Morning session – Introduction to NGS data analysis
The Hub of Bioinformatics and Biostatistics at the Institut Pasteur organizes thematic courses open to everybody. The second session, entitled “Introduction to NGS data analysis” will take place every Tuesday, from the May 10th […]
CryptoVIEW: Unraveling pathogenesis of Cryptococcosis using optical and multimodal visualizaion of enigmatic events and virulence aspects in vivo.
Cryptococcus neoformans and C. gattii are encapsulated yeasts that can cause life-threatening disease; mainly in immune-suppressed patients, but also in immune-competent individuals. Cryptococcosis affects the lung and may spread to the brain, manifesting itself […]
lncRNAs in Cryptococcus neoformans
During the last decade, advances in the sequencing technologies have revealed a large set of new eukaryotic RNA molecules. For instance, whereas 75% of the human genome was recently reported to be transcribed only […]
Intron dependant gene expression regulation in Cryptococcus neoformans
Most Cryptococccus neoformans genes are interrupted by introns, and alternative splicing occurs very often. In order to gain deeper insights into the distribution of introns in the C. neoformans genome, we have used RNA-Seq […]
2018Cryptococcus neoformans can form titan-like cells in vitro in response to multiple signals, PLoS Pathog. 2018 May;14(5):e1007007.
2018Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators, PLoS Pathog. 2018 05;14(5):e1006982.
2018Introns in Cryptococcus, Mem. Inst. Oswaldo Cruz 2018;113(7):e170519.
2018Glycosylphosphatidylinositol Anchors from Galactomannan and GPI-Anchored Protein Are Synthesized by Distinct Pathways in Aspergillus fumigatus, J Fungi (Basel) 2018 Feb;4(1).
2017Environmental Triazole Induces Cross-Resistance to Clinical Drugs and Affects Morphophysiology and Virulence of Cryptococcus gattii and C. neoformans, Antimicrob. Agents Chemother. 2018 Jan;62(1).
2017Introns Protect Eukaryotic Genomes from Transcription-Associated Genetic Instability, Mol. Cell 2017 Aug;67(4):608-621.e6.
2016Intron retention-dependent gene regulation in Cryptococcus neoformans, Sci Rep 2016 Aug;6:32252.
2015Biofilm formation in Candida glabrata: What have we learnt from functional genomics approaches?, FEMS Yeast Res. 2016 Feb;16(1):fov111.
2015Role of Cln1 during melanization of Cryptococcus neoformans, Front Microbiol 2015;6:798.
2015Systematic functional profiling of transcription factor networks in Cryptococcus neoformans, Nat Commun 2015;6:6757.
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