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  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinician Researcher
  • Department Manager
  • Full Professor
  • Graduate Student
  • Honorary Professor
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Prize
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
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© Olivier Sperandio
Xray crystal structure (PDB 1YCR) of tumor suppressor p53 (green) bound to MDM2 (magenta), Image carried out using QuteMole v0.4.1

Projects

Project
Ongoing
11 Members

Energir: Energy dependent iron import by Gram-negative bacteria

Nadia Izadi-Pruneyre (PI)

Gram-negative bacteria are delimited by an envelope composed of two membranes (the outer and the inner-membranes) separated by the periplasmic space. This envelope includes macromolecular machines that ensure and regulate exchanges between the bacterium […]
Project
Ongoing
6 Members

TheraEPI

Paola Arimondo (PI)

A common phenomenon in most microbial infections is the attenuation of the host’s immediate immune response, allowing for long-term colonization. We and others have shown that many pathogens achieve this by manipulating the epigenetic […]
Project
Ongoing
4 Members

AntiBronchio

Olivier Sperandio (PI)

Design of Antiviral drugs for Bronchiolitis Virus using a novel therapeutic target.
Project
Ongoing
3 Members

TARGETBONE

Martine Cohen-Solal (PI)

New TARGETs for osteoporosis: from mesenchymal stem cells to the regulation of osteogenesis and BONE mass.
Project
Ongoing
2 Members

PPI-Chem

Olivier Sperandio (PI)

Protein-Protein Interactions (PPIs) are involved in most biological process and diseases. With a recently estimated number of 370,000 PPIs in humans, they constitute a large ‘reservoir’ for therapeutic development compared to ‘conventional’ drug targets. […]

Tools

Tool
Ongoing
7 Members

Chem-REST

Olivier Sperandio (PI)

This project aims at efficiently storing millions of unique molecular compounds along with some of their already calculated properties. The database named Chem-REST is able to deal with extensive sets of data: millions of […]
Tool
Ongoing
12 Members

iPPI-DB Initiative

Olivier Sperandio (PI)

In order to boost the identification of low-molecular-weight drugs on protein-protein interactions (PPI), it is essential to properly collect and annotate experimental data about successful examples. This provides the scientific community with the necessary […]

Publications

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