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© Institut Pasteur
Cells infected for 24 hrs with C. Trachomatis. The cell nuclei are labelled in blue, the bacteria appear yellow, within the inclusion lumen. A bacterial protein secreted out the inclusion into the host cytoplasm id labelled in red.

About

Our group studies the composition and molecular architecture of protein complexes involved in central metabolism in Actinobacteria, and the signaling pathways and/or allosteric mechanisms that contribute to their regulation. The objective is to shed light on the mechanisms that underlie the metabolic plasticity of the members of this phylum. Our experimental approaches involve the integrative structural biology of large metabolic complexes from the non-pathogenic species Corynebacterium glutamicum, a well-known workhorse for the biotech industry, but we are also interested in structural enzymology for drug design purposes, especially for targets from Mycobacterium tuberculosis. More information about our current activities can be found on the SUPERCPLX and METACTINO project pages.

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Contact

Phone: +33-1-45688608 Email: marco.bellinzoni@pasteur.fr Address 25-28 Rue du Docteur Roux 75015, Paris France