Ligne de temps

Félix Rey
Responsable de Structure
02 nov. 2023
publication

SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells.

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25 oct. 2023
publication

TMPRSS2 is a functional receptor for human coronavirus HKU1.

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18 sept. 2023
project

FURTHEST: Unraveling the Foamy Virus interactions with the host: insights into the molecular mechanisms of entry and neutralization

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21 août 2023
publication

New insight into flavivirus maturation from structure/function studies of the yellow fever virus envelope protein complex

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10 juil. 2023
publication

Qualitative monitoring of SARS-CoV-2 mRNA vaccination in humans using droplet microfluidics.

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14 juin 2023
publication

Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody.

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05 avr. 2023
publication

SARS‐CoV‐2‐related bat virus behavior in human‐relevant models sheds light on the origin of COVID‐19

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01 avr. 2023
publication

Neutralization of zoonotic retroviruses by human antibodies: Genotype-specific epitopes within the receptor-binding domain from simian foamy virus.

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28 mars 2023
publication

Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein.

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06 mars 2023
publication

The crystal structure of a simian Foamy Virus receptor binding domain provides clues about entry into host cells.

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15 sept. 2022
event

“Structural biology of beneficial viruses: the anatomy of a flagellotropic bacteriophage and surprises in the architecture of flaviviruses.”

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04 juil. 2022
publication

Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.

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28 juin 2022
publication

Evolution and activation mechanism of the flavivirus class II membrane-fusion machinery.

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17 juin 2022
news

New publication – Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2

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24 mai 2022
publication

Dengue virus NS1 protein conveys pro-inflammatory signals by docking onto high-density lipoproteins.

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14 avr. 2022
publication

Bat coronaviruses related to SARS-CoV-2 and infectious for human cells.

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08 avr. 2022
news

New publication – Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller

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12 mars 2022
publication

Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2.

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07 mars 2022
publication

Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller.

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01 févr. 2022
publication

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization.

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07 janv. 2022
publication

Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.

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09 déc. 2021
publication

The epitope arrangement on flavivirus particles contributes to Mab C10’s extraordinary neutralization breadth across Zika and dengue viruses.

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15 sept. 2021
project

Foamy virus Env protein – where virus meets the cells and host immune system

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01 sept. 2021
publication

Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling.

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08 juil. 2021
publication

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization.

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11 juin 2021
news

COVID-19: sensitivity of the Indian variant (B.1.617.2) to monoclonal antibodies and sera from convalescent and vaccinated individuals

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09 janv. 2021
project

PTR2020-353 ZOOFOAMENV – Host pathogens interactions in humans infected with zoonotic foamy viruses

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15 oct. 2020
publication

The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.

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02 sept. 2020
publication

A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations

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05 juin 2020
publication

A nicotinic hypothesis for Covid-19 with preventive and therapeutic implications.

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10 avr. 2020
project

CORONABODIES

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07 févr. 2020
news

RABIES : New perspectives for prevention and treatment

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31 janv. 2020
news

Coronavirus : Mobilisation Equipes de l’Institut Pasteur

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30 janv. 2020
publication

Structure of the prefusion-locking broadly neutralizing antibody RVC20 bound to the rabies virus glycoprotein.

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06 déc. 2019
publication

X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications.

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08 févr. 2019
team

Virologie

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01 févr. 2019
event

Virology Department : PhD Thesis Defense “Structural and functional studies on human syncytins -Insights into the molecular mechanisms of placental cell-cell fusion” with Catharina Ruigrok

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23 févr. 2017
publication

The Ancient Gamete Fusogen HAP2 Is a Eukaryotic Class II Fusion Protein.

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13 janv. 2017
event

SEMINAR OF THE VIROLOGY DEPARTMENT

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06 janv. 2017
event

Conférence du Conseil Scientifique : Flavivirus structural heterogeneity: implications for entry, antibody neutralisation and vaccine design

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27 oct. 2015
project

ERC-2013-ADG CELCELFUS

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11 sept. 2015
project

DENFREE consortium – Dengue Framework for Resisting Epidemics in Europe

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03 août 2015
project

Protein Data Bank depositions

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04 juil. 2015
project

Rubella virus E1 envelope glycoprotein

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04 juil. 2015
project

Respiratory Syncytial virus

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04 juil. 2015
project

Picobirnavirus capsid protein

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04 juil. 2015
project

Pestivirus

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04 juil. 2015
project

Herpesvirus

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04 juil. 2015
project

Hepatitis C virus

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04 juil. 2015
project

Dengue virus

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04 juil. 2015
project

Chikungunya virus

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04 juil. 2015
project

C. elegans Eff-1

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04 juil. 2015
project

Arenavirus

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11 mai 2015
team

Virologie structurale

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23 avr. 2015
publication

A replication defect of pseudorabies virus induced by targeted α-helix distortion in the syntaxin-like bundle of glycoprotein H (V275P) is corrected by an adjacent compensatory mutation (V271A).

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04 févr. 2015
publication

X-ray structure of the pestivirus NS3 helicase and its conformation in solution

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15 déc. 2014
publication

A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus

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04 déc. 2014
publication

Rubella virus: first calcium-requiring viral fusion protein

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03 déc. 2014
publication

Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein E2 recognized by broadly neutralizing antibodies

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12 nov. 2014
publication

Structure-based functional analyses of domains II and III of pseudorabies virus glycoprotein H.

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01 oct. 2014
publication

Robust and low cost uniform (15)N-labeling of proteins expressed in Drosophila S2 cells and Spodoptera frugiperda Sf9 cells for NMR applications.

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03 sept. 2014
publication

The highly conserved proline at position 438 in pseudorabies virus gH is important for regulation of membrane fusion.

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10 avr. 2014
publication

Structural basis of eukaryotic cell-cell fusion

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18 oct. 2013
publication

Gain-of-function research: unknown risks

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23 mai 2013
publication

Dengue virus: two hosts, two structures

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16 mai 2013
publication

Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape

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23 avr. 2013
publication

Alphavirus structure: activation for entry at the target cell surface

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06 janv. 2013
publication

Functional and evolutionary insight from the crystal structure of rubella virus protein E1

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21 déc. 2012
publication

SnapShot: Viral and eukaryotic protein fusogens

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11 sept. 2012
project

Chikungunya virus pathogenesis

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01 mai 2012
publication

Crystal structure of the pestivirus envelope glycoprotein E(rns) and mechanistic analysis of its ribonuclease activity

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26 janv. 2012
publication

Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody

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02 janv. 2012
publication

Virus entry: old viruses, new receptors.

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12 déc. 2011
publication

High-level secretion of recombinant monomeric murine and human single-chain Fv antibodies from Drosophila S2 cells

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02 déc. 2011
publication

Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus

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28 nov. 2011
publication

X-ray structure of the arenavirus glycoprotein GP2 in its postfusion hairpin conformation

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12 oct. 2011
publication

Peptides targeting the PDZ domain of PTPN4 are efficient inducers of glioblastoma cell death

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11 août 2011
publication

Class II enveloped viruses

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13 déc. 2010
publication

Structure of a core fragment of glycoprotein H from pseudorabies virus in complex with antibody.

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08 déc. 2010
publication

Identification of new functional regions in hepatitis C virus envelope glycoprotein E2

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01 déc. 2010
publication

Glycoprotein organization of Chikungunya virus particles revealed by X-ray crystallography

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19 févr. 2010
publication

The disulfide bonds in glycoprotein E2 of hepatitis C virus reveal the tertiary organization of the molecule

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24 janv. 2010
publication

Efficient method for production of high yields of Fab fragments in Drosophila S2 cells.

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27 nov. 2009
publication

Crystal structure of a nucleocapsid-like nucleoprotein-RNA complex of respiratory syncytial virus

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24 juin 2009
publication

Single-particle cryoEM reconstructions: meeting the challenge

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30 avr. 2009
publication

The picobirnavirus crystal structure provides functional insights into virion assembly and cell entry

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01 juin 2007
publication

Characterization of reemerging chikungunya virus

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01 oct. 2006
publication

Molecular gymnastics at the herpesvirus surface

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23 mai 2006
publication

Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak

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26 avr. 2005
publication

Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals

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