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  • 2025
    Debashis Dhara, Laurence A. Mulard, and Marcel Hollenstein*, Natural, modified and conjugated carbohydratesin nucleic acids, Chem. Soc. Rev. 2025, 54, 2948-2983.
  • 2023
    Debashis Dhara, Laurence A. Mulard,* Marcel Hollenstein*, Expedient synthesis of l-heptose derived septacidin building blocks from l-glucose, Carbohydr. Res. 2023, 534, 108985.
  • 2022
    van der Put RMF, Smitsman C, de Haan A, Hamzink M, Timmermans H, Uittenbogaard J, Westdijk J, Stork M, Ophorst O, Thouron F, Guerreiro C, Sansonetti PJ, Phalipon A, Mulard LA, , The First-in-Human Synthetic Glycan-Based Conjugate Vaccine Candidate against Shigella., ACS Cent Sci 2022 Apr; 8(4): 449-460.
  • 2022
    Phalipon A, Mulard LA, , Toward a Multivalent Synthetic Oligosaccharide-Based Conjugate Vaccine against Shigella: State-of-the-Art for a Monovalent Prototype and Challenges., Vaccines (Basel) 2022 Mar; 10(3): .
  • 2022
    Ropartz D, Fanuel M, Ollivier S, Lissarrague A, Benkoulouche M, Mulard LA, André I, Guieysse D, Rogniaux H, , Combination of High-Resolution Multistage Ion Mobility and Tandem MS with High Energy of Activation to Resolve the Structure of Complex Chemoenzymatically Synthesized Glycans., Anal Chem 2022 02; 94(4): 2279-2287.
  • 2021
    Benkoulouche M, Ben Imeddourene A, Barel LA, Lefebvre D, Fanuel M, Rogniaux H, Ropartz D, Barbe S, Guieysse D, Mulard LA, Remaud-Siméon M, Moulis C, André I, , Computer-aided engineering of a branching sucrase for the glucodiversification of a tetrasaccharide precursor of S. flexneri antigenic oligosaccharides., Sci Rep 2021 10; 11(1): 20294.
  • 2021
    , Multigram synthesis of an orthogonally-protected pentasaccharide for use as a glycan precursor in a Shigella flexneri 3a conjugate vaccine: application to a ready-for-conjugation decasaccharide, Org. Chem. Front..
  • 2021
    Cohen D, Atsmon J, Artaud C, Meron-Sudai S, Gougeon ML, Bialik A, Goren S, Asato V, Ariel-Cohen O, Reizis A, Dorman A, Hoitink CWG, Westdijk J, Ashkenazi S, Sansonetti P, Mulard LA, Phalipon A, , Safety and immunogenicity of a synthetic carbohydrate conjugate vaccine against Shigella flexneri 2a in healthy adult volunteers: a phase 1, dose-escalating, single-blind, randomised, placebo-controlled study., Lancet Infect Dis 2021 04; 21(4): 546-558.
  • 2021
    Dhara D, Mulard LA, , Exploratory N-Protecting Group Manipulation for the Total Synthesis of Zwitterionic Shigella sonnei Oligosaccharides., Chemistry 2021 Mar; 27(18): 5694-5711.
  • 2021
    Hu Z, Benkoulouche M, Barel LA, Le Heiget G, Ben Imeddourene A, Le Guen Y, Monties N, Guerreiro C, Remaud-Siméon M, Moulis C, André I, Mulard LA, , Convergent Chemoenzymatic Strategy to Deliver a Diversity of Shigella flexneri Serotype-Specific O-Antigen Segments from a Unique Lightly Protected Tetrasaccharide Core., J Org Chem 2021 02; 86(3): 2058-2075.
  • 2021
    Benkoulouche M, Ben Imeddourene A, Barel LA, Le Heiget G, Pizzut S, Kulyk H, Bellvert F, Bozonnet S, Mulard LA, Remaud-Siméon M, Moulis C, André I, , Redirecting substrate regioselectivity using engineered ΔN123-GBD-CD2 branching sucrases for the production of pentasaccharide repeating units of S. flexneri 3a, 4a and 4b haptens., Sci Rep 2021 01; 11(1): 2474.
  • 2019
    Barel LA, Mulard LA, , Classical and novel strategies to develop a Shigella glycoconjugate vaccine: from concept to efficacy in human., Hum Vaccin Immunother 2019 ; 15(6): 1338-1356.
  • 2018
    García-Weber D, Dangeard AS, Cornil J, Thai L, Rytter H, Zamyatina A, Mulard LA, Arrieumerlou C, , ADP-heptose is a newly identified pathogen-associated molecular pattern of Shigella flexneri., EMBO Rep 2018 12; 19(12): .
  • 2018
    Kunstmann S, Scheidt T, Buchwald S, Helm A, Mulard LA, Fruth A, Barbirz S, , Bacteriophage Sf6 Tailspike Protein for Detection of Shigella flexneri Pathogens., Viruses 2018 08; 10(8): .
  • 2017
    Briard B, Rasoldier V, Bomme P, ElAouad N, Guerreiro C, Chassagne P, Muszkieta L, Latgé JP, Mulard L, Beauvais A, , Dirhamnolipids secreted from Pseudomonas aeruginosa modify anjpegungal susceptibility of Aspergillus fumigatus by inhibiting β1,3 glucan synthase activity., ISME J 2017 07; 11(7): 1578-1591.
  • 2016
    Boutet J, Blasco P, Guerreiro C, Thouron F, Dartevelle S, Nato F, Cañada FJ, Ardá A, Phalipon A, Jiménez-Barbero J, Mulard LA, Detailed Investigation of the Immunodominant Role of O-Antigen Stoichiometric O-Acetylation as Revealed by Chemical Synthesis, Immunochemistry, Solution Conformation and STD-NMR Spectroscopy for Shigella flexneri 3a, Chemistry 2016 Jul;22(31):10892-911.
  • 2016
    Hu Z, Bongat White AF, Mulard LA, , Efficient Iterative Synthesis of O-Acetylated Tri- to Pentadecasaccharides Related to the Lipopolysaccharide of Shigella flexneri Type 3 a through Di- and Trisaccharide Glycosyl Donors., Chem Asian J 2017 Feb; 12(4): 419-439.
  • 2016
    van der Put RM, Kim TH, Guerreiro C, Thouron F, Hoogerhout P, Sansonetti PJ, Westdijk J, Stork M, Phalipon A, Mulard LA, A Synthetic Carbohydrate Conjugate Vaccine Candidate against Shigellosis: Improved Bioconjugation and Impact of Alum on Immunogenicity, Bioconjug. Chem. 2016 Mar;.
  • 2015
    Salamone S, Guerreiro C, Cambon E, Hargreaves JM, Tarrat N, Remaud-Siméon M, André I, Mulard LA, Investigation on the synthesis of Shigella flexneri-specific oligosaccharides using disaccharides as potential transglucosylase acceptor substrates, J. Org. Chem. 2015 Sep;.
  • 2015
    Salamone S, Guerreiro C, Cambon E, André I, Remaud-Siméon M, Mulard LA, Programmed chemo-enzymatic synthesis of the oligosaccharide component of a carbohydrate-based antibacterial vaccine candidate, Chem. Commun. (Camb.) 2015 Feb;51(13):2581-4.
  • 2015
    Vergès A, Cambon E, Barbe S, Salamone S, Le Guen Y, Moulis C, Mulard LA, Remaud-Siméon M, André I, Computer-aided design of sequence libraries for the engineering of transglucosylase binding subsites to enable glucosylation of an unnatural disaccharide motif of relevance for bacterial antigen synthesis, ACS Catalysis 2015, 5, 1186-98.
  • 2014
    Pfister HB, Mulard LA, Synthesis of the zwitterionic repeating unit of the O-antigen from Shigella sonnei and chain elongation at both ends, Org. Lett. 2014 Sep;16(18):4892-5.
  • 2014
    Hargreaves JM, Le Guen Y, Guerreiro C, Descroix K, Mulard LA, Linear synthesis of the branched pentasaccharide repeats of O-antigens from Shigella flexneri 1a and 1b demonstrating the major steric hindrance associated with type-specific glucosylation, Org. Biomol. Chem. 2014 Oct;12(39):7728-49.
  • 2014
    Gauthier C, Chassagne P, Theillet FX, Guerreiro C, Thouron F, Nato F, Delepierre M, Sansonetti PJ, Phalipon A, Mulard LA, Non-stoichiometric O-acetylation of Shigella flexneri 2a O-specific polysaccharide: synthesis and antigenicity, Org. Biomol. Chem. 2014 Jun;12(24):4218-32.
  • 2013
    Urbach C, Halila S, Guerreiro C, Driguez H, Mulard LA, Armand S, CGTase-catalysed cis-glucosylation of L-rhamnosides for the preparation of Shigella flexneri 2a and 3a haptens, Chembiochem 2014 Jan;15(2):293-300.
  • 2013
    Chassagne P, Raibaut L, Guerreiro C, Mulard LA, Concise synthesis of di- and trisaccharides related to the O-antigens from Shigella flexneri serotypes 6 and 6a, based on late stage mono-O-acetylation and/or site-selective oxydation, Tetrahedron 2013; 69:10337-50.
  • 2013
    Chassagne P, Fontana C, Guerreiro C, Gauthier C, Phalipon, A, Widmalm G, Mulard LA, Structural studies of the O-acetyl containing O-antigen from a Shigella flexneri serotype 6 strain and synthesis of oligosaccharide fragments thereof, Eur. J. Org. Chem. 2013, 4085–106.
  • 2012
    Champion E, Guérin F, Moulis C, Barbe S, Tran TH, Morel S, Descroix K, Monsan P, Mourey L, Mulard LA, Tranier S, Remaud-Siméon M, André I, Applying pairwise combinations of amino acid mutations for sorting out highly efficient glucosylation tools for chemo-enzymatic synthesis of bacterial oligosaccharides, J. Am. Chem. Soc. 2012 Nov;134(45):18677-88.
  • 2012
    Coïc YM, Baleux F, Poyraz Ö, Thibeaux R, Labruyere E, Chretien F, Sobhani I, Lazure T, Wyplosz B, Schneider G, Mulard L, Sansonetti PJ, Marteyn BS, Design of a specific colonic mucus marker using a human commensal bacterium cell surface domain, J. Biol. Chem. 2012 May;287(19):15916-22.
  • 2012
    Theillet FX, Chassagne P, Delepierre M, Phalipon A, Mulard LA , Multidisciplinary approaches to study O-antigen:antibody recognition in support of the development of synthetic carbohydrate-based enteric vaccines, “Anticarbohydrate Antibodies - from molecular basis to clinical applications”, P. Kosma and S. Müller-Loennies Eds, Springer-Verlag GmbH, New York, Vienna 2012, pp 1-36.
  • 2011
    Theillet FX, Frank M, Vulliez-Le Normand B, Simenel C, Hoos S, Chaffotte A, Bélot F, Guerreiro C, Nato F, Phalipon A, Mulard LA, Delepierre M, Dynamic aspects of antibody:oligosaccharide complexes characterized by molecular dynamics simulations and saturation transfer difference nuclear magnetic resonance, Glycobiology 2011 Dec;21(12):1570-9.
  • 2010
    Theillet FX, Simenel C, Guerreiro C, Phalipon A, Mulard LA, Delepierre M, Effects of backbone substitutions on the conformational behavior of Shigella flexneri O-antigens: implications for vaccine strategy, Glycobiology 2011 Jan;21(1):109-21.
  • 2010
    Champion E, Moulis C, Morel S, Mulard LA, Monsan P, Remaud-Siméon M, André I, A pH-based high-throughput screening of sucrose-utilizing transglucosidases for the development of novel enzymatic glucosylation tools, ChemCatChem 2010; 2: 969-75.
  • 2009
    Mulard LA, Phalipon A, From epitope characterization to the design of semi-synthetic glycoconjugate vaccines against Shigella flexneri 2a infection, ACS Symp Ser No. 989, R. Roy Ed, American Chemical Society, Washington, DC, USA 2009, pp 105-136.
  • 2009
    Said Hassane F, Phalipon A, Tanguy M, Guerreiro C, Bélot F, Frisch B, Mulard LA, Schuber F, Rational design and immunogenicity of liposome-based diepitope constructs: application to synthetic oligosaccharides mimicking the Shigella flexneri 2a O-antigen, Vaccine 2009 Aug;27(39):5419-26.
  • 2009
    Champion E, André I, Moulis C, Boutet J, Descroix K, Morel S, Monsan P, Mulard LA, Remaud-Siméon M, Design of alpha-transglucosidases of controlled specificity for programmed chemoenzymatic synthesis of antigenic oligosaccharides, J. Am. Chem. Soc. 2009 Jun;131(21):7379-89.
  • 2009
    Boutet J, Guerreiro C, Mulard LA, Efficient synthesis of six tri- to hexasaccharide fragments of Shigella flexneri serotypes 3a and/or X O-antigen, including a study on acceptors containing N-trichloroacetylglucosamine versus N-acetylglucosamine, J. Org. Chem. 2009 Apr;74(7):2651-70.
  • 2009
    Theillet FX, Saul FA, Vulliez-Le Normand B, Hoos S, Felici F, Weintraub A, Mulard LA, Phalipon A, Delepierre M, Bentley GA, Structural mimicry of O-antigen by a peptide revealed in a complex with an antibody raised against Shigella flexneri serotype 2a, J. Mol. Biol. 2009 May;388(4):839-50.
  • 2009
    Champion C, André I, Mulard LA, Monsan P, Remaud-Siméon M, Morel S, Synthesis of L-rhamnose and N-acetyl-D-glucosamine derivatives with glucansucrases, J. Carbohydr. Chem. 2009; 28: 142-60.
  • 2009
    Phalipon A, Tanguy M, Grandjean C, Guerreiro C, Bélot F, Cohen D, Sansonetti PJ, Mulard LA, A synthetic carbohydrate-protein conjugate vaccine candidate against Shigella flexneri 2a infection, J. Immunol. 2009 Feb;182(4):2241-7.
  • 2008
    Boutet J, Mulard LA, Synthesis of 2 tetra- and 4 pentasaccharide fragments of Shigella flexneri serotypes 3a and/or X O-antigens from a common tetrasaccharide intermediate, Eur. J. Org. Chem. 2008: 5526–5542.
  • 2008
    Boutet J, Guerreiro C, Mulard LA, Synthesis of branched tri- to pentasaccharides representative of fragments of Shigella flexneri serotypes 3a and/or X O-antigens, Tetrahedron 2008; 64: 10558-72.
  • 2008
    Grandjean C, Boutonnier A, Dassy B, Fournier JM, Mulard LA, Investigation towards bivalent chemically defined glycoconjugate immunogens prepared from acid-detoxified lipopolysaccharide of Vibrio cholerae O1, serotype Inaba, Glycoconj. J. 2009 Jan;26(1):41-55.
  • 2008
    Phalipon A, Mulard LA, Sansonetti PJ, Vaccination against shigellosis: is it the path that is difficult or is it the difficult that is the path?, Microbes Infect. 2008 Jul;10(9):1057-62.
  • 2008
    Vulliez-Le Normand B, Saul FA, Phalipon A, Bélot F, Guerreiro C, Mulard LA, Bentley GA, Structures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibody, Proc. Natl. Acad. Sci. U.S.A. 2008 Jul;105(29):9976-81.
  • 2008
    Boutet, J.; Kim, T. H.; Guerreiro, C.; Mulard, L. A., Efficient route to orthogonally protected precursors of 2-acylamino-2-deoxy-3-O-substituted--D-glucopyranose derivatives and use thereof, Tetrahedron Lett. 2008; 49: 5339-42.
  • 2008
    Topalis D, Alvarez K, Barral K, Munier-Lehmann H, Schneider B, Véron M, Guerreiro C, Mulard L, El-Amri C, Canard B, Deville-Bonne D, Acyclic phosphonate nucleotides and human adenylate kinases: impact of a borano group on alpha-P position, Nucleosides Nucleotides Nucleic Acids 2008 Apr;27(4):319-31.
  • 2007
    Mulard L, [Carbohydrates and vaccines: from purified polysaccharides to semi-synthetic glycoconjugate vaccines], Ann Pharm Fr 2007 Jan;65(1):14-32.
  • 2006
    Phalipon A, Costachel C, Grandjean C, Thuizat A, Guerreiro C, Tanguy M, Nato F, Vulliez-Le Normand B, Bélot F, Wright K, Marcel-Peyre V, Sansonetti PJ, Mulard LA, Characterization of functional oligosaccharide mimics of the Shigella flexneri serotype 2a O-antigen: implications for the development of a chemically defined glycoconjugate vaccine, J. Immunol. 2006 Feb;176(3):1686-94.
  • 2005
    Clément MJ, Fortuné A, Phalipon A, Marcel-Peyre V, Simenel C, Imberty A, Delepierre M, Mulard LA, Toward a better understanding of the basis of the molecular mimicry of polysaccharide antigens by peptides: the example of Shigella flexneri 5a, J. Biol. Chem. 2006 Jan;281(4):2317-32.
  • 2005
    Grandjean C, Boutonnier A, Guerreiro C, Fournier JM, Mulard LA, On the preparation of carbohydrate-protein conjugates using the traceless Staudinger ligation, J. Org. Chem. 2005 Sep;70(18):7123-32.
  • 2005
    Matamoros T, Deval J, Guerreiro C, Mulard L, Canard B, Menéndez-Arias L, Suppression of multidrug-resistant HIV-1 reverse transcriptase primer unblocking activity by alpha-phosphate-modified thymidine analogues, J. Mol. Biol. 2005 Jun;349(3):451-63.
  • 2005
    Bélot F, Guerreiro C, Baleux F, Mulard LA, Synthesis of two linear PADRE conjugates bearing a deca- or pentadecasaccharide B epitope as potential synthetic vaccines against Shigella flexneri serotype 2a infection, Chemistry 2005 Feb;11(5):1625-35.
  • 2005
    Alvarez K, Deval J, Selmi B, Barral K, Boretto J, Guerreiro C, Mulard L, Sarfati R, Canard B, Borano-nucleotides: new analogues to circumvent HIV-1 RT-mediated nucleoside drug-resistance, Nucleosides Nucleotides Nucleic Acids 2005;24(5-7):419-21.
  • 2004
    Deval J, Alvarez K, Selmi B, Bermond M, Boretto J, Guerreiro C, Mulard L, Canard B, Mechanistic insights into the suppression of drug resistance by human immunodeficiency virus type 1 reverse transcriptase using alpha-boranophosphate nucleoside analogs, J. Biol. Chem. 2005 Feb;280(5):3838-46.
  • 2004
    Mulard LA, Guerreiro C, Total synthesis of a tetra- and two pentasaccharide fragments of the O-specific polysaccharide of Shigella flexneri serotype 2a, Tetrahedron 2004; 60: 2475-88.
  • 2004
    Benarroch D, Egloff MP, Mulard L, Guerreiro C, Romette JL, Canard B, A structural basis for the inhibition of the NS5 dengue virus mRNA 2′-O-methyltransferase domain by ribavirin 5′-triphosphate, J. Biol. Chem. 2004 Aug;279(34):35638-43.
  • 2004
    Wright K, Guerreiro C, Laurent I, Baleux F, Mulard LA, Preparation of synthetic glycoconjugates as potential vaccines against Shigella flexneri serotype 2a disease, Org. Biomol. Chem. 2004 May;2(10):1518-27.
  • 2004
    Bélot F, Wright K, Costachel C, Phalipon A, Mulard LA, Blockwise approach to fragments of the O-specific polysaccharide of Shigella flexneri serotype 2a: convergent Synthesis of a decasaccharide representative of a dimer of the branched repeating unit, J. Org. Chem. 2004 Feb;69(4):1060-74.
  • 2003
    Clément MJ, Imberty A, Phalipon A, Pérez S, Simenel C, Mulard LA, Delepierre M, Conformational studies of the O-specific polysaccharide of Shigella flexneri 5a and of four related synthetic pentasaccharide fragments using NMR and molecular modeling, J. Biol. Chem. 2003 Nov;278(48):47928-36.
  • 2003
    Gallois-Montbrun S, Chen Y, Dutartre H, Sophys M, Morera S, Guerreiro C, Schneider B, Mulard L, Janin J, Veron M, Deville-Bonne D, Canard B, Structural analysis of the activation of ribavirin analogs by NDP kinase: comparison with other ribavirin targets, Mol. Pharmacol. 2003 Mar;63(3):538-46.
  • 2002
    Bélot F, Costachel C, Wright K, Phalipon A, Mulard LA, Synthesis of the methyl glycoside of a branched octasaccharide fragment specific for the Shigella flexneri serotype 2a O-antigen, Tetrahedron Lett. 2002; 43: 8215-8.
  • 2002
    Gallois-Montbrun S, Schneider B, Chen Y, Giacomoni-Fernandes V, Mulard L, Morera S, Janin J, Deville-Bonne D, Veron M, Improving nucleoside diphosphate kinase for antiviral nucleotide analogs activation, J. Biol. Chem. 2002 Oct;277(42):39953-9.
  • 2002
    Mulard LA, Clément MJ, Imberty A, Delepierre M, Convergent synthesis, NMR and conformational analysis of tetra- and pentasaccharide haptens of the Shigella flexneri 5a O-specific polysaccharide, Eur. J. Org. Chem. 2002, 2486-98.
  • 2002
    Mulard LA, Clément MJ, Segat-Dioury F, Delepierre M, Synthesis and NMR study of a linear pentasaccharide fragment of the Shigella flexneri 5a O-specific polysaccharide, Tetrahedron 2002; 58: 2593-604.
  • 2002
    Mulard L, Alonso JM, Fournier JM, Vaccins polysaccharidiques, Annales de l'Institut Pasteur, Editions scientifiques et médicales Elsevier SAS 2002 p. 37-54.
  • 2001
    Nyholm PG, Mulard LA, Miller CE, Lew T, Olin R, Glaudemans CP, Conformation of the O-specific polysaccharide of Shigella dysenteriae type 1: molecular modeling shows a helical structure with efficient exposure of the antigenic determinant alpha-L-Rhap-(1–>2)-alpha-D-Galp, Glycobiology 2001 Nov;11(11):945-55.
  • 2001
    Sekowska A, Mulard L, Krogh S, Tse JK, Danchin A, MtnK, methylthioribose kinase, is a starvation-induced protein in Bacillus subtilis, BMC Microbiol. 2001;1:15.
  • 2001
    Schneider B, Meyer P, Sarfati S, Mulard L, Guerreiro C, Boretto J, Janin J, Véron M, Deville-Bonne D, Canard B, Activation of anti-reverse transcriptase nucleotide analogs by nucleoside diphosphate kinase: improvement by alpha-boranophosphate substitution, Nucleosides Nucleotides Nucleic Acids 2001 Apr-Jul;20(4-7):297-306.
  • 2000
    Selmi B, Boretto J, Navarro JM, Sire J, Longhi S, Guerreiro C, Mulard L, Sarfati S, Canard B, The valine-to-threonine 75 substitution in human immunodeficiency virus type 1 reverse transcriptase and its relation with stavudine resistance, J. Biol. Chem. 2001 Apr;276(17):13965-74.
  • 2000
    Costachel C, Sansonetti PJ, Mulard LA, Linear synthesis of the methyl glycosides of tetra- and pentasaccharide fragments specific for the Shigella flexneri serotype 2a O-antigen, J. Carbohydr. Chem. 2000; 19: 1131-50.
  • 2000
    Mulard LA, Ughetto-Monfrin J, Linear synthesis of the methyl glycosides of tri-, tetra-, and pentasaccharide fragments of the Shigella flexneri serotype 5a O-antigen, J Carbohydr Chem 2000; 19: 503-26.
  • 2000
    Mulard LA, Costachel C, Sansonetti PJ, Synthesis of the methyl glycosides of a di- and two trisaccharide fragments specific for the Shigella flexneri serotype 2a O-antigen, J. Carbohydr. Chem. 2000; 19: 849-77.
  • 2000
    Mulard LA, Ughetto-Monfrin J, First synthesis of a branched pentasaccharide representative of the repeating unit of the Shigella flexneri serotype 5a O-antigen, J Carbohydr Chem 2000; 19: 193-220.
  • 1999
    Villeneuve S, Boutonnier A, Mulard LA, Fournier JM, Immunochemical characterization of an Ogawa-Inaba common antigenic determinant of Vibrio cholerae O1, Microbiology (Reading, Engl.) 1999 Sep;145 ( Pt 9):2477-84.
  • 1999
    Mulard LA, Ughetto-Monfrin J, Synthesis of the methyl glycosides of a tri- and tetrasaccharide fragment specific for the Shigella flexneri serotype 5a O-antigen. A reinvestigation, J Carbohydr Chem 1999; 18: 721-53.
  • 1998
    Mulard LA, Glaudemans CP, Synthesis of tri- and tetrasaccharide fragments of the Shigella dysenteriae type 1 O-antigen deoxygenated and fluorinated at position 3 of the methyl alpha-D-galactopyranoside terminus, Carbohydr. Res. 1998 Sep;311(3):121-33.
  • 1998
    Miller CE, Mulard LA, Padlan EA, Glaudemans CP, Binding of modified fragments of the Shigella dysenteriae type 1 O-specific polysaccharide to monoclonal IgM 3707 E9 and docking of the immunodeterminant to its modeled Fv, Carbohydr. Res. 1998 Jul;309(3):219-26.
  • 1997
    Coxon B, Sari N, Mulard LA, Kovàc P, Pozsgay V, Glaudemans CPJ, Investigation by NMR spectroscopy and molecular modeling of the conformations of some modified disaccharide antigens for Shigella dysenteriae type 1, J Carbohydr Chem 1997; 16: 927-46.
  • 1995
    Mulard LA, Claudemans CP, Synthesis of specifically deoxygenated disaccharide derivatives of the Shigella dysenteriae type 1 O-antigen, Carbohydr. Res. 1995 Sep;274:209-22.
  • 1994
    Mulard LA, Kovác P, Glaudemans CP, Synthesis of specifically monofluorinated ligands related to the O-polysaccharide of Shigella dysenteriae type 1, Carbohydr. Res. 1994 Jun;259(1):21-34.
  • 1994
    Mulard LA, Kovác P, Glaudemans CP, Fluorination at position 6 of derivatives of methyl alpha-D-galactopyranoside, Carbohydr. Res. 1994 Jun;259(1):117-29.
  • 1994
    Mulard LA, Kovác P, Glaudemans CP, Synthesis of methyl O-alpha-L-rhamnopyranosyl-(1–>2)-alpha-D-galactopyranosides specifically deoxygenated at position 3, 4, or 6 of the galactose residue, Carbohydr. Res. 1994 Jan;251:213-32.
  • 1993
    Czernecki S, Mulard L, Valery JM, Commercon A, Synthesis of 2′-deoxy-2′-spirocyclopropyl cytidine as potential inhibitor of Ribonucleoside Diphosphate Reductase, Can J Chem 1993; 71: 413-6.
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