Scientific activities of the Microbial Evolutionary Genomics Unit are centered on the bioinformatics and biostatistics analysis of genomes, at the crossroads of molecular evolution, population genetics, molecular epidemiology, and molecular genetics. We also develop some translational aspects related with the study of the diversity of bacterial pathogens.
We focus on four major questions:
- How and why are genomes organized?
- How are such organizational features evolving in face of the extensive genome dynamics?
- What are the roles of mobile elements in the evolution of the host genomes?
- What is the interplay between genome dynamics and bacterial pathogen emergence at the microevolutionary and epidemiological scale?