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  • Director of Center
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About

I have been involved in genomic projects for prokaryotic and human genetic studies (GWAS) since 1998.
Currently, I am working on novel visualization techniques to explore large and highly complex data sets. I have develop a web based graphical user interface, called SynTView (http://genopole.pasteur.fr/SynTView/) to visualize biological features in comparative genomic studies. The tool allows interactive visualization of microbial genomes to investigate massive amounts of information efficiently. The software is characterized by the presentation of synthetic organisations of microbial genomes and the visualization of polymorphism data. I am extending this work into designing novel dynamic views for comparative analysis of viruses in emerging disease.

Courses

09:00
10
May 2016
Course

Morning session – Introduction to NGS data analysis

The Hub of Bioinformatics and Biostatistics at the Institut Pasteur organizes thematic courses open to everybody. The second session, entitled “Introduction to NGS data analysis” will take place every Tuesday, from the May 10th […]
Claudia Chica
Frédéric Lemoine
Jack Christophe Cossec
Hugo Varet
Anne Biton
Natalia Pietrosemoli
Guilhem Janbon
Rachel Torchet
Pierre Lechat
Amine Ghozlane
Nicolas Maillet
Axel Cournac
2016-05-10 09:00:00 2016-06-28 12:00:00 Europe/Paris Morning session – Introduction to NGS data analysis The Hub of Bioinformatics and Biostatistics at the Institut Pasteur organizes thematic courses open to everybody. The second session, entitled “Introduction to NGS data analysis” will take place every Tuesday, from the May 10th […] 28 Rue du Dr Roux, Paris, France

Projects

Project
Ongoing
15 Members

Bioconvert

Thomas Cokelaer (PI)

Bioconvert is a collaborative project to facilitate the interconversion of life science data from one format to another. Life science uses many different formats. They may be old, or with complex syntax and converting […]
Project
Ongoing
5 Members

Dynamics of high avidity CD4+ T cell clonotypes directed at HIV-1 capsid

Lisa Chakrabarti (PI)

We obtained recent evidence that CD4+ T cells of HIV Controllers preferentially express a particular set of shared T cell receptors (TCRs) directed to the HIV capsid. We will  monitor the dynamics of these […]
Project
Completed
9 Members

ANR TransLeish – Discovery of druggable protein kinases in the protozoan parasite Leishmania donovani using hit compounds identified by phenotypic screening

Najma Rachidi (PI)

The protozoan parasite Leishmania donovani causes fatal visceral leishmaniasis, one of the most neglected tropical diseases. In the absence of economic incentive, serious Research and Development (R&D) investments into anti-leishmanial drug development lack from […]

Software

Software
Ongoing
6 Members

JASS – Joint Analysis of (GWAS) Summary Statistics

Hugues Aschard (PI)

JASS is a python package that handles the computation of the joint statistics over sets of selected GWAS results, and the interactive exploration of the results through a web interface. The generation of joint […]
Software
Ongoing
4 Members

Listeriomics: an Interactive Web Platform for Systems Biology of Listeria

Christophe Becavin (PI)

Listeriomics integrates all complete genomes, transcriptomes and proteomes published for Listeria species to date. It allows navigating among all these datasets with enriched metadata in a user-friendly format. listeriomics.pasteur.fr The main purpose of the website is […]
Software
Completed
2 Members

SynTView

Pierre Lechat (PI)

SynTView is a comparative and interactive viewer for microbial genomes, designed to run as either a web-based tool (Flash technology) or a desktop application (AIR environment). The basis of the program is a generic […]
Software
Ongoing
8 Members

SHAMAN: SHiny Application for Metagenomic ANalysis

Amine Ghozlane (PI)

SHAMAN is a SHiny Application for Metagenomic ANalysis including the normalization, the differential analysis and mutiple visualization. SHAMAN is based on DESeq2 R package [Anders and Huber 2010] for the analysis of metagenomic data, […]

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