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  • Director of Center
  • Director of Department
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© Gail Rozen-Gagnon, Christine Schmitt,
Cells infected with Chikungunya (CHIK) virus.
Scientific Fields
Diseases
Organisms
Applications
Technique

About

Flavivirus NS1 is involved in the intracellular stages of virus replication. It also circulates in the extracellular medium although its related function remains unknown. We have developed a dengue diagnostic kit based on the NS1 antigen capture by ELISA that has become a reference in the field since its commercialization by BioRad in 2006. We are currently pursuing the functional characterization of the secreted form of dengue virus NS1 in an attempt to specify its contribution to fatal hemorrhagic fevers.

Projects

project
Ongoing
8 Members

Pathogenicity and resistance to Rift Valley Fever virus.

Jean-Jacques Panthier (PI)

Rift Valley fever is a serious emerging viral disease that primarily affects domesticated animals (such as cattle, sheep and goats) and humans. Recurrent outbreaks have been documented in sub-Saharan Africa and have spread outside […]
project
Ongoing
2 Members

Viral toxins

Marie Flamand (PI)

Biological study of secreted dengue virus nonstructural protein NS1 Flavivirus NS1 is involved in the intracellular stages of virus replication. It also circulates in the extracellular medium although its related function remains unknown. We […]

Publications

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