Timeline

Salah Mecheri
Group Leader
18 Nov 2019
event

PhD thesis defense Morgane Grand

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22 Aug 2017
publication

Immunological memory to blood-stage malaria infection is controlled by the histamine releasing factor (HRF) of the parasite

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09 Feb 2017
publication

The antimicrobial molecule trappin-2/elafin has anti-parasitic properties and is protective in vivo in a murine model of cerebral malaria

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23 Feb 2016
publication

Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites

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27 Jan 2016
project

Rodent and human malaria models to investigate host-parasite interactions central for malaria pathogenesis

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19 Jan 2016
team

Group : Salah Mecheri

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25 Aug 2015
publication

Risk factors associated with asthma, atopic dermatitis and rhinoconjunctivitis in a rural Senegalese cohort

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08 Jul 2015
project

P. berghei, a rodent malaria model to investigate host-parasite interactions central for malaria pathogenesis

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11 May 2015
team

Biology of Host-parasite Interactions

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27 Apr 2015
publication

Disruption of Parasite hmgb2 Gene Attenuates Plasmodium berghei ANKA Pathogenicity

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22 Nov 2014
publication

Plasmodium berghei histamine-releasing factor favours liver-stage development via inhibition of IL-6 production and associates with a severe outcome of disease

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26 Jul 2013
publication

Regulatory CD4+Foxp3+ T cells control the severity of anaphylaxis

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24 Sep 2012
publication

Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum

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22 Jun 2012
publication

Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging

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01 Jun 2012
publication

Impact of mosquito bites on asexual parasite density and gametocyte prevalence in asymptomatic chronic Plasmodium falciparum infections and correlation with IgE and IgG titers.

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16 Mar 2012
publication

Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells

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23 Dec 2011
publication

Duality and complexity of allergic type inflammatory mechanisms in determining the outcome of malaria disease

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03 Oct 2011
publication

Critical role of the neutrophil-associated high-affinity receptor for IgE in the pathogenesis of experimental cerebral malaria

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02 Jun 2011
publication

Downregulation of basophil-derived IL-4 and in vivo T(H)2 IgE responses by serotonin and other organic cation transporter 3 ligands

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11 Mar 2011
publication

Anopheles stephensi saliva enhances progression of cerebral malaria in a murine model

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23 Feb 2011
publication

Contribution of allergic inflammatory response to the pathogenesis of malaria disease

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30 Dec 2010
publication

Human and mouse mast cells express and secrete the GPI-anchored isoform of CD160

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03 Sep 2010
publication

Strain-transcendent immune response to recombinant Var2CSA DBL5-ε domain block P. falciparum adhesion to placenta-derived BeWo cells under flow conditions

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23 Jun 2009
publication

Histamine H(3) receptor-mediated signaling protects mice from cerebral malaria

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01 Apr 2009
publication

[Role of histamine and histamine receptors in the pathogenesis of malaria]

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28 Jan 2008
publication

Inhibition of histamine-mediated signaling confers significant protection against severe malaria in mouse models of disease

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04 Jan 2007
publication

Total and functional parasite specific IgE responses in Plasmodium falciparum-infected patients exhibiting different clinical status

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01 Apr 2006
publication

Mast cell-dependent down-regulation of antigen-specific immune responses by mosquito bites

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01 May 2005
publication

Comparison of the allergenic potency of spores and mycelium of Cladosporium

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01 Apr 2005
publication

Anopheles mosquito bites activate cutaneous mast cells leading to a local inflammatory response and lymph node hyperplasia

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01 Aug 2004
publication

Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects

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01 Oct 2003
publication

Human serum IgE-mediated mast cell degranulation shows poor correlation to allergen-specific IgE content

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01 May 2003
publication

[Immunological and non immunological mechanisms in urticaria]

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15 Mar 2003
publication

Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo

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01 Sep 2002
publication

Immunoregulatory properties of mast cell-derived exosomes

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01 Feb 2001
publication

Capacity of mouse mast cells to prime T cells and to induce specific antibody responses in vivo

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15 Jan 2001
publication

Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes

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01 Jan 2001
publication

Nonspecific B and T cell-stimulatory activity mediated by mast cells is associated with exosomes

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01 Jan 2000
publication

In vitro and in vivo immunostimulatory potential of bone marrow-derived mast cells on B- and T-lymphocyte activation

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01 Jun 1999
publication

FcepsilonRI-mediated antigen endocytosis turns interferon-gamma-treated mouse mast cells from inefficient into potent antigen-presenting cells

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01 Dec 1998
publication

Expression of functional major histocompatibility complex class II molecules on HMC-1 human mast cells

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01 Jul 1998
publication

Specific antigen targeting to surface IgE and IgG on mouse bone marrow-derived mast cells enhances efficiency of antigen presentation

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01 Mar 1998
publication

IL-4 mRNA transcription is induced in mouse bone marrow-derived mast cells through an MHC class II-dependent signaling pathway

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01 Dec 1997
publication

Accumulation of major histocompatibility complex class II molecules in mast cell secretory granules and their release upon degranulation

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01 Jun 1997
publication

Functional analysis of Mycoplasma arthritidis-derived mitogen interactions with class II molecules

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01 May 1997
publication

Unravelling the mast cell dilemma: culprit or victim of its generosity?

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01 Oct 1996
publication

Exogenous and endogenous antigens are differentially presented by mast cells to CD4+ T lymphocytes

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15 Aug 1996
publication

Mouse bone marrow-derived mast cells and mast cell lines constitutively produce B cell growth and differentiation activities

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01 Jun 1995
publication

Presentation of soluble antigens by mast cells: upregulation by interleukin-4 and granulocyte/macrophage colony-stimulating factor and downregulation by interferon-gamma

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01 Nov 1994
publication

Modulation of Mycoplasma arthritidis-derived superantigen-induced cytokine gene expression by dexamethasone and interleukin-4

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01 Jun 1994
publication

Mycoplasma arthritidis-derived superantigen induces proinflammatory monokine gene expression in the THP-1 human monocytic cell line

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01 Dec 1993
publication

Antigen-dependent stimulation by bone marrow-derived mast cells of MHC class II-restricted T cell hybridoma

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01 Apr 1993
publication

Anti-histone autoantibodies react specifically with the B cell surface

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01 Jan 1993
publication

Characterization of anergy to the superantigen Staphylococcus enterotoxin B

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01 Jan 1993
publication

Differential expression of T cell receptor variable beta genes on CD4+ and CD8+ T cells: influence by sex linked genes?

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01 Dec 1992
publication

A stimulatory Mls-1 superantigen is destroyed by ultraviolet light while other Mtv-7 antigens remain intact. Significance for Mls-1 unresponsiveness

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01 Oct 1992
publication

Regulation of T cell function by Mtv-7 gene products

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01 Oct 1992
publication

Interleukin-2 may enhance or inhibit antibody production by B cells depending on intracellular cAMP concentrations

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01 Jun 1992
publication

In vivo presentation of Mls-1 antigen by T and B lymphocytes

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01 Dec 1991
publication

B cells control the aggregability of CD4 on T cells through continuous physical interactions

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01 Nov 1991
publication

Induction of neonatal tolerance to the Mls-1a self-super-antigen. Time kinetics and MHC restriction

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01 Apr 1991
publication

A characteristic Mls-1a response precedes Mls-1a anergy in vivo

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01 Apr 1991
publication

Does interleukin-1 save B cells from paralysis? Studies with pre-B cells and antigen-reactive B cells

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15 Feb 1990
publication

Immunogenic peptides require an undisturbed phospholipid cell membrane environment and must be amphipathic to immobilize Ia on B cells

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15 Feb 1990
publication

Immunogenic Ia-binding peptides immobilize the Ia molecule and facilitate its aggregation on the B cell membrane. Control by the M1s-1 gene

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01 Jan 1989
publication

Release of allergens from Cladosporium conidia

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15 Nov 1988
publication

Study of the epitope structure of purified Dac G I and Lol p I, the major allergens of Dactylis glomerata and Lolium perenne pollens, using monoclonal antibodies

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01 May 1988
publication

Demonstration of idiotypes expressed on basophil-bound IgE antibodies by using anti-idiotype-induced histamine release in grass pollen-allergic patients

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01 Mar 1987
publication

Biological effect of transferrin on mast cell mediator release during the passive cutaneous anaphylaxis reaction: a possible inhibition mechanism involving iron

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01 Mar 1985
publication

Production of a monoclonal antibody against a major allergen of Dactylis glomerata pollen (Dg1)

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01 Jan 1985
publication

Purification and characterization of a major allergen from Dactylis glomerata pollen: the Ag Dg1

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01 Jan 1985
publication

Induction of a passive cutaneous anaphylaxis inhibitory factor in mice

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01 Jan 1984
publication

Presence of IL 1 activity in the supernatant of human monocytes challenged with purified allergenic constituents

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01 May 1983
publication

Inhibition of the passive cutaneous anaphylaxis reaction to Dactylis glomerata pollen allergens by a purified component of this pollen

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01 Jan 1983
publication

Relationship between cytidine 5’diphosphocholine epitope density on ovalbumin and IgE antibody responses compared to other isotypes

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01 Nov 1975
publication

Responses to drug therapy in ulcerative colitis. Evaluation by rectal biopsy and histopathological changes

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