Timeline

Olivier Dussurget

Group Leader

30 Mar 2024

publication

Staphylococcus aureus NAD kinase is required for envelop and antibiotic stress responses.

27 Feb 2023

publication

Yersiniomics, a Multi-Omics Interactive Database for Yersinia Species.

15 Jan 2023

publication

Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.

05 Oct 2022

publication

The cnf1 gene is associated with an expanding Escherichia coli ST131 H30Rx/C2 subclade and confers a competitive advantage for gut colonization.

09 Sep 2022

project

NOVOPLASM – Novel perspective for cold plasma application in the treatment of severe and infected burn wounds

20 Jun 2022

publication

NAD kinase promotes Staphylococcus aureus pathogenesis by supporting production of virulence factors and protective enzymes.

09 May 2022

project

Clinical and bacterial determinants of Yersinia pestis bacteremia

01 Jan 2022

publication

Upward trend for “Microbes and Infection”.

05 Oct 2021

publication

Listeriolysin S: A bacteriocin from Listeria monocytogenes that induces membrane permeabilization in a contact-dependent manner.

16 Jun 2021

publication

Cold Atmospheric Plasma Promotes Killing of Staphylococcus aureus by Macrophages.

22 Oct 2020

publication

New Chemical Probe Targeting Bacterial NAD Kinase.

28 Aug 2020

team

Group : Bacterial Pathogenesis and Antibacterial Agents

01 Apr 2020

publication

Three decades of listeriology through the prism of technological advances.

13 Mar 2020

publication

From Substrate to Fragments to Inhibitor Active In Vivo against Staphylococcus aureus.

01 Jan 2020

publication

Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic Bacteria.

17 Dec 2019

publication

Ubiquitination of Listeria Virulence Factor InlC Contributes to the Host Response to Infection.

26 Nov 2019

publication

The in vivo ISGylome links ISG15 to metabolic pathways and autophagy upon Listeria monocytogenes infection.

13 Nov 2019

publication

A Listeria monocytogenes Bacteriocin Can Target the Commensal Prevotella copri and Modulate Intestinal Infection.

13 Sep 2019

project

Chronic carriage of CNF1-producing bacteria in the gut and development of colorectal cancer

29 Aug 2019

event

International Symposium in honor of Pascale Cossart

17 Jul 2019

event

7th International Symposium on Antimicrobial Peptides AMP2022

01 May 2019

publication

Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination, and diagnostics

01 Feb 2019

publication

Reassessing the role of internalin B in Listeria monocytogenes virulence using the epidemic strain F2365.

01 Jan 2019

publication

Real-Time Monitoring of Yersinia pestis Promoter Activity by Bioluminescence Imaging.

01 Jan 2019

publication

Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination and diagnostics

01 Jan 2018

publication

Editorial: Cell Signaling in Host-Pathogen Interactions: The Host Point of View.

16 Nov 2017

publication

Unraveling the evolution and coevolution of small regulatory RNAs and coding genes in Listeria.

31 Oct 2017

publication

OrfX, a Nucleomodulin Required for Listeria monocytogenes Virulence.

04 Apr 2017

publication

Listeriolysin S Is a Streptolysin S-Like Virulence Factor That Targets Exclusively Prokaryotic Cells In Vivo.

29 Nov 2016

publication

8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode.

17 May 2016

publication

Bacteriocin from epidemic Listeria strains alters the host intestinal microbiota to favor infection.

06 May 2016

news

A bacteriocin from epidemic Listeria strains alters the host intestinal microbiota to favor infection (PNAS May 2nd, 2016)

01 Jan 2016

publication

Cytosolic Innate Immune Sensing and Signaling upon Infection.

11 Aug 2015

publication

ISG15 counteracts Listeria monocytogenes infection.

03 Aug 2015

patent

NOVEL ANTIBACTERIAL COMPOUNDS

28 Jul 2015

project

Inhibitors of bacterial NAD kinases

11 May 2015

team

Yersinia

24 Nov 2014

team

Bacteria-Cell Interactions

01 Jan 2014

publication

The bacterial pathogen Listeria monocytogenes and the interferon family: type I, type II and type III interferons.

06 Jun 2012

publication

Screening and in situ synthesis using crystals of a NAD kinase lead to a potent antistaphylococcal compound.

01 Jan 2012

publication

The timing of IFNβ production affects early innate responses to Listeria monocytogenes and determines the overall outcome of lethal infection.

01 Jan 2012

publication

Both TLR2 and TRIF contribute to interferon-β production during Listeria infection.

01 Sep 2011

publication

OatA, a peptidoglycan O-acetyltransferase involved in Listeria monocytogenes immune escape, is critical for virulence.

01 Aug 2011

publication

Recruitment of the major vault protein by InlK: a Listeria monocytogenes strategy to avoid autophagy.

17 Jun 2011

publication

Identity, regulation and in vivo function of gut NKp46+RORγt+ and NKp46+RORγt- lymphoid cells.

01 Jun 2011

publication

LipA, a tyrosine and lipid phosphatase involved in the virulence of Listeria monocytogenes.

05 Oct 2010

publication

The Listeria monocytogenes InlC protein interferes with innate immune responses by targeting the I{kappa}B kinase subunit IKK{alpha}.

01 Aug 2010

publication

The Staphylococcus aureus epidermal cell differentiation inhibitor toxin promotes formation of infection foci in a mouse model of bacteremia.

01 Jun 2010

publication

Single-cell techniques using chromosomally tagged fluorescent bacteria to study Listeria monocytogenes infection processes.

01 May 2010

publication

The stress-induced virulence protein InlH controls interleukin-6 production during murine listeriosis.

01 Jan 2010

publication

Comparative analysis of the virulence of invertebrate and mammalian pathogenic bacteria in the oral insect infection model Galleria mellonella.

13 Nov 2009

publication

A trans-acting riboswitch controls expression of the virulence regulator PrfA in Listeria monocytogenes.

01 Jul 2009

publication

Characterization of a serine/threonine kinase involved in virulence of Staphylococcus aureus.

18 Jun 2009

publication

The Listeria transcriptional landscape from saprophytism to virulence.

01 Feb 2009

publication

The impact of growth history and flagellation on the adhesion of various Listeria monocytogenes strains to polystyrene.

01 Jan 2009

publication

Modeling human listeriosis in natural and genetically engineered animals.

01 Nov 2008

publication

Bioluminescent Aspergillus fumigatus, a new tool for drug efficiency testing and in vivo monitoring of invasive aspergillosis.

23 Oct 2008

publication

Conjugated action of two species-specific invasion proteins for fetoplacental listeriosis.

01 Sep 2008

publication

Rapid eradication of Listeria monocytogenes by moxifloxacin in a murine model of central nervous system listeriosis.

01 Aug 2008

publication

The DegU orphan response regulator of Listeria monocytogenes autorepresses its own synthesis and is required for bacterial motility, virulence and biofilm formation.

01 Jan 2008

publication

New insights into determinants of Listeria monocytogenes virulence.

01 Oct 2007

publication

Comparative transcriptome analysis of Listeria monocytogenes strains of the two major lineages reveals differences in virulence, cell wall, and stress response.

16 Jan 2007

publication

A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system.

20 Oct 2006

publication

Control of Listeria superoxide dismutase by phosphorylation.

05 Jun 2006

publication

Induction of transient macroapertures in endothelial cells through RhoA inhibition by Staphylococcus aureus factors.

15 Sep 2005

publication

Listeria monocytogenes ferritin protects against multiple stresses and is required for virulence.

01 Sep 2005

publication

VirR, a response regulator critical for Listeria monocytogenes virulence.

01 Apr 2005

publication

Translation elongation factor EF-Tu is a target for Stp, a serine-threonine phosphatase involved in virulence of Listeria monocytogenes.

01 Mar 2004

publication

Auto, a surface associated autolysin of Listeria monocytogenes required for entry into eukaryotic cells and virulence.

01 Jan 2004

publication

Molecular determinants of Listeria monocytogenes virulence.

01 Aug 2002

publication

Listeria monocytogenes bile salt hydrolase is a PrfA-regulated virulence factor involved in the intestinal and hepatic phases of listeriosis.

01 May 2002

publication

Surface proteins and the pathogenic potential of Listeria monocytogenes.

26 Oct 2001

publication

Comparative genomics of Listeria species.

01 Jan 2001

publication

Role of Mycobacterium tuberculosis copper-zinc superoxide dismutase.

01 Jun 1999

publication

Transcriptional control of the iron-responsive fxbA gene by the mycobacterial regulator IdeR.

01 Jan 1999

publication

Identification and characterization of two divergently transcribed iron regulated genes in Mycobacterium tuberculosis.

01 Sep 1998

publication

Interdependence of mycobacterial iron regulation, oxidative-stress response and isoniazid resistance.

01 Jan 1998

publication

Extra and intracellular expression of Mycobacterium tuberculosis genes.

01 Jan 1998

publication

Protective role of the Mycobacterium smegmatis IdeR against reactive oxygen species and isoniazid toxicity.

01 Jan 1998

publication

Genotypic methods for diagnosis of mycoplasmal infections in humans, animals, plants and cell cultures.

01 Nov 1996

publication

An ideR mutant of Mycobacterium smegmatis has derepressed siderophore production and an altered oxidative-stress response.

07 Nov 1995

publication

Genomic organization of the mycobacterial sigma gene cluster.

01 Feb 1995

publication

Advances in PCR-based detection of mycoplasmas contaminating cell cultures.

01 Mar 1994

publication

A little guide for advanced search:

Staphylococcus aureus NAD kinase is required for envelop and antibiotic stress responses.

Yersiniomics, a Multi-Omics Interactive Database for Yersinia Species.

Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.

The cnf1 gene is associated with an expanding Escherichia coli ST131 H30Rx/C2 subclade and confers a competitive advantage for gut colonization.

NOVOPLASM – Novel perspective for cold plasma application in the treatment of severe and infected burn wounds

NAD kinase promotes Staphylococcus aureus pathogenesis by supporting production of virulence factors and protective enzymes.

Clinical and bacterial determinants of Yersinia pestis bacteremia

Upward trend for “Microbes and Infection”.

Listeriolysin S: A bacteriocin from Listeria monocytogenes that induces membrane permeabilization in a contact-dependent manner.

Cold Atmospheric Plasma Promotes Killing of Staphylococcus aureus by Macrophages.

New Chemical Probe Targeting Bacterial NAD Kinase.

Group : Bacterial Pathogenesis and Antibacterial Agents

Three decades of listeriology through the prism of technological advances.

From Substrate to Fragments to Inhibitor Active In Vivo against Staphylococcus aureus.

Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic Bacteria.

Ubiquitination of Listeria Virulence Factor InlC Contributes to the Host Response to Infection.

The in vivo ISGylome links ISG15 to metabolic pathways and autophagy upon Listeria monocytogenes infection.

A Listeria monocytogenes Bacteriocin Can Target the Commensal Prevotella copri and Modulate Intestinal Infection.

Chronic carriage of CNF1-producing bacteria in the gut and development of colorectal cancer

International Symposium in honor of Pascale Cossart

7th International Symposium on Antimicrobial Peptides AMP2022

Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination, and diagnostics

Reassessing the role of internalin B in Listeria monocytogenes virulence using the epidemic strain F2365.

Real-Time Monitoring of Yersinia pestis Promoter Activity by Bioluminescence Imaging.

Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination and diagnostics

Editorial: Cell Signaling in Host-Pathogen Interactions: The Host Point of View.

Unraveling the evolution and coevolution of small regulatory RNAs and coding genes in Listeria.

OrfX, a Nucleomodulin Required for Listeria monocytogenes Virulence.

Listeriolysin S Is a Streptolysin S-Like Virulence Factor That Targets Exclusively Prokaryotic Cells In Vivo.

8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode.

Bacteriocin from epidemic Listeria strains alters the host intestinal microbiota to favor infection.

A bacteriocin from epidemic Listeria strains alters the host intestinal microbiota to favor infection (PNAS May 2nd, 2016)

Cytosolic Innate Immune Sensing and Signaling upon Infection.

ISG15 counteracts Listeria monocytogenes infection.

NOVEL ANTIBACTERIAL COMPOUNDS

Inhibitors of bacterial NAD kinases

Yersinia

Bacteria-Cell Interactions

The bacterial pathogen Listeria monocytogenes and the interferon family: type I, type II and type III interferons.

Screening and in situ synthesis using crystals of a NAD kinase lead to a potent antistaphylococcal compound.

The timing of IFNβ production affects early innate responses to Listeria monocytogenes and determines the overall outcome of lethal infection.

Both TLR2 and TRIF contribute to interferon-β production during Listeria infection.

OatA, a peptidoglycan O-acetyltransferase involved in Listeria monocytogenes immune escape, is critical for virulence.

Recruitment of the major vault protein by InlK: a Listeria monocytogenes strategy to avoid autophagy.

Identity, regulation and in vivo function of gut NKp46+RORγt+ and NKp46+RORγt- lymphoid cells.

LipA, a tyrosine and lipid phosphatase involved in the virulence of Listeria monocytogenes.

The Listeria monocytogenes InlC protein interferes with innate immune responses by targeting the I{kappa}B kinase subunit IKK{alpha}.

The Staphylococcus aureus epidermal cell differentiation inhibitor toxin promotes formation of infection foci in a mouse model of bacteremia.

Single-cell techniques using chromosomally tagged fluorescent bacteria to study Listeria monocytogenes infection processes.

The stress-induced virulence protein InlH controls interleukin-6 production during murine listeriosis.

Comparative analysis of the virulence of invertebrate and mammalian pathogenic bacteria in the oral insect infection model Galleria mellonella.

A trans-acting riboswitch controls expression of the virulence regulator PrfA in Listeria monocytogenes.

Characterization of a serine/threonine kinase involved in virulence of Staphylococcus aureus.

The Listeria transcriptional landscape from saprophytism to virulence.

The impact of growth history and flagellation on the adhesion of various Listeria monocytogenes strains to polystyrene.

Modeling human listeriosis in natural and genetically engineered animals.

Bioluminescent Aspergillus fumigatus, a new tool for drug efficiency testing and in vivo monitoring of invasive aspergillosis.

Conjugated action of two species-specific invasion proteins for fetoplacental listeriosis.

Rapid eradication of Listeria monocytogenes by moxifloxacin in a murine model of central nervous system listeriosis.

The DegU orphan response regulator of Listeria monocytogenes autorepresses its own synthesis and is required for bacterial motility, virulence and biofilm formation.

New insights into determinants of Listeria monocytogenes virulence.

Comparative transcriptome analysis of Listeria monocytogenes strains of the two major lineages reveals differences in virulence, cell wall, and stress response.

A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system.

Control of Listeria superoxide dismutase by phosphorylation.

Induction of transient macroapertures in endothelial cells through RhoA inhibition by Staphylococcus aureus factors.

Listeria monocytogenes ferritin protects against multiple stresses and is required for virulence.

VirR, a response regulator critical for Listeria monocytogenes virulence.

Translation elongation factor EF-Tu is a target for Stp, a serine-threonine phosphatase involved in virulence of Listeria monocytogenes.

Auto, a surface associated autolysin of Listeria monocytogenes required for entry into eukaryotic cells and virulence.

Molecular determinants of Listeria monocytogenes virulence.

Listeria monocytogenes bile salt hydrolase is a PrfA-regulated virulence factor involved in the intestinal and hepatic phases of listeriosis.

Surface proteins and the pathogenic potential of Listeria monocytogenes.

Comparative genomics of Listeria species.

Role of Mycobacterium tuberculosis copper-zinc superoxide dismutase.

Transcriptional control of the iron-responsive fxbA gene by the mycobacterial regulator IdeR.

Identification and characterization of two divergently transcribed iron regulated genes in Mycobacterium tuberculosis.

Interdependence of mycobacterial iron regulation, oxidative-stress response and isoniazid resistance.

Extra and intracellular expression of Mycobacterium tuberculosis genes.

Protective role of the Mycobacterium smegmatis IdeR against reactive oxygen species and isoniazid toxicity.