase system and its participation in regulation of the expression of the lev operon

The levanase operon of Bacillus subtilis expressed in Escherichia coli can substitute for the mannose permease in mannose uptake and bacteriophage lambda infection

Two different mechanisms mediate catabolite repression of the Bacillus subtilis levanase operon

The HPr protein of the phosphotransferase system links induction and catabolite repression of the Bacillus subtilis levanase operon

Interactions of wild-type and truncated LevR of Bacillus subtilis with the upstream activating sequence of the levanase operon

Mutagenesis of the Bacillus subtilis “-12, -24” promoter of the levanase operon and evidence for the existence of an upstream activating sequence

The Bacillus subtilis sigL gene encodes an equivalent of sigma 54 from gram-negative bacteria

Positive and negative regulation controlling expression of the sac genes in Bacillus subtilis

The transcriptional regulator LevR of Bacillus subtilis has domains homologous to both sigma 54- and phosphotransferase system-dependent regulators

Levanase operon of Bacillus subtilis includes a fructose-specific phosphotransferase system regulating the expression of the operon

Characterization of the levanase gene of Bacillus subtilis which shows homology to yeast invertase