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Members
Groups
Laboratory

Biochemistry of Macromolecular Interactions

Daniel Ladant
Laboratory

Structural Microbiology

Pedro Alzari
Laboratory

Architecture and Dynamics of Biological Macromolecules

Marc Delarue
Laboratory

Structural Bioinformatics

Michael Nilges
Laboratory

Bacterial transmembrane systems

Nadia Izadi-Pruneyre
Laboratory

Bacterial Cell Cycle Mechanisms

Anne Marie Wehenkel
Laboratory

Computational Structural Biology

Max Bonomi
Laboratory

Integrative Structural Cell Biology

Ariane Briegel
Publications
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2025Evolutionary plasticity and functional repurposing of the essential metabolic enzyme MoeA., Commun Biol 2025 Jan; 8(1): 49.
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2024Communication between DNA polymerases and Replication Protein A within the archaeal replisome., Nat Commun 2024 Dec; 15(1): 10926.
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2024Dynamic interplay between a TonB-dependent heme transporter and a TonB protein in a membrane environment, mBio, In press, pp.e0178124. ⟨10.1128/mbio.01781-24⟩.
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2024Molecular mechanism of a triazole-containing inhibitor of Mycobacterium tuberculosis DNA gyrase., iScience 2024 Oct; 27(10): 110967.
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2024Corynebacterium glutamicum pyruvate:quinone oxidoreductase: an enigmatic metabolic enzyme with unusual structural features, FEBS Journal, In press, ⟨10.1111/febs.17232⟩.
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2024Identifying small-molecules binding sites in RNA conformational ensembles with SHAMAN., Nat Commun 2024 Jul; 15(1): 5725.
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2024Structure and Dynamics of Type 4a Pili and Type 2 Secretion System Endopili, In: Macromolecular Protein Complexes V, vol 104. Chapter 21. p549-563.
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2024A comprehensive dataset of protein-protein interactions and ligand binding pockets for advancing drug discovery, Scientific Data , 2024, 11 (1), pp.402. ⟨10.1038/s41597-024-03233-z⟩.
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2024Insights from structure-activity relationships and the binding mode of peptidic α-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1., Eur J Med Chem 2024 Apr; 269(): 116308.
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2024Mechanism of action of phthalazinone derivatives against rabies virus., Antiviral Res 2024 Apr; 224(): 105838.
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