Morning session – Introduction to NGS data analysis
The Hub of Bioinformatics and Biostatistics at the Institut Pasteur organizes thematic courses open to everybody. The second session, entitled “Introduction to NGS data analysis” will take place every Tuesday, from the May 10th […]
CryptoVIEW: Unraveling pathogenesis of Cryptococcosis using optical and multimodal visualizaion of enigmatic events and virulence aspects in vivo.
Cryptococcus neoformans and C. gattii are encapsulated yeasts that can cause life-threatening disease; mainly in immune-suppressed patients, but also in immune-competent individuals. Cryptococcosis affects the lung and may spread to the brain, manifesting itself […]
lncRNAs in Cryptococcus neoformans
During the last decade, advances in the sequencing technologies have revealed a large set of new eukaryotic RNA molecules. For instance, whereas 75% of the human genome was recently reported to be transcribed only […]
Intron dependant gene expression regulation in Cryptococcus neoformans
Most Cryptococccus neoformans genes are interrupted by introns, and alternative splicing occurs very often. In order to gain deeper insights into the distribution of introns in the C. neoformans genome, we have used RNA-Seq […]
2021Cryptococcus extracellular vesicles properties and their use as vaccine platforms., J Extracell Vesicles 2021 08; 10(10): e12129.
2021Structure, composition and biological properties of fungal extracellular vesicles, microLife, Volume 2, 2021, uqab009.
2021Commensalism instead of sex? Adapting mating to live in the gut., Cell Host Microbe 2021 06; 29(6): 856-858.
2021Population genomic analysis of Cryptococcus Brazilian isolates reveals an African type subclade distribution., G3 (Bethesda) 2021 Apr; (): .
2021Application of an optimized annotation pipeline to the Cryptococcus deuterogattii genome reveals dynamic primary metabolic gene clusters and genomic impact of RNAi loss., G3 (Bethesda) 2021 Feb; 11(2): .
2020Extracellular Vesicles in Fungi: Past, Present, and Future Perspectives., Front Cell Infect Microbiol 2020 ; 10(): 346.
2020The Added Value of Longitudinal Imaging for Preclinical In Vivo Efficacy Testing of Therapeutic Compounds against Cerebral Cryptococcosis., Antimicrob. Agents Chemother. 2020 06; 64(7): .
2020Quantitative global studies reveal differential translational control by start codon context across the fungal kingdom., Nucleic Acids Res 2020 03; 48(5): 2312-2331.
2020Mating-Type-Specific Ribosomal Proteins Control Aspects of Sexual Reproduction in Cryptococcus neoformans., Genetics 2020 03; 214(3): 635-649.
2019Sensitive bioluminescence imaging of fungal dissemination to the brain in mouse models of cryptococcosis., Dis Model Mech 2019 06; 12(6): .
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