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  • Permanent Researcher
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  • PhD Student
  • Physician
  • Post-doc
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  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
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Scientific Fields
Diseases
Organisms
Applications
Technique

About

 

Our group is interested in the development and evolution of brain anatomy. Our main tools are mathematical modelling, magnetic resonance imaging and human genetics. We develop computational neuroanatomy methods base on our theoretical models which we use to analyse the normal diversity of human brain anatomy, as well as to look for differences associated with neurodevelopmental pathologies. We are particularly interested in Autism Spectrum Disorders.

Projects

Project
Ongoing
11 Members

PARIS: Paris Autism Research International Sib-Pair Study

Thomas Bourgeron (PI)

The Paris Autism Research International Sib-pair (PARIS) Study has been launched as a collaborative project by Prof. M. Leboyer (Paris) and Prof. C. Gillberg (Göteborg) in the 2000s. Its main goal is to join […]
Project
Ongoing
3 Members

Tools for computational Neuroanatomy

Roberto Toro (PI)

We implement and develop data analysis pipelines to process large neuroimaging-genetics datasets, and participate in the analysis of several very large international consortia. We have developed online and offline interactive tools to examine the […]
Project
Ongoing
3 Members

Genomic architecture of normal and pathological human neuroanatomical diversity

Roberto Toro (PI)

Human brain anatomy is strikingly diverse and highly inheritable: genetic factors may explain up to 80% of its variability. Genome-wide scans looking for associations between genomic polymorphism and neuroanatomical variability identify, however, just a […]
Project
Ongoing
2 Members

Morphogenesis of neocortical organisation: theoretical and animal models

Roberto Toro (PI)

Neocortical folding is one of the most intriguing characteristics of the mammalian brain. Their pattern is very distinctive for different species, and there seems to be a remarkable relationship between convolutions and the architectonic […]
Project
Ongoing
5 Members

Patients et chercheurs vers un nouveau dialogue

Clementine Schilte (PI)

Afin de mieux répondre aux défis de la santé de demain, il est primordial de faire participer les patients aux différentes étapes de la recherche. Cette participation peut avoir lieu à toutes les étapes […]
Project
Ongoing
18 Members

Background on the genetics of ASD

Thomas Bourgeron (PI)

Autism spectrum disorders (ASD) are a heterogeneous group of pervasive neurodevelopmental disorders affecting approximately 1% of the population. The diagnosis of ASD is based on impairments in reciprocal social communication and stereotyped behaviors. Behind […]
Project
Ongoing
17 Members

Phelan-McDermid Syndrome: from mechanisms to treatments

Thomas Bourgeron (PI)

Our team identified the first mutations in the SHANK3 gene, showing it’s role in autism and Phelan-McDermid Syndrome (PMS). Thanks to a donation from the French Association of Phelan-McDermid Syndrome, we will continue the […]
Project
Completed
14 Members

Imaginons la recherche

Clementine Schilte (PI)

“Imaginons la recherche” is a project for supporting structural change in research organisations to promote Responsible Research and Innovation (RRI) as defined by the european commission : Public engagement (outreach & citizen science) Gender […]
Project
Ongoing
5 Members

Brain imaging and genetics

Thomas Bourgeron (PI)

Our group is exploring the human brain using Magnetic Resonance Imaging (MRI) and electroencephalogram (EEG). These approaches are combined with our genetic data in order to better understand the genetic and phenotypic diversity of […]

Software

Software
Ongoing
2 Members

BrainBox

Roberto Toro (PI)

BrainBox (http://brainbox.pasteur.fr) is a web application developed by the Groupe de Neuroanatomie appliquée et théorique de l’Unité de génétique humaine et fonctions cognitives. BrainBox lets you visualise and segment collaboratively any brain MRI dataset available […]
Software
Ongoing
2 Members

MicroDraw

Roberto Toro (PI)

MicroDraw is a web application to visualise and annotate collaboratively high resolution histology data. Annotations are vectorial, and you can use boolean operations to combine, subtract and split regions. You can point MicroDraw to […]
Software
Ongoing
2 Members

Brain Catalogue

Roberto Toro (PI)

The Brain Catalogue is a collaborative platform for comparative neuroanatomy. Our aim is to celebrate the diversity of the vertebrate brain by making high quality data, open and freely available to everyone. You can […]
Software
Ongoing
2 Members

BrainSpell

Roberto Toro (PI)

BrainSpell is a web platform for the collaborative annotation of the neuroimaging literature. You can use BrainSpell here: http://brainspell.pasteur.fr

Publications

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