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© Artur Scherf
Scanning Electron Microscopy of Red Blood Cell infected by Plasmodium falciparum.
Publication : International archives of allergy and applied immunology

Release of allergens from Cladosporium conidia

Team: Biology of Host-parasite Interactions
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in International archives of allergy and applied immunology - 01 Jan 1989

Bouziane H, Latgé JP, Mecheri S, Fitting C, Prévost MC

Link to Pubmed [PMID] – 2722254

Int. Arch. Allergy Appl. Immunol. 1989;88(3):261-6

Sugars and proteins are released from conidia of Cladosporium cladosporioides after incubation in various chemical solutions. Ultrastructural studies demonstrated that these exudates contained components from the outer wall layer and from internal compartments (inner wall and cytoplasm). The allergenicity of the extracts was evaluated using a passive cutaneous anaphylaxis test and radioallergosorbent test. Spore exudates obtained with Tris, NaOH or NaCl displayed the highest allergenic potency. The amount of allergens released was dependent on the incubation media, on the extraction time and on the spore concentration.