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© François Gardy, Institut Pasteur
Edition 2023 du Salon du laboratoire de l?Institut Pasteur.
Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
03
Aug 2015
Status
Ongoing
Members
1
Structures
1

About

PDB Crystal Structures Resolution (A) Year

NON-VIRAL proteins

Eukariotyc cell-cell fusion
4OJC Wild-type full-length trimeric ectodomain of C. elegans fusion protein EFF-1  2.93 2014
4OJD C-ter truncated trimeric ectodomain of C. elegans fusion protein EFF-1 G260A/D321E/D322E mutant  2.26 2014
4OJE C-ter truncated trimeric ectodomain of C. elegans fusion protein EFF-1  2.57  2014

VIRAL proteins

Flaviviridae family

Pestiviruses
Bovine viral diarrhea virus
4DVK Glycoprotein Erns from pestivirus BVDV-1 strain NCP-7 2.20 2012
4DVL Glycoprotein Erns from pestivirus BVDV-1 in complex with 2′-3′-cyclo-UMP 2.75 2012
4DVN Glycoprotein Erns from pestivirus BVDV-1 in complex with 2′-UMP 2.38 2012
4DW3 Glycoprotein Erns from pestivirus BVDV-1 in complex with 5′-CMP 2.35 2012
4DW4 Glycoprotein Erns from pestivirus BVDV-1 in complex with 5′-UMP 2.23 2012
4DW5 Glycoprotein Erns from pestivirus BVDV-1 in complex with a non-cleavable CpU dinucleotide 2.21 2012
4DW7 Active-site mutant (H32K) Erns from pestivirus BVDV-1 in complex with a CpU dinucleotide 3.07 2012
4DWA Active-site mutant (H32K) Erns from pestivirus BVDV-1 in complex with a CpUpC trinucleotide 3.01 2012
4DWC Glycoprotein Erns from the pestivirus BVDV-1 in complex with Zn ions 2.89 2012
Flaviviruses
Dengue virus
3UZV Domain III of the envelope protein E from DENV 2 with the variable domains of Mab 4E11 2.10 2012
3UZQ Domain III of the envelope protein E from DENV 1 with the variable domains of Mab 4E11 1.60 2012
3UZE Domain III of the envelope protein E from DENV 3 with the variable domains of Mab 4E11 2.04 2012
3UYP Domain III of the envelope protein E from DENV 4 with the variable domains of Mab 4E11 2.00 2012
3UC0 Domain I of the envelope protein E from DENV 4 with Fab of the chimpanzee monoclonal Ab 5H2 2.71 2011
3UAJ Envelope glycoprotein ectodomain E from DENV 4 with Fab of the chimpanzee monoclonal Ab 5H2 3.23 2011
Tick-Borne Encephalitis Virus
1URZ Post-fusion form of the envelope glycoprotein E from Tick-Borne Encephalitis virus 2.70 2004
1SVB Pre-fusion form of the envelope glycoprotein E from Tick-Borne Encephalitis virus 1.90 1996
Hepaciviruses
Hepatitis C Virus
4JZN Broadly neutralizing human anti-Hepatitis C virus glycoprotein E2 Fab fragment HC84-1 2.05 2013
4JZO Broadly neutralizing human anti-Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC84-27 2.22 2013
4JVP Broadly neutralizing anti-Hepatitis C virus (HCV) glycoprotein E2 alpaca nanobody D03 1.76 2013
3U6R Broadly neutralizing anti-Hepatitis C virus (HCV) glycoprotein E2 single chain FV fragment 1:7 2.67 2011
1GX5 Hepatitis C virus RNA polymerase in complex with ribonucleotides 1.70 2002
1CSJ RNA-dependent RNA polymerase of Hepatitis C virus 2.80 1999

Togaviridade family

Alphaviruses
Chikungunya virus
3N40 Immature envelope glycoproteins p62-E1 of Chikungunya virus 2.17 2010
3N41 Mature envelope glycoproteins complex (spontaneous cleavage) of Chikungunya virus 3.01 2010
3N42 Mature envelope glycoproteins complex (furin cleavage) of Chikungunya virus 3.00 2010
3N43 Mature envelope glycoproteins complex (trypsin cleavage) of Chikungunya virus 2.58 2010
3N44 Mature envelope glycoproteins complex (trypsin cleavage; osmium soak) of Chikungunya virus 2.35 2010
2XFB Fit of the Chikungunya E2-E1 envelope glycoproteins into Sindbis virus cryo-EM map 9.00 2010
2XFC Fit of the Chikungunya E2-E1 envelope glycoproteins into Semliki Forest virus cryo-EM map 9.00 2010
Semliki Forest virus
2V33 Domain III of E1 fusion glycoprotein from Semliki Forest virus 1.55 2008
2ALA Semliki Forest virus envelope protein E1 in its monomeric conformation 3.00 2006
1I9W Pre-fusion form of the envelope glycoprotein E1 from Semliki Forest virus 3.00 2004
1RER Post-fusion form of the envelope glycoprotein E1 from Semliki Forest virus 3.20 2004
Rubiviridae
Rubella virus
4ADI Post-fusion form of the envelope fusion protein E1 from Rubella virus (Na+) 1.78 2013
4ADG Post-fusion form of the envelope fusion protein E1 from Rubella virus (Ca+, soak Gal3S)  2.18 2013
4ADJ Post-fusion form of the envelope fusion protein E1 from Rubella virus (Ca+ 1mM)  1.94 2013
4B3V Post-fusion form of the envelope fusion protein E1 from Rubella virus (Ca+, 20mM)  1.98 2013

Retroviridae family

Human immunodeficiency virus (HIV-1)
2XT1 HIV-1 capsid protein C-terminal domain (146-231) in complex with a camelid VHH 1.32 2011
2XV6 HIV-1 capsid protein C-terminal domain (146-220) in complex with a camelid VHH 1.90 2011
2XXC Camelid VHH raised against the HIV-1 capsid protein C-terminal domain 1.67 2011
2XXM HIV-1 capsid C-terminal domain in complex with a Camelid VHH and the CAI peptide 1.65 2011
3DPH HIV-1 capsid C-terminal domain mutant (L211S) 2.01 2008
3DS0 HIV-1 capsid C-terminal domain mutant (N183A) in complex with an inhibitor of particle assembly 1.60 2008
3DS1 HIV-1 capsid C-terminal domain mutant (E187A) in complex with an inhibitor of particle assembly 1.60 2008
3DS2 HIV-1 capsid C-terminal domain mutant (Y169A) 1.20 2008
3DS3 HIV-1 capsid C-terminal domain mutant (Y169A) in complex with an inhibitor of particle assembly 2.70 2008
3DS4 HIV-1 capsid C-terminal domain mutant (L211S) in complex with an Inhibitor of particle assembly 1.12 2008
3DS5 HIV-1 capsid C-terminal domain mutant (N183A) 2.40 2008
3DTJ HIV-1 capsid C-terminal domain mutant (E187A) 4.00 2008
2BUO HIV-1 capsid C-terminal domain in complex with an inhibitor of particle assembly 1.70 2005
Endogenous retrovirus
1Y4M Human endogenous retrovirus HERV-FRD envelope protein (syncitin-2) 1.60 2005

Arenaviridae family (arenavirus)

Lymphocytic Choriomeningitis virus
3MKO Lymphocytic Choriomeningitis virus membrane fusion glycoprotein GP2 in post-fusion form 1.80 2011
Herpesviridae family
Pseudorabies virus
2XQY Pseudorabies core fragment of glycoprotein H in complex with Fab D6.3 2.05 2010

Paramyxoviridae family

Respiratory Syncitial Virus
2WJ8 Respiratory Syncitial virus nucleocapsid-RNA decameric rings 3.29 2009

Rhabdoviridae family

Vesicular Stomatitis Virus
2J6J Pre-fusion form of the Vesicular Stomatitis virus glycoprotein G ectodomain 3.00 2007
2CMZ VSV-Indiana glycoprotein in its acidic conformation 2.40 2006
Coronaviridae family
Coronavirus
1WYY Post-fusion hairpin conformation of the SARS Coronavirus spike glycoprotein 2.20 2005
Other viruses

Dicistroviridae family

3NAP Triatoma virus (TrV) 2.50 2010

Picornaviridae family

2VF1 Capsid of the Picobirnavirus 3.40 2005

Birnaviridae family

3IDE Aquabirnavirus (IPNV) subviral particle 3.35 2009
1WCD Birnavirus IBDV T1 virus-like particle 3.00 2005
1WCE Birnavirus IBDV T13 viral particle 7.00 2005

Reoviridae family

1QHD Major capsid protein VP6 of group A rotavirus 1.95 2001

Non-viral structures

4ACQ Alpha-2 macroglobulin 4.20 2012
2J6E Autoimmune complex between a human IGM rheumatoid factor and IGG1 Fc 3.00 2007