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  • PhD Student
  • Physician
  • Post-doc
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  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
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© Gail Rozen-Gagnon, Christine Schmitt,
Cells infected with Chikungunya (CHIK) virus.

Transversal Projects

Defeat Dengue

300 to 400 million cases of dengue fever occur each year worldwide. Spreading rapidly, more than 40% of the world’s population is now at risk of contracting dengue This transversal program brings together talents […]

LabEx IBEID – Integrative Biology of Emerging Infectious Diseases

Presentation The aim of the Integrative Biology of Emerging Infectious Diseases (IBEID) project, coordinated by Professors Philippe Sansonetti and Pascale Cossart, is to develop a structure to anticipate and tackle emerging infectious diseases (EIDs). […]

Projects

project
Ongoing
13 Members

Emergency response to global threats of emerging and re-emerging pathogens

Maria Van Kerkhove (PI)

With over 125 years’ experience with infectious diseases, the Institut Pasteur and the Institut Pasteur International Network (IPIN), which is composed of 33 research institutes in 26 countries and five continents, are ideally positioned […]
project
Ongoing
3 Members

ERC-2013-ADG CELCELFUS

Félix A. Rey (PI)

Cell-Cell fusion in fertilization and developmental biology: a structural biology approach. My group has made seminal contributions in the past toward understanding the mechanism of membrane fusion used by enveloped viruses to infect a […]
project
Ongoing
7 Members

DENFREE consortium – Dengue Framework for Resisting Epidemics in Europe

Anavaj Sakuntabhai (PI)

The main objective of the programme is to focus on finding key factors determining dengue transmission and dynamics in order to develop new tools and strategies for controlling dengue transmission. We will estimate the […]
project
Ongoing
2 Members

Protein Data Bank depositions

Félix A. Rey (PI)

PDB Crystal Structures Resolution (A) Year NON-VIRAL proteins Eukariotyc cell-cell fusion 4OJC Wild-type full-length trimeric ectodomain of C. elegans fusion protein EFF-1  2.93 2014 4OJD C-ter truncated trimeric ectodomain of C. elegans fusion protein […]
project
Ongoing
2 Members

Rubella virus E1 envelope glycoprotein

Rubella virus E1 envelope glycoprotein (PI)

  Little is known about the three-dimensional organization of rubella virus, which causes a relatively mild measles-like disease in children but leads to serious congenital health problems when contracted in utero. Although rubella virus […]
project
Ongoing
3 Members

Respiratory Syncytial virus

Félix A. Rey (PI)

  Respiratory Syncytial Virus Nucleoprotein-RNA complex     Human respiratory syncytial virus (RSV) is the most important viral agent of pediatric respiratory tract disease worldwide, causing pneumonia and bronchiolitis in infants. No vaccine is currently […]
project
Ongoing
2 Members

Picobirnavirus capsid protein

Picobirnavirus capsid protein (PI)

  Double-stranded (ds) RNA virus particles are organized around a central icosahedral core capsid made of 120 identical subunits. This core capsid is unable to invade cells from outside, and animal dsRNA viruses have […]
project
Ongoing
4 Members

Pestivirus

Félix A. Rey (PI)

 Bovine Viral Diarrhea virus envelop protein E(rns) Pestiviruses, which belong to the Flaviviridae family of RNA viruses, are important agents of veterinary diseases causing substantial economical losses in animal farming worldwide. Pestivirus particles display […]
project
Ongoing
2 Members

Herpesvirus

Herpesvirus (PI)

  Herpesviruses envelop glycoproteins     Herpesviridae are a large family of double-stranded DNA viruses, counting more than 200 members that infect humans and a wide range of invertebrates and vertebrates. Herpesviruses carry a […]
project
Ongoing
2 Members

Hepatitis C virus

Hepatitis C virus (PI)

  Hepatitis C virus E2 envelop glycoprotein     The hepatitis C virus (HCV) is a major cause of chronic liver disease worldwide, leading to cirrhosis and hepatocellular carcinoma. In spite of being the focus […]
project
Ongoing
2 Members

Dengue virus

Dengue virus (PI)

  Dengue virus E envelop glycoprotein The dengue virus (DENV) is a mosquito-borne member of the flavivirus genus responsible for roughly 50 million human infections each year. DENV is composed of four distinct but […]
project
Ongoing
3 Members

Chikungunya virus

Félix A. Rey (PI)

Chikungunya virus p62-E1 envelope glycoproteins The Chikungunya virus (CHIKV) is an emerging mosquito-borne alphavirus that has caused widespread outbreaks of a debilitating human disease in the last 5 years. CHIKV invasion of susceptible cells […]
project
Ongoing
2 Members

C. elegans Eff-1

C. elegans Eff-1 (PI)

  Cell-cell fusion proteins are essential in development. We show that the C. elegans cell-cell fusion protein EFF-1 is structurally homologous to viral class II fusion proteins. The 2.6 Ang. crystal structure of the […]
project
Completed
2 Members

Arenavirus

Félix A. Rey (PI)

Lymphocytic choriomeningitis virus GP2 envelop protein Arenaviruses are important agents of zoonotic disease worldwide. The virions expose a tripartite envelope glycoprotein complex (GPC) at their surface, formed by the glycoprotein subunits GP1, GP2 and […]
project
Ongoing
6 Members

Chikungunya virus pathogenesis

Marc Lecuit (PI)

Structural and functional studies of Chikungunya virus entry into host cells Deciphering Chikungunya virus cell biology by high-throughput / high-content screening Chikungunya virus infection of fibroblasts Chikungunya virus and the central nervous system infection  

Publications

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