Ligne de temps
Félix Rey
Responsable de Structure
11 oct. 2024
publication
Structures of the Foamy virus fusion protein reveal an unexpected link with the F protein of paramyxo- and pneumoviruses.
Lire plus19 juil. 2024
publication
Broad sarbecovirus neutralization by combined memory B cell antibodies to ancestral SARS-CoV-2.
Lire plus21 juin 2024
publication
Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus.
Lire plus02 nov. 2023
publication
SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells.
Lire plus25 oct. 2023
18 sept. 2023
project
FURTHEST: Unraveling the Foamy Virus interactions with the host: insights into the molecular mechanisms of entry and neutralization
Lire plus21 août 2023
publication
New insight into flavivirus maturation from structure/function studies of the yellow fever virus envelope protein complex
Lire plus10 juil. 2023
publication
Qualitative monitoring of SARS-CoV-2 mRNA vaccination in humans using droplet microfluidics.
Lire plus14 juin 2023
publication
Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody.
Lire plus05 avr. 2023
publication
SARS‐CoV‐2‐related bat virus behavior in human‐relevant models sheds light on the origin of COVID‐19
Lire plus01 avr. 2023
publication
Neutralization of zoonotic retroviruses by human antibodies: Genotype-specific epitopes within the receptor-binding domain from simian foamy virus.
Lire plus28 mars 2023
publication
Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein.
Lire plus06 mars 2023
publication
The crystal structure of a simian Foamy Virus receptor binding domain provides clues about entry into host cells.
Lire plus15 sept. 2022
event
“Structural biology of beneficial viruses: the anatomy of a flagellotropic bacteriophage and surprises in the architecture of flaviviruses.”
Lire plus04 juil. 2022
publication
Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.
Lire plus28 juin 2022
publication
Evolution and activation mechanism of the flavivirus class II membrane-fusion machinery.
Lire plus17 juin 2022
news
New publication – Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2
Lire plus24 mai 2022
publication
Dengue virus NS1 protein conveys pro-inflammatory signals by docking onto high-density lipoproteins.
Lire plus14 avr. 2022
08 avr. 2022
news
New publication – Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller
Lire plus12 mars 2022
publication
Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2.
Lire plus07 mars 2022
publication
Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller.
Lire plus01 févr. 2022
07 janv. 2022
publication
Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.
Lire plus09 déc. 2021
publication
The epitope arrangement on flavivirus particles contributes to Mab C10’s extraordinary neutralization breadth across Zika and dengue viruses.
Lire plus15 sept. 2021
01 sept. 2021
publication
Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling.
Lire plus08 juil. 2021
11 juin 2021
news
COVID-19: sensitivity of the Indian variant (B.1.617.2) to monoclonal antibodies and sera from convalescent and vaccinated individuals
Lire plus09 janv. 2021
project
PTR2020-353 ZOOFOAMENV – Host pathogens interactions in humans infected with zoonotic foamy viruses
Lire plus15 oct. 2020
02 sept. 2020
publication
A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations
Lire plus05 juin 2020
publication
A nicotinic hypothesis for Covid-19 with preventive and therapeutic implications.
Lire plus10 avr. 2020
07 févr. 2020
31 janv. 2020
30 janv. 2020
publication
Structure of the prefusion-locking broadly neutralizing antibody RVC20 bound to the rabies virus glycoprotein.
Lire plus06 déc. 2019
publication
X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications.
Lire plus08 févr. 2019
01 févr. 2019
event
Virology Department : PhD Thesis Defense “Structural and functional studies on human syncytins -Insights into the molecular mechanisms of placental cell-cell fusion” with Catharina Ruigrok
Lire plus23 févr. 2017
13 janv. 2017
06 janv. 2017
event
Conférence du Conseil Scientifique : Flavivirus structural heterogeneity: implications for entry, antibody neutralisation and vaccine design
Lire plus27 oct. 2015
11 sept. 2015
03 août 2015
04 juil. 2015
04 juil. 2015
04 juil. 2015
04 juil. 2015
04 juil. 2015
04 juil. 2015
04 juil. 2015
04 juil. 2015
04 juil. 2015
04 juil. 2015
11 mai 2015
23 avr. 2015
publication
A replication defect of pseudorabies virus induced by targeted α-helix distortion in the syntaxin-like bundle of glycoprotein H (V275P) is corrected by an adjacent compensatory mutation (V271A).
Lire plus04 févr. 2015
publication
X-ray structure of the pestivirus NS3 helicase and its conformation in solution
Lire plus15 déc. 2014
publication
A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus
Lire plus04 déc. 2014
03 déc. 2014
publication
Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein E2 recognized by broadly neutralizing antibodies
Lire plus12 nov. 2014
publication
Structure-based functional analyses of domains II and III of pseudorabies virus glycoprotein H.
Lire plus01 oct. 2014
publication
Robust and low cost uniform (15)N-labeling of proteins expressed in Drosophila S2 cells and Spodoptera frugiperda Sf9 cells for NMR applications.
Lire plus03 sept. 2014
publication
The highly conserved proline at position 438 in pseudorabies virus gH is important for regulation of membrane fusion.
Lire plus10 avr. 2014
18 oct. 2013
23 mai 2013
16 mai 2013
publication
Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape
Lire plus23 avr. 2013
06 janv. 2013
publication
Functional and evolutionary insight from the crystal structure of rubella virus protein E1
Lire plus21 déc. 2012
11 sept. 2012
01 mai 2012
publication
Crystal structure of the pestivirus envelope glycoprotein E(rns) and mechanistic analysis of its ribonuclease activity
Lire plus26 janv. 2012
02 janv. 2012
12 déc. 2011
publication
High-level secretion of recombinant monomeric murine and human single-chain Fv antibodies from Drosophila S2 cells
Lire plus02 déc. 2011
publication
Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus
Lire plus28 nov. 2011
publication
X-ray structure of the arenavirus glycoprotein GP2 in its postfusion hairpin conformation
Lire plus12 oct. 2011
publication
Peptides targeting the PDZ domain of PTPN4 are efficient inducers of glioblastoma cell death
Lire plus11 août 2011
13 déc. 2010
publication
Structure of a core fragment of glycoprotein H from pseudorabies virus in complex with antibody.
Lire plus08 déc. 2010
publication
Identification of new functional regions in hepatitis C virus envelope glycoprotein E2
Lire plus01 déc. 2010
publication
Glycoprotein organization of Chikungunya virus particles revealed by X-ray crystallography
Lire plus19 févr. 2010
publication
The disulfide bonds in glycoprotein E2 of hepatitis C virus reveal the tertiary organization of the molecule
Lire plus24 janv. 2010
publication
Efficient method for production of high yields of Fab fragments in Drosophila S2 cells.
Lire plus27 nov. 2009
publication
Crystal structure of a nucleocapsid-like nucleoprotein-RNA complex of respiratory syncytial virus
Lire plus24 juin 2009
30 avr. 2009
publication
The picobirnavirus crystal structure provides functional insights into virion assembly and cell entry
Lire plus01 juin 2007
01 oct. 2006
23 mai 2006
publication
Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak
Lire plus26 avr. 2005
publication