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Understanding viral attenuation for the rationalization of vaccine design
Nolwenn Jouvenet (PI)
Vaccination is one of the greatest successes of modern medicine. The first generation of viral vaccines relied on empiric attenuation by repeated passage in animals and/or cultured cells. A successful attenuation process eliminates virulence […]
2018RIG-I Recognizes the 5′ Region of Dengue and Zika Virus Genomes., Cell Rep. 2018 Jul 10;24(2):320-328.
2016Vaccine and Wild-Type Strains of Yellow Fever Virus Engage Distinct Entry Mechanisms and Differentially Stimulate Antiviral Immune Responses, MBio. 2016 Feb 9;7(1). pii: e01956-15. doi: 10.1128/mBio.01956-15..