Timeline

Matthew Albert
Permanent Researcher
30 May 2019
publication

Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection

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18 Feb 2019
publication

Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth

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24 Sep 2018
publication

Lymphocytes are a major source of circulating soluble dipeptidyl peptidase 4

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27 Jul 2018
publication

Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines

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05 Jul 2018
publication

Interplay of DDP4 and IP-10 as a Potential Mechanism for Cell Recruitment to Tuberculosis Lesions

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01 Jul 2018
publication

Systemic DPP4 activity is reduced during primary HIV-1 infection and is associated with intestinal RORC CD4 cell levels: a surrogate marker candidate of HIV-induced intestinal damage

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19 Jun 2018
publication

Plasmacytoid dendritic cells control dengue and Chikungunya virus infections via IRF7-regulated interferon responses

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10 May 2018
publication

Autophagy diminishes the early interferon-β response to influenza A virus resulting in differential expression of interferon-stimulated genes

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03 Apr 2018
publication

Development and clinical validation of the Genedrive point-of-care test for qualitative detection of hepatitis C virus

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22 Mar 2018
publication

T-cell biomarkers for diagnosis of tuberculosis: candidate evaluation by a simple whole blood assay for clinical translation

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23 Feb 2018
publication

Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors

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27 Dec 2017
publication

Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges

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01 Dec 2017
publication

Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice

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29 Nov 2017
publication

CXCR3/CXCL10 Axis Shapes Tissue Distribution of Memory Phenotype CD8 T Cells in Nonimmunized Mice

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21 Sep 2017
publication

Standardized whole blood stimulation improves immunomonitoring of induced immune responses in multi-center study

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06 Sep 2017
publication

An in vitro diagnostic certified point of care single nucleotide test for IL28B polymorphisms

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31 Aug 2017
publication

Development of a bead-based multiplex assay for the analysis of the serological response against the six pathogens HAV, HBV, HCV, CMV, T. gondii and H. pylori

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30 Aug 2017
publication

Hepatitis E virus-induced primary cutaneous CD30(+) T cell lymphoproliferative disorder

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13 Jul 2017
publication

Deconvolution of the Response to Bacillus Calmette-Guérin Reveals NF-κB-Induced Cytokines As Autocrine Mediators of Innate Immunity

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18 Apr 2017
publication

Detection of interferon alpha protein reveals differential levels and cellular sources in disease

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13 Mar 2017
publication

Dying cells actively regulate adaptive immune responses

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28 Feb 2017
publication

Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents

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20 Oct 2016
publication

Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations

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14 Oct 2016
publication

Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses

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22 Sep 2016
publication

Bladder catheterization increases susceptibility to infection that can be prevented by prophylactic antibiotic treatment

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26 Aug 2016
news

New publication for Milieu Intérieur

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25 Aug 2016
publication

Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses

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10 Aug 2016
publication

Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset

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27 Jul 2016
publication

Comment on “NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis”

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22 Jun 2016
project

Think tank: Cancer

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01 Jun 2016
publication

Inhibition of DPP4 activity in humans establishes its in vivo role in CXCL10 post-translational modification: prospective placebo-controlled clinical studies

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24 Mar 2016
publication

Protein biomarkers discriminate Leishmania major-infected and non-infected individuals in areas endemic for cutaneous leishmaniasis

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29 Jan 2016
event

Milieu Intérieur Scientific Advisory Board

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01 Jan 2016
publication

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

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21 Dec 2015
publication

In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity

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15 Dec 2015
publication

Impact of IL28B, APOH and ITPA Polymorphisms on Efficacy and Safety of TVR- or BOC-Based Triple Therapy in Treatment-Experienced HCV-1 Patients with Compensated Cirrhosis from the ANRS CO20-CUPIC Study

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14 Dec 2015
publication

Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing

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13 Dec 2015
publication

Harnessing the Host Immune Response to Infection – BCG Immunotherapy for Bladder Cancer

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24 Sep 2015
publication

RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8+ T cells

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10 Sep 2015
event

Milieu Intérieur speed-dating symposium

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10 Sep 2015
project

Functional immune response to Mycobacteria tuberculosis derived antigen

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28 Aug 2015
publication

Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway

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22 Jul 2015
project

1,000 healthy donors

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16 Jul 2015
publication

Macrophages Subvert Adaptive Immunity to Urinary Tract Infection

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15 Jun 2015
publication

Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy

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03 Jun 2015
publication

Plasma biomarkers discriminate clinical forms of multiple sclerosis

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11 May 2015
team

Immunobiology of Dendritic Cells

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23 Jan 2015
publication

Plasma apolipoprotein H limits HCV replication and associates with response to NS3 protease inhibitors-based therapy

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07 Jan 2015
publication

Automated flow cytometric analysis across large numbers of samples and cell types

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06 Jan 2015
publication

Semi-automated and standardized cytometric procedures for multi-panel and multi-parametric whole blood immunophenotyping

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03 Jan 2015
publication

The Milieu Intérieur study – an integrative approach for study of human immunological variance

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10 Nov 2014
publication

Baseline sensitivity of T cells to alpha-IFN correlates with sustained virological response to IFN-based triple therapy in HCV infection

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25 Jul 2014
publication

Summary of the 8th Annual Bladder Cancer Think Tank: Collaborating to move research forward

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30 Jun 2014
publication

Local immune response to injection of Plasmodium sporozoites into the skin

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06 Jun 2014
publication

RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis

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04 Jun 2014
publication

Apolipoprotein H expression is associated with IL28B genotype and viral clearance in hepatitis C virus infection

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19 May 2014
publication

Truncated CXCL10 is associated with failure to achieve spontaneous clearance of acute hepatitis C infection

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20 Mar 2014
publication

Functional analysis via standardized whole-blood stimulation systems defines the boundaries of a healthy immune response to complex stimuli

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18 Feb 2014
publication

The ABCs of viral hepatitis that define biomarker signatures of acute viral hepatitis

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28 Nov 2013
publication

Low DPP4 expression and activity in multiple sclerosis

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21 Nov 2013
publication

Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia

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21 Nov 2013
publication

Widespread mitochondrial depletion via mitophagy does not compromise necroptosis

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07 May 2013
publication

CXCL10 antagonism and plasma sDPPIV correlate with increasing liver disease in chronic HCV genotype 4 infected patients

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21 Mar 2013
publication

Chikungunya virus-associated long-term arthralgia: a 36-month prospective longitudinal study

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28 Feb 2013
publication

Frequent transient hepatitis C viremia without seroconversion among healthcare workers in Cairo, Egypt

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25 Feb 2013
publication

BCG-mediated bladder cancer immunotherapy: identifying determinants of treatment response using a calibrated mathematical model

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01 Jan 2013
publication

Tracking antigen-specific CD8⁺ T cells using MHC class I multimers

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15 Nov 2012
publication

Dissecting T cell contraction in vivo using a genetically encoded reporter of apoptosis

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01 Nov 2012
publication

Litchi-associated acute encephalitis in children, Northern Vietnam, 2004-2009

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12 Oct 2012
publication

Subcapsular sinus macrophages promote NK cell accumulation and activation in response to lymph-borne viral particles

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27 Jul 2012
publication

Chikungunya-induced cell death is limited by ER and oxidative stress-induced autophagy

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01 Jun 2012
publication

Preexisting BCG-specific T cells improve intravesical immunotherapy for bladder cancer

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02 May 2012
publication

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes

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16 Apr 2012
publication

Chikungunya virus-induced autophagy delays caspase-dependent cell death

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01 Apr 2012
publication

Guidelines for the use and interpretation of assays for monitoring autophagy

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28 Mar 2012
publication

Antigen Cross-Priming of Cell-Associated Proteins is Enhanced by Macroautophagy within the Antigen Donor Cell

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27 Feb 2012
publication

Cutting edge: independent roles for IRF-3 and IRF-7 in hematopoietic and nonhematopoietic cells during host response to Chikungunya infection

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01 Jan 2012
publication

Discrimination of agonist and antagonist forms of CXCL10 in biological samples

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01 Jan 2012
publication

Mathematical model of tumor immunotherapy for bladder carcinoma identifies the limitations of the innate immune response

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08 Dec 2011
publication

Immunization route dictates cross-priming efficiency and impacts the optimal timing of adjuvant delivery

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28 Oct 2011
publication

Dying to replicate: the orchestration of the viral life cycle, cell death pathways, and immunity

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20 Oct 2011
publication

ISG15 is critical in the control of Chikungunya virus infection independent of UbE1L mediated conjugation

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01 Sep 2011
publication

Simultaneous assessment of autophagy and apoptosis using multispectral imaging cytometry

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01 Aug 2011
publication

Cutting Edge: A dual role for type I IFNs during polyinosinic-polycytidylic acid-induced NK cell activation

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15 May 2011
publication

Visualizing the innate and adaptive immune responses underlying allograft rejection by two-photon microscopy

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04 May 2011
publication

Identification of a novel neuropathogenic Theiler’s murine encephalomyelitis virus

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21 Apr 2011
publication

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

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01 Apr 2011
publication

Interferon induced protein 10 remains a useful biomarker of treatment failure in patients stratified for the interleukin-28B rs12979860 haplotype

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17 Feb 2011
publication

Innate sensing of HIV-infected cells

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22 Dec 2010
publication

Evidence for an antagonist form of the chemokine CXCL10 in patients chronically infected with HCV

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19 Oct 2010
publication

Circulating plasmacytoid dendritic cells in acutely infected patients with hepatitis C virus genotype 4 are normal in number and phenotype

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24 Sep 2010
publication

Visualizing the functional diversification of CD8+ T cell responses in lymph nodes

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01 Sep 2010
publication

Harnessing naturally occurring tumor immunity: a clinical vaccine trial in prostate cancer

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01 Jul 2010
publication

Biology and pathogenesis of chikungunya virus

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01 Apr 2010
publication

Signal 0 for guided priming of CTLs: NKT cells do it too

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03 Mar 2010
publication

Enumeration of human antigen-specific naive CD8+ T cells reveals conserved precursor frequencies

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18 Feb 2010
publication

A whodunit: an appointment with death

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01 Feb 2010
publication

Type I IFN controls chikungunya virus via its action on nonhematopoietic cells

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01 Jan 2010
publication

Muscle resident macrophages control the immune cell reaction in a mouse model of notexin-induced myoinjury

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01 Dec 2009
publication

Immunosuppressive signature of cutaneous Mycobacterium ulcerans infection in the peripheral blood of patients with buruli ulcer disease

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12 May 2009
publication

Orchestration of the immune response by dendritic cells

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23 Feb 2009
publication

Molecular analyte profiling of the early events and tissue conditioning following intravesical bacillus calmette-guerin therapy in patients with superficial bladder cancer

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20 Feb 2009
publication

Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells

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29 Sep 2008
publication

Plasmacytoid dendritic cells move down on the list of suspects: in search of the immune pathogenesis of chronic hepatitis C

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01 Sep 2008
publication

Antigen persistence is required for dendritic cell licensing and CD8+ T cell cross-priming

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01 Sep 2008
publication

Selection of high-avidity CD8 T cells correlates with control of hepatitis C virus infection

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01 Feb 2008
publication

A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease

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24 Sep 2007
publication

Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients

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12 Sep 2007
publication

Gamma c cytokines condition the progressive differentiation of CD4+ T cells

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01 Jun 2007
publication

Characterization of reemerging chikungunya virus

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21 May 2007
publication

Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone

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15 May 2007
publication

Cutting edge: cross-presented intracranial antigen primes CD8+ T cells

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03 Oct 2006
publication

Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-alpha/beta on antigen cross-presentation

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15 Jun 2006
publication

IL-2 is required for the activation of memory CD8+ T cells via antigen cross-presentation

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10 Nov 2005
publication

Effective treatment of erythema nodosum leprosum with thalidomide is associated with immune stimulation

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31 Oct 2005
publication

Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes

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27 Jun 2005
publication

Normal functional capacity in circulating myeloid and plasmacytoid dendritic cells in patients with chronic hepatitis C

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09 Jun 2005
publication

A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation

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26 Apr 2005
publication

Apoptotic cells deliver processed antigen to dendritic cells for cross-presentation

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01 Mar 2004
publication

Death-defying immunity: do apoptotic cells influence antigen processing and presentation?

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15 Jan 2004
publication

The opsonin MFG-E8 is a ligand for the alphavbeta5 integrin and triggers DOCK180-dependent Rac1 activation for the phagocytosis of apoptotic cells

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01 Jan 2004
publication

Immune response against dying tumor cells

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01 Jan 2004
publication

Paraneoplastic neurological degenerations: keys to tumour immunity

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01 Jan 2004
publication

Effective antigen cross-presentation by prostate cancer patients’ dendritic cells: implications for prostate cancer immunotherapy

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02 Oct 2003
publication

Presence of functional dendritic cells in patients chronically infected with hepatitis C virus

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01 Nov 2001
publication

Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells

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01 Aug 2000
publication

cdr2-specific CTLs are detected in the blood of all patients with paraneoplastic cerebellar degeneration analyzed

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15 Apr 2000
publication

Cdr2, a target antigen of naturally occuring human tumor immunity, is widely expressed in gynecological tumors

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01 Feb 2000
publication

Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells

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01 Jan 2000
publication

Detection and treatment of activated T cells in the cerebrospinal fluid of patients with paraneoplastic cerebellar degeneration

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01 Nov 1998
publication

Tumor-specific killer cells in paraneoplastic cerebellar degeneration

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01 Oct 1998
publication

Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes

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01 Mar 1998
publication

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

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