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Morning session – Introduction to NGS data analysis
The Hub of Bioinformatics and Biostatistics at the Institut Pasteur organizes thematic courses open to everybody. The second session, entitled “Introduction to NGS data analysis” will take place every Tuesday, from the May 10th […]
2016-05-10 09:00:00 2016-06-28 12:00:00 Europe/Paris Morning session – Introduction to NGS data analysis The Hub of Bioinformatics and Biostatistics at the Institut Pasteur organizes thematic courses open to everybody. The second session, entitled “Introduction to NGS data analysis” will take place every Tuesday, from the May 10th […] 28 Rue du Dr Roux, Paris, France
Thomas Cokelaer (PI)
Bioconvert is a collaborative project to facilitate the interconversion of life science data from one format to another. Life science uses many different formats. They may be old, or with complex syntax and converting […]
Dynamics of high avidity CD4+ T cell clonotypes directed at HIV-1 capsid
Lisa Chakrabarti (PI)
We obtained recent evidence that CD4+ T cells of HIV Controllers preferentially express a particular set of shared T cell receptors (TCRs) directed to the HIV capsid. We will monitor the dynamics of these […]
ANR TransLeish – Discovery of druggable protein kinases in the protozoan parasite Leishmania donovani using hit compounds identified by phenotypic screening
Najma Rachidi (PI)
The protozoan parasite Leishmania donovani causes fatal visceral leishmaniasis, one of the most neglected tropical diseases. In the absence of economic incentive, serious Research and Development (R&D) investments into anti-leishmanial drug development lack from […]
JASS – Joint Analysis of (GWAS) Summary Statistics
Hugues Aschard (PI)
JASS is a python package that handles the computation of the joint statistics over sets of selected GWAS results, and the interactive exploration of the results through a web interface. The generation of joint […]
Listeriomics: an Interactive Web Platform for Systems Biology of Listeria
Christophe Becavin (PI)
Listeriomics integrates all complete genomes, transcriptomes and proteomes published for Listeria species to date. It allows navigating among all these datasets with enriched metadata in a user-friendly format. listeriomics.pasteur.fr The main purpose of the website is […]
Pierre Lechat (PI)
SynTView is a comparative and interactive viewer for microbial genomes, designed to run as either a web-based tool (Flash technology) or a desktop application (AIR environment). The basis of the program is a generic […]
SHAMAN: SHiny Application for Metagenomic ANalysis
Amine Ghozlane (PI)
SHAMAN is a SHiny Application for Metagenomic ANalysis including the normalization, the differential analysis and mutiple visualization. SHAMAN is based on DESeq2 R package [Anders and Huber 2010] for the analysis of metagenomic data, […]
Education & internship
2018Genome Dynamics during Environmental Adaptation Reveal Strain-Specific Differences in Gene Copy Number Variation, Karyotype Instability, and Telomeric Amplification, mBio 2018 11;9(6).
2018Characterization of LE3 and LE4, the only lytic phages known to infect the spirochete Leptospira, Sci Rep 2018 Aug;8(1):11781.
2017LipL21 lipoprotein binding to peptidoglycan enables Leptospira interrogans to escape NOD1 and NOD2 recognition, PLoS Pathog. 2017 12;13(12):e1006725.
2017Listeriomics: an Interactive Web Platform for Systems Biology of Listeria, mSystems 2017 Mar-Apr;2(2).
2016Multiple major disease-associated clones of Legionella pneumophila have emerged recently and independently, Genome Res. 2016 Sep;.
2016Species- and Strain-Specific Adaptation of the HSP70 Super Family in Pathogenic Trypanosomatids, Genome Biol Evol 2016 07;8(6):1980-95.
2016Public T cell receptors confer high-avidity CD4 responses to HIV controllers, J. Clin. Invest. 2016 Apr;.
2014Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline, Nat Commun 2014 Aug;5:4544.
2014Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline., Nat Commun. 2014 Aug 4;5:4544 Erratum in : Nat Commun. 2015; 6:6108.
2014Comparison of widely used Listeria monocytogenes strains EGD, 10403S, and EGD-e highlights genomic variations underlying differences in pathogenicity, MBio 2014;5(2):e00969-14.
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