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2024Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models., Sci Transl Med 2024 Sep; 16(764): eado4463.
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2023Expedient synthesis of l-heptose derived septacidin building blocks from l-glucose, Carbohydr. Res. 2023, 534, 108985.
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2022The First-in-Human Synthetic Glycan-Based Conjugate Vaccine Candidate against Shigella., ACS Cent Sci 2022 Apr; 8(4): 449-460.
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2022Toward a Multivalent Synthetic Oligosaccharide-Based Conjugate Vaccine against Shigella: State-of-the-Art for a Monovalent Prototype and Challenges., Vaccines (Basel) 2022 Mar; 10(3): .
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2022Combination of High-Resolution Multistage Ion Mobility and Tandem MS with High Energy of Activation to Resolve the Structure of Complex Chemoenzymatically Synthesized Glycans., Anal Chem 2022 02; 94(4): 2279-2287.
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2021Computer-aided engineering of a branching sucrase for the glucodiversification of a tetrasaccharide precursor of S. flexneri antigenic oligosaccharides., Sci Rep 2021 10; 11(1): 20294.
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2021A Comparative Study on the Efficiency of Two Mycobacterium avium subsp. paratuberculosis (MAP)-Derived Lipopeptides of L3P and L5P as Capture Antigens in an In-House Milk ELISA Test., Vaccines (Basel) 2021 Sep; 9(9): .
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2021Multigram synthesis of an orthogonally-protected pentasaccharide for use as a glycan precursor in a Shigella flexneri 3a conjugate vaccine: application to a ready-for-conjugation decasaccharide, Org. Chem. Front..
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2021Safety and immunogenicity of a synthetic carbohydrate conjugate vaccine against Shigella flexneri 2a in healthy adult volunteers: a phase 1, dose-escalating, single-blind, randomised, placebo-controlled study., Lancet Infect Dis 2021 04; 21(4): 546-558.
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2021Exploratory N-Protecting Group Manipulation for the Total Synthesis of Zwitterionic Shigella sonnei Oligosaccharides., Chemistry 2021 Mar; 27(18): 5694-5711.
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2021Convergent Chemoenzymatic Strategy to Deliver a Diversity of Shigella flexneri Serotype-Specific O-Antigen Segments from a Unique Lightly Protected Tetrasaccharide Core., J Org Chem 2021 02; 86(3): 2058-2075.
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2021Redirecting substrate regioselectivity using engineered ΔN123-GBD-CD2 branching sucrases for the production of pentasaccharide repeating units of S. flexneri 3a, 4a and 4b haptens., Sci Rep 2021 01; 11(1): 2474.
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2021Engineering Synthetic Lipopeptide Antigen for Specific Detection of Mycobacterium avium subsp. paratuberculosis Infection., Front Vet Sci 2021 ; 8(): 637841.
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2021Interferon-γ Response of Mycobacterium avium subsp. paratuberculosis Infected Goats to Recombinant and Synthetic Mycobacterial Antigens., Front Vet Sci 2021 ; 8(): 645251.
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2020The fully synthetic glycopeptide MAG-Tn3 therapeutic vaccine induces tumor-specific cytotoxic antibodies in breast cancer patients., Cancer Immunol Immunother 2020 May; 69(5): 703-716.
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2019Cleaved CD31 as a target for in vivo molecular imaging of inflammation., Sci Rep 2019 Dec; 9(1): 19560.
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2019An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis, Sci Transl Med. 2019 Jul 10: Vol. 11, Issue 500, eaat1479 DOI: 10.1126/scitranslmed.aat1479 .
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2019An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis., Sci Transl Med 2019 Jul; 11(500): .
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2019Classical and novel strategies to develop a Shigella glycoconjugate vaccine: from concept to efficacy in human., Hum Vaccin Immunother 2019 ; 15(6): 1338-1356.
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2018ADP-heptose is a newly identified pathogen-associated molecular pattern of Shigella flexneri., EMBO Rep 2018 12; 19(12): .
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2018Bacteriophage Sf6 Tailspike Protein for Detection of Shigella flexneri Pathogens., Viruses 2018 08; 10(8): .
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2017Selection of similar single domain antibodies from two immune VHH libraries obtained from two alpacas by using different selection methods., Immunol Lett 2017 Aug; 188(): 89-95.
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2017Cell wall peptidolipids of Mycobacterium avium: from genetic prediction to exact structure of a nonribosomal peptide., Mol Microbiol 2017 Aug; 105(4): 525-539.
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2017Rearranged Biosynthetic Gene Cluster and Synthesis of Hassallidin E in Planktothrix serta PCC 8927, ACS Chem Biol 2017 Jul; 12(7): 1796-1804.
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2017Dirhamnolipids secreted from Pseudomonas aeruginosa modify anjpegungal susceptibility of Aspergillus fumigatus by inhibiting β1,3 glucan synthase activity., ISME J 2017 07; 11(7): 1578-1591.
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2017Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate, Organic & Biomolecular Chemistry, 2017, 15, 114 - 123.
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2017Chemically-defined camelid antibody bioconjugate for the magnetic resonance imaging of Alzheimer’s disease., MAbs 2017 ; 9(6): 1016-1027.
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2016Camelid single-domain antibodies: A versatile tool for in vivo imaging of extracellular and intracellular brain targets., J Control Release 2016 Dec; 243(): 1-10.
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2016Heparan sulfate differentially controls CXCL12α- and CXCL12γ-mediated cell migration through differential presentation to their receptor CXCR4, Sci Signal 2016 Nov;9(452):ra107.
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2016CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge, Sci Rep 2016 Oct;6:34829.
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2016Detailed Investigation of the Immunodominant Role of O-Antigen Stoichiometric O-Acetylation as Revealed by Chemical Synthesis, Immunochemistry, Solution Conformation and STD-NMR Spectroscopy for Shigella flexneri 3a, Chemistry 2016 Jul;22(31):10892-911.
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2016Efficient Iterative Synthesis of O-Acetylated Tri- to Pentadecasaccharides Related to the Lipopolysaccharide of Shigella flexneri Type 3 a through Di- and Trisaccharide Glycosyl Donors., Chem Asian J 2017 Feb; 12(4): 419-439.
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2016The fully synthetic MAG-Tn3 therapeutic vaccine containing the tetanus toxoid-derived TT830-844 universal epitope provides anti-tumor immunity., Cancer Immunol Immunother 2016 Mar; 65(3): 315-25.
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2016Seroreactivity against Specific L5P Antigen from Mycobacterium avium subsp. paratuberculosis in Children at Risk for T1D., PLoS One 2016 ; 11(6): e0157962.
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2015Programmed chemo-enzymatic synthesis of the oligosaccharide component of a carbohydrate-based antibacterial vaccine candidate, Chem. Commun. (Camb.) 2015 Feb;51(13):2581-4.
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2014Well-defined biomimetic surfaces to characterize glycosaminoglycan-mediated interactions on the molecular, supramolecular and cellular levels, Biomaterials 2014 Oct;35(32):8903-15.
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2013CGTase-catalysed cis-glucosylation of L-rhamnosides for the preparation of Shigella flexneri 2a and 3a haptens, Chembiochem 2014 Jan;15(2):293-300.
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2012Multidisciplinary approaches to study O-antigen:antibody recognition in support of the development of synthetic carbohydrate-based enteric vaccines, “Anticarbohydrate Antibodies - from molecular basis to clinical applications”, P. Kosma and S. Müller-Loennies Eds, Springer-Verlag GmbH, New York, Vienna 2012, pp 1-36.
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2011Direct inhibition of NF-κB activation by peptide targeting the NOA ubiquitin binding domain of NEMO, Biochem. Pharmacol. 2011 Nov;82(9):1163-74.
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2011Dynamic aspects of antibody:oligosaccharide complexes characterized by molecular dynamics simulations and saturation transfer difference nuclear magnetic resonance, Glycobiology 2011 Dec;21(12):1570-9.
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2011Peptidoglycan crosslinking relaxation plays an important role in Staphylococcus aureus WalKR-dependent cell viability, PLoS ONE 2011;6(2):e17054.
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2010Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant, Blood 2010 Nov;116(18):3526-36.
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