Biomics protocoles’ project
This project aims to provide users of Biomics core facility with simplified protocols. The protocols are available in English and French. They include all the steps needed for sequencing: quantification, quality control, fragmentation, library […]
Oncobiomics – THE (heterogenity tumor ecosystem)
The Oncobiomics project is conducted in the HTE (heterogenity tumor ecosystem) national program launched by the cancer nation institute (Inca) in the third national cancer plan 2014-2019. It’s a consortium project involving 8 teams […]
Outsourcing high throughput sequencing projects
NovaSeq 6000 High throughput NGS sequencing is now available at Biomics core facility. This is using the same types of libraries as other Illumina sequencers. Sequencing (only PE150, ≥ 400M reads) is outsourced to […]
ATPase inhibitors, the cases of human heat shock protein 90 and bacterial type IIA topoisomerases
Organic synthesis, still the limiting factor of Medicinal Chemistry? This ongoing project is based on our reviews (1-3) on the inhibitors of the ATPase functions of human heat shock protein 90 (HSP90) or bacterial […]
2016Synthesis and evaluation of original bioisosteres of bacterial type IIA topoisomerases inhibitors, Can. J. Chem. 2016, 94 , 240-250.
2015Multilocus sequence analysis of the genus Citrobacter and description of Citrobacter pasteurii sp. nov, Int. J. Syst. Evol. Microbiol. 2015 May;65(Pt 5):1486-90.