Implementation of an NGS core facility at Institut Pasteur of Tunis: Biomics as capacity building model
Between 2018 and 2022, and as Biomics project manager, I contributed to a large capacity building in Pathogen-Host Interaction Data access project (PHINDaccess) which is coordinated by the Institut Pasteur de Tunis (IPT) and […]
Supervision of the quality management system ISO 9001
Supervision of the quality management system (QMS) based on International Standards of Organization ISO9001 requirements is one of Biomics’ missions. The platform has been certified since 2017. An external audit system allows us to […]
Biomics protocoles’ project
This project aims to provide users of Biomics core facility with simplified protocols. The protocols are available in English and French. They include all the steps needed for sequencing: quantification, quality control, fragmentation, library […]
Oncobiomics – THE (heterogenity tumor ecosystem)
The Oncobiomics project is conducted in the HTE (heterogenity tumor ecosystem) national program launched by the cancer nation institute (Inca) in the third national cancer plan 2014-2019. It’s a consortium project involving 8 teams […]
Outsourcing high throughput sequencing projects
NovaSeq 6000 High throughput NGS sequencing is now available at Biomics core facility. This is using the same types of libraries as other Illumina sequencers. Sequencing (only PE150, ≥ 400M reads) is outsourced to […]
ATPase inhibitors, the cases of human heat shock protein 90 and bacterial type IIA topoisomerases
Organic synthesis, still the limiting factor of Medicinal Chemistry? This ongoing project is based on our reviews (1-3) on the inhibitors of the ATPase functions of human heat shock protein 90 (HSP90) or bacterial […]
Single Cell Transcriptomics
The single cell transcriptomics, epigenetic and genomics are supported by collaborative effort of the CB UTechS and Biomics. The CB UTechS gathers expertise and high-end instrumentation for single cell phenotyping and sorting, single cell […]
2021How Did Institut Pasteur’s NGS Core Facility, Biomics, Manage the Coronavirus Disease 2019 Crisis?, J Biomol Tech 2021 07; 32(2): 50-56.
2020SHAMAN: a user-friendly website for metataxonomic analysis from raw reads to statistical analysis., BMC Bioinformatics 2020 Aug; 21(1): 345.
2016Synthesis and evaluation of original bioisosteres of bacterial type IIA topoisomerases inhibitors, Can. J. Chem. 2016, 94 , 240-250.
2015Multilocus sequence analysis of the genus Citrobacter and description of Citrobacter pasteurii sp. nov., Int J Syst Evol Microbiol 2015 May; 65(Pt 5): 1486-1490.
2013Lactobacillus pasteurii sp. nov. and Lactobacillus hominis sp. nov., Int J Syst Evol Microbiol 2013 Jan; 63(Pt 1): 53-59.
2012Lactobacillus gigeriorum sp. nov., isolated from chicken crop., Int J Syst Evol Microbiol 2012 Feb; 62(Pt 2): 330-334.
2009Pseudomonas brassicacearum subsp. neoaurantiaca subsp. nov., orange-pigmented bacteria isolated from soil and the rhizosphere of agricultural plants., Int J Syst Evol Microbiol 2009 Oct; 59(Pt 10): 2476-81.
2001Airway administration of Escherichia coli endotoxin to mice induces glucocorticosteroid-resistant bronchoconstriction and vasopermeation., Am J Respir Cell Mol Biol 2001 Mar; 24(3): 345-51.