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Members
Groups
Laboratory

Biochemistry of Macromolecular Interactions

Daniel Ladant
Laboratory

Structural Microbiology

Pedro Alzari
Laboratory

Architecture and Dynamics of Biological Macromolecules

Marc Delarue
Laboratory

Structural Bioinformatics

Michael Nilges
Laboratory

Bacterial transmembrane systems

Nadia Izadi-Pruneyre
Laboratory

Bacterial Cell Cycle Mechanisms

Anne Marie Wehenkel
Laboratory

Computational Structural Biology

Max Bonomi
Laboratory

Integrative Structural Cell Biology

Ariane Briegel
Publications
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2025Structural Basis for DNA Replication and Uracil Repair in Phage A-Family DNA Polymerases, Biorxiv.
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2025Blunted CD40-responsive enhancer activation in CREBBP-mutant lymphomas can be restored by enforced CD4 T-cell engagement., Blood 2025 Mar; (): .
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2025Vestibular modulation by stimulant derivatives in a pentameric ligand-gated ion channel., Br J Pharmacol 2025 March.
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2025Crystal structures of monomeric BsmI restriction endonuclease reveal coordinated sequential cleavage of two DNA strands., Commun Biol 2025 Mar; 8(1): 387.
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2025Structure and dynamics of a multidomain ligand-gated ion channelrevealed under acidic conditions, Biorxiv 2025.
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2025Evolutionary plasticity and functional repurposing of the essential metabolic enzyme MoeA., Commun Biol 2025 Jan; 8(1): 49.
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2024Communication between DNA polymerases and Replication Protein A within the archaeal replisome., Nat Commun 2024 Dec; 15(1): 10926.
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2024Discovering cryptic pocket opening and binding of a stimulant derivative in a vestibular site of the 5-HT3A receptor, 2024.
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2024Dynamic interplay between a TonB-dependent heme transporter and a TonB protein in a membrane environment, mBio, In press, pp.e0178124. ⟨10.1128/mbio.01781-24⟩.
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2024Molecular mechanism of a triazole-containing inhibitor of Mycobacterium tuberculosis DNA gyrase., iScience 2024 Oct; 27(10): 110967.
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