Philippe Bousso

To fight cancer or infections, a variety of immune cells are engaged in a tremendously complex, yet highly coordinated sequence of cellular processes. This coordination is enforced by distinct mechanisms of cellular communication allowing […]

The malignant transformation of cells translates into a major worldwide health, social and economic burden. Efforts to define the etiology of cancer, along with the development of new therapeutic approaches to treat them, would […]

The immune system is made up of specialized cells and tissues that act together to fight microbial infections and survey the body for malignant transformation. Immune responses are highly orchestrated and dynamic events that […]

Adaptive immune responses are initiated in secondary lymphoid organs through cellular interactions between antigen-specific T cells and antigen-presenting dendritic cells. One of the aim of our lab is to better understand how T cells […]

Intracellular pathogens have developed strategies to survive in infected cells and reduce their recognition by the innate and adaptive immune systems. Our lab wishes to define the mechanisms influencing the recognition of infected cells […]

Transplant rejection involves a coordinated attack of donor cells by the innate and the adaptive immune system of the host. To gain insight into this dynamic process, we have developed an ear skin graft […]

Cytotoxic T cells and NK cells (CTLs) are key players of anti-tumor immune responses. Despite our fundamental knowledge on the interplay between the immune system and tumor microenvironments, we have a poor understanding on […]

The Dynamic In Situ Cytometry (DISC) is a new approach that combines advantages of both intravital imaging and flow cytometry analysis. With the help of the custom designed DISCit software, the DISC provides the opportunity […]