Timeline

Félix A. Rey
Head of Structure
02 Nov 2023
publication

SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells.

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25 Oct 2023
publication

TMPRSS2 is a functional receptor for human coronavirus HKU1.

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18 Sep 2023
project

FURTHEST: Unraveling the Foamy Virus interactions with the host: insights into the molecular mechanisms of entry and neutralization

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21 Aug 2023
publication

New insight into flavivirus maturation from structure/function studies of the yellow fever virus envelope protein complex

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10 Jul 2023
publication

Qualitative monitoring of SARS-CoV-2 mRNA vaccination in humans using droplet microfluidics.

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14 Jun 2023
publication

Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody.

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05 Apr 2023
publication

SARS‐CoV‐2‐related bat virus behavior in human‐relevant models sheds light on the origin of COVID‐19

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01 Apr 2023
publication

Neutralization of zoonotic retroviruses by human antibodies: Genotype-specific epitopes within the receptor-binding domain from simian foamy virus.

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28 Mar 2023
publication

Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein.

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06 Mar 2023
publication

The crystal structure of a simian Foamy Virus receptor binding domain provides clues about entry into host cells.

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15 Sep 2022
event

“Structural biology of beneficial viruses: the anatomy of a flagellotropic bacteriophage and surprises in the architecture of flaviviruses.”

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04 Jul 2022
publication

Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.

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28 Jun 2022
publication

Evolution and activation mechanism of the flavivirus class II membrane-fusion machinery.

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17 Jun 2022
news

New publication – Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2

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24 May 2022
publication

Dengue virus NS1 protein conveys pro-inflammatory signals by docking onto high-density lipoproteins.

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14 Apr 2022
publication

Bat coronaviruses related to SARS-CoV-2 and infectious for human cells.

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08 Apr 2022
news

New publication – Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller

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12 Mar 2022
publication

Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2.

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07 Mar 2022
publication

Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller.

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01 Feb 2022
publication

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization.

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07 Jan 2022
publication

Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.

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09 Dec 2021
publication

The epitope arrangement on flavivirus particles contributes to Mab C10’s extraordinary neutralization breadth across Zika and dengue viruses.

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15 Sep 2021
project

Foamy virus Env protein – where virus meets the cells and host immune system

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01 Sep 2021
publication

Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling.

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08 Jul 2021
publication

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization.

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11 Jun 2021
news

COVID-19: sensitivity of the Indian variant (B.1.617.2) to monoclonal antibodies and sera from convalescent and vaccinated individuals

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09 Jan 2021
project

PTR2020-353 ZOOFOAMENV – Host pathogens interactions in humans infected with zoonotic foamy viruses

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15 Oct 2020
publication

The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.

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02 Sep 2020
publication

A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations

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05 Jun 2020
publication

A nicotinic hypothesis for Covid-19 with preventive and therapeutic implications.

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10 Apr 2020
project

CORONABODIES

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07 Feb 2020
news

RABIES : New perspectives for prevention and treatment

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31 Jan 2020
news

Coronavirus : Mobilisation Equipes de l’Institut Pasteur

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30 Jan 2020
publication

Structure of the prefusion-locking broadly neutralizing antibody RVC20 bound to the rabies virus glycoprotein.

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06 Dec 2019
publication

X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications.

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08 Feb 2019
team

UMR3569 – Virology

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01 Feb 2019
event

Virology Department : PhD Thesis Defense “Structural and functional studies on human syncytins -Insights into the molecular mechanisms of placental cell-cell fusion” with Catharina Ruigrok

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23 Feb 2017
publication

The Ancient Gamete Fusogen HAP2 Is a Eukaryotic Class II Fusion Protein.

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13 Jan 2017
event

SEMINAR OF THE VIROLOGY DEPARTMENT

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06 Jan 2017
event

Conférence du Conseil Scientifique : Flavivirus structural heterogeneity: implications for entry, antibody neutralisation and vaccine design

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27 Oct 2015
project

ERC-2013-ADG CELCELFUS

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11 Sep 2015
project

DENFREE consortium – Dengue Framework for Resisting Epidemics in Europe

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03 Aug 2015
project

Protein Data Bank depositions

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04 Jul 2015
project

Rubella virus E1 envelope glycoprotein

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04 Jul 2015
project

Respiratory Syncytial virus

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04 Jul 2015
project

Picobirnavirus capsid protein

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04 Jul 2015
project

Pestivirus

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04 Jul 2015
project

Herpesvirus glycoproteins – entry and beyond

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04 Jul 2015
project

Hepatitis C virus

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04 Jul 2015
project

Dengue virus

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04 Jul 2015
project

Chikungunya virus

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04 Jul 2015
project

C. elegans Eff-1

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04 Jul 2015
project

Arenavirus

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11 May 2015
team

Structural Virology

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23 Apr 2015
publication

A replication defect of pseudorabies virus induced by targeted α-helix distortion in the syntaxin-like bundle of glycoprotein H (V275P) is corrected by an adjacent compensatory mutation (V271A).

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04 Feb 2015
publication

X-ray structure of the pestivirus NS3 helicase and its conformation in solution

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15 Dec 2014
publication

A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus

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04 Dec 2014
publication

Rubella virus: first calcium-requiring viral fusion protein

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03 Dec 2014
publication

Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein E2 recognized by broadly neutralizing antibodies

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12 Nov 2014
publication

Structure-based functional analyses of domains II and III of pseudorabies virus glycoprotein H.

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01 Oct 2014
publication

Robust and low cost uniform (15)N-labeling of proteins expressed in Drosophila S2 cells and Spodoptera frugiperda Sf9 cells for NMR applications.

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03 Sep 2014
publication

The highly conserved proline at position 438 in pseudorabies virus gH is important for regulation of membrane fusion.

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10 Apr 2014
publication

Structural basis of eukaryotic cell-cell fusion

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18 Oct 2013
publication

Gain-of-function research: unknown risks

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23 May 2013
publication

Dengue virus: two hosts, two structures

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16 May 2013
publication

Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape

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23 Apr 2013
publication

Alphavirus structure: activation for entry at the target cell surface

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06 Jan 2013
publication

Functional and evolutionary insight from the crystal structure of rubella virus protein E1

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21 Dec 2012
publication

SnapShot: Viral and eukaryotic protein fusogens

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11 Sep 2012
project

Chikungunya virus pathogenesis

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01 May 2012
publication

Crystal structure of the pestivirus envelope glycoprotein E(rns) and mechanistic analysis of its ribonuclease activity

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26 Jan 2012
publication

Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody

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02 Jan 2012
publication

Virus entry: old viruses, new receptors.

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12 Dec 2011
publication

High-level secretion of recombinant monomeric murine and human single-chain Fv antibodies from Drosophila S2 cells

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02 Dec 2011
publication

Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus

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28 Nov 2011
publication

X-ray structure of the arenavirus glycoprotein GP2 in its postfusion hairpin conformation

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12 Oct 2011
publication

Peptides targeting the PDZ domain of PTPN4 are efficient inducers of glioblastoma cell death

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11 Aug 2011
publication

Class II enveloped viruses

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13 Dec 2010
publication

Structure of a core fragment of glycoprotein H from pseudorabies virus in complex with antibody.

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08 Dec 2010
publication

Identification of new functional regions in hepatitis C virus envelope glycoprotein E2

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01 Dec 2010
publication

Glycoprotein organization of Chikungunya virus particles revealed by X-ray crystallography

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19 Feb 2010
publication

The disulfide bonds in glycoprotein E2 of hepatitis C virus reveal the tertiary organization of the molecule

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24 Jan 2010
publication

Efficient method for production of high yields of Fab fragments in Drosophila S2 cells.

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27 Nov 2009
publication

Crystal structure of a nucleocapsid-like nucleoprotein-RNA complex of respiratory syncytial virus

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24 Jun 2009
publication

Single-particle cryoEM reconstructions: meeting the challenge

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30 Apr 2009
publication

The picobirnavirus crystal structure provides functional insights into virion assembly and cell entry

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01 Jun 2007
publication

Characterization of reemerging chikungunya virus

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01 Oct 2006
publication

Molecular gymnastics at the herpesvirus surface

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23 May 2006
publication

Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak

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26 Apr 2005
publication

Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals

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