Timeline

Pedro Escoll

Group Leader

11 Sep 2024

publication

The unique Legionella longbeachae capsule favors intracellular replication and immune evasion.

24 Jan 2024

project

Description des voies métaboliques perturbées au cours d’infections par des bactéries intracellulaires : METABACT (2023-042)

12 Jan 2024

project

Interaction entre les bactéries et les mitochondries intracellulaires au cours des infections par Legionella Pneumophila et Salmonella Typhimurium : MITOBACT

09 Dec 2023

publication

Leptospiral lipopolysaccharide dampens inflammation through upregulation of autophagy adaptor p62 and NRF2 signaling in macrophages.

17 Mar 2023

publication

High-content assay to measure mitochondrial function and bacterial vacuole size in infected human primary macrophages.

01 Jan 2023

publication

Legionella and mitochondria, an intriguing relationship.

15 Sep 2022

publication

Chromosome-scale assemblies of Acanthamoeba castellanii genomes provide insights into Legionella pneumophila infection-related chromatin reorganization.

23 Jun 2022

project

Predicting single-cell fate during infection using machine learning

23 Jun 2022

project

Metabolic Host-Pathogen Interactions: Revealing how Intracellular Bacteria hijack Mitochondrial OXPHOS during Infection (ANR JCJC 2021)

23 Jun 2022

project

INNOV-10-19 – Mitochondrial Electron Transport Chain complexes: new targets to tackle infection by intracellular bacteria? (DARRI/Institut Carnot)

28 Mar 2022

team

Metabolic host-bacteria interactions

18 Feb 2022

news

Legionellosis: a novel mechanism by which the bacterium Legionella pneumophila regulates the immune response of its host cells

09 Feb 2022

publication

Translocated Legionella pneumophila small RNAs mimic eukaryotic microRNAs targeting the host immune response.

13 Jan 2022

news

The bacterium causing legionellosis modifies the electrochemical potential of host mitochondria to better replicate

01 Jan 2022

publication

Alive Pathogenic and Saprophytic Leptospires Enter and Exit Human and Mouse Macrophages With No Intracellular Replication.

09 Dec 2021

publication

Reverting the mode of action of the mitochondrial F O F 1-ATPase by Legionella pneumophila preserves its replication niche

22 Oct 2021

publication

Dichotomous metabolic networks govern human ILC2 proliferation and function.

24 May 2020

publication

Danger-associated Metabolic Modifications During Bacterial Infection of Macrophages

24 Jan 2020

publication

Legionnaires’ Disease: State of the Art Knowledge of Pathogenesis Mechanisms of Legionella.

08 Jan 2020

event

Soutenance HDR “Immunometabolic interactions of human cells and intracellular bacteria: a new way to tackle infection” – Département Microbiologie – Pedro Escoll Guerrero

30 Aug 2019

publication

Roles of Mitochondrial Respiratory Complexes during Infection

24 Jun 2019

publication

Metabolic reprogramming: an innate cellular defence mechanism against intracellular bacteria?

01 Jan 2019

publication

Mitochondrial Dynamics and Activity in Legionella-Infected Cells

14 Apr 2018

publication

Metabolic reprogramming of host cells upon bacterial infection: Why shift to a Warburg-like metabolism?

07 Nov 2017

publication

Legionella pneumophila CsrA regulates a metabolic switch from amino acid to glycerolipid metabolism.

13 Sep 2017

publication

Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages.

06 Sep 2017

publication

Manipulation of Autophagy by Bacterial Pathogens Impacts Host Immunity

27 Dec 2016

publication

MAMs are attractive targets for bacterial repurposing of the host cell: MAM-functions might be key for undermining an infected cell

08 Dec 2016

publication

Legionella longbeachae is immunologically silent and highly virulent in vivo

18 May 2016

publication

Legionella pneumophila restrains autophagy by modulating the host’s sphingolipid metabolism

03 Mar 2016

publication

Modulation of Host Autophagy during Bacterial Infection: Sabotaging Host Munitions for Pathogen Nutrition

03 Feb 2016

news

Legionella pneumophila: identification of a new strategy to counteract the antibacterial response of the host cell

01 Feb 2016

publication

Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy

01 Jan 2016

publication

Targeting of host organelles by pathogenic bacteria: a sophisticated subversion strategy

11 May 2015

team

Biology Of Intracellular Bacteria

22 Apr 2015

publication

Sustained interleukin-1β exposure modulates multiple steps in glucocorticoid receptor signaling, promoting split-resistance to the transactivation of prominent anti-inflammatory genes by glucocorticoids

13 Nov 2014

publication

TLR9 activation is triggered by the excess of stimulatory versus inhibitory motifs present in Trypanosomatidae DNA

01 Jul 2014

publication

Neuronal injury external to the retina rapidly activates retinal glia, followed by elevation of markers for cell cycle re-entry and death in retinal ganglion cells

01 Jan 2013

publication

From amoeba to macrophages: exploring the molecular mechanisms of Legionella pneumophila infection in both hosts.

15 Mar 2010

publication

Ordering human CD34+CD10-CD19+ pre/pro-B-cell and CD19- common lymphoid progenitor stages in two pro-B-cell development pathways

14 Dec 2009

publication

Somatic tetraploidy in specific chick retinal ganglion cells induced by nerve growth factor

01 Mar 2005

publication

Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4

01 Jun 2004

publication

Nitric oxide activates the expression of IRAK-M via the release of TNF-alpha in human monocytes

14 Nov 2003

publication

A little guide for advanced search:

The unique Legionella longbeachae capsule favors intracellular replication and immune evasion.

Description des voies métaboliques perturbées au cours d’infections par des bactéries intracellulaires : METABACT (2023-042)

Interaction entre les bactéries et les mitochondries intracellulaires au cours des infections par Legionella Pneumophila et Salmonella Typhimurium : MITOBACT

Leptospiral lipopolysaccharide dampens inflammation through upregulation of autophagy adaptor p62 and NRF2 signaling in macrophages.

High-content assay to measure mitochondrial function and bacterial vacuole size in infected human primary macrophages.

Legionella and mitochondria, an intriguing relationship.

Chromosome-scale assemblies of Acanthamoeba castellanii genomes provide insights into Legionella pneumophila infection-related chromatin reorganization.

Predicting single-cell fate during infection using machine learning

Metabolic Host-Pathogen Interactions: Revealing how Intracellular Bacteria hijack Mitochondrial OXPHOS during Infection (ANR JCJC 2021)

INNOV-10-19 – Mitochondrial Electron Transport Chain complexes: new targets to tackle infection by intracellular bacteria? (DARRI/Institut Carnot)

Metabolic host-bacteria interactions

Legionellosis: a novel mechanism by which the bacterium Legionella pneumophila regulates the immune response of its host cells

Translocated Legionella pneumophila small RNAs mimic eukaryotic microRNAs targeting the host immune response.

The bacterium causing legionellosis modifies the electrochemical potential of host mitochondria to better replicate

Alive Pathogenic and Saprophytic Leptospires Enter and Exit Human and Mouse Macrophages With No Intracellular Replication.

Reverting the mode of action of the mitochondrial F O F 1-ATPase by Legionella pneumophila preserves its replication niche

Dichotomous metabolic networks govern human ILC2 proliferation and function.

Danger-associated Metabolic Modifications During Bacterial Infection of Macrophages

Legionnaires’ Disease: State of the Art Knowledge of Pathogenesis Mechanisms of Legionella.

Soutenance HDR “Immunometabolic interactions of human cells and intracellular bacteria: a new way to tackle infection” – Département Microbiologie – Pedro Escoll Guerrero

Roles of Mitochondrial Respiratory Complexes during Infection

Metabolic reprogramming: an innate cellular defence mechanism against intracellular bacteria?

Mitochondrial Dynamics and Activity in Legionella-Infected Cells

Metabolic reprogramming of host cells upon bacterial infection: Why shift to a Warburg-like metabolism?

Legionella pneumophila CsrA regulates a metabolic switch from amino acid to glycerolipid metabolism.

Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages.

Manipulation of Autophagy by Bacterial Pathogens Impacts Host Immunity

MAMs are attractive targets for bacterial repurposing of the host cell: MAM-functions might be key for undermining an infected cell

Legionella longbeachae is immunologically silent and highly virulent in vivo

Legionella pneumophila restrains autophagy by modulating the host’s sphingolipid metabolism

Modulation of Host Autophagy during Bacterial Infection: Sabotaging Host Munitions for Pathogen Nutrition

Legionella pneumophila: identification of a new strategy to counteract the antibacterial response of the host cell

Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy

Targeting of host organelles by pathogenic bacteria: a sophisticated subversion strategy

Biology Of Intracellular Bacteria

Sustained interleukin-1β exposure modulates multiple steps in glucocorticoid receptor signaling, promoting split-resistance to the transactivation of prominent anti-inflammatory genes by glucocorticoids

TLR9 activation is triggered by the excess of stimulatory versus inhibitory motifs present in Trypanosomatidae DNA

Neuronal injury external to the retina rapidly activates retinal glia, followed by elevation of markers for cell cycle re-entry and death in retinal ganglion cells

From amoeba to macrophages: exploring the molecular mechanisms of Legionella pneumophila infection in both hosts.

Ordering human CD34+CD10-CD19+ pre/pro-B-cell and CD19- common lymphoid progenitor stages in two pro-B-cell development pathways

Somatic tetraploidy in specific chick retinal ganglion cells induced by nerve growth factor

Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4

Nitric oxide activates the expression of IRAK-M via the release of TNF-alpha in human monocytes

Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients