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  • Visiting Scientist
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  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
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About

I currently lead a junior group in the Virology department of Institut Pasteur.

My research interests lie in RNA virus discovery, emergence, transmission, and evolution. Within the group, we use viral genomics to study evolutionary processes of RNA viruses, with a focus on respiratory viruses and arboviruses.

We combine molecular epidemiology studies thanks to amazing collaborations within the Institut Pasteur International Network and experimental work, both in vitro and in vivo. We work a lot with our great colleagues at the Mouse Genetics laboratory, at the Structural virology unit and the Virus and Immunity Unit.

Transversal Projects

Pasteur International Center for Research on Emerging Infectious Diseases

We established an Emerging Infectious Disease Research Center in Southeast Asia and West/Central Africa with an inter-continental one-health approach designed to improve the capacity to respond rapidly and effectively to outbreaks. We built on […]

INCEPTION – Institut Convergence for the study of Emergence of Pathology Through Individuals and Populations

IINCEPTION Goal The Inception aims to develop a core structure to mobilize data resources, numerical sciences, and fundamental experimental biology in various health issues (Official website here: https://www.inception-program.fr/en). The inception program uses Integrative Biology, […]

LabEx IBEID – Integrative Biology of Emerging Infectious Diseases

Presentation The aim of the Integrative Biology of Emerging Infectious Diseases (IBEID) project, coordinated by Professors Philippe Sansonetti and Pascale Cossart and currently coordinated by Carla Saleh and Philippe Bastin, is to develop a […]

Projects

Project
Ongoing
7 Members

Mouse models for Covid-19

Xavier Montagutelli (PI)

Mice are not naturally susceptible to SARS-CoV-2 due to poor binding of the virus spike to the mouse cellular receptor ACE2. We have developed a mouse-adapted strain of SARS-CoV-2 which efficiently replicates in the […]
Project
Ongoing
4 Members

Evolutionary Mechanisms underlying Yellow fever Resurgence in Africa – ANR JCJC

Etienne Simon-Loriere (PI)

Arthropod-borne viruses (arboviruses) pose a major threat to public health worldwide and are continuously (re-)emerging or spreading to uninfected areas. Recent examples notably include dengue, Chikungunya, yellow fever, and Zika virus disease. In addition […]
Project
Ongoing
5 Members

Study of immune crosstalk in COVID-19 COVIMUNE

Anavaj Sakuntabhai (PI)

Our overall goal is to understand the cellular and molecular aspects of immune response to SARS-CoV-2 virus in terms of activation of over-reactive immunity and induction of immune protection. COVIMUNE is designed to target […]
Project
Ongoing
8 Members

Host genetic susceptibility to Zika virus

Xavier Montagutelli (PI)

Zika virus is an arbovirus responsible for recent epidemics in Polynesia and in the Americas. Clinical descriptions range from mild flu-like syndromes to rare but severe neurological complications such as Guillain-Barré syndrome and encephalitis […]
Project
Ongoing
34 Members

Welcome to the Nanopore User Group at Institut Pasteur webpage

Chiara Crestani (PI)

About the Nanopore User Group: The Nanopore User Group at Institut Pasteur was established in 2019 with the primary goal of fostering collaboration, sharing knowledge, and advancing the application of Oxford Nanopore Technologies (ONT) […]
Project
Ongoing
6 Members

MICROTONE – Microbial and viral circulations among people and wild and domesticated animals in an ecotone, Democratic Republic of Congo

Tamara Giles-Vernick (PI)

Zoonotic transmissions are a major global health risk, with human-animal contact frequently raised as a driver of emergence. Studies of zoonotic transmission risks are often piecemeal, targeting bushmeat, specific animal reservoirs, or single pathogens. […]

CV

Maîtrise/D.E.A. (Masters) Microbiology – Basic virology , 2004. Université Paris VII – Denis Diderot, France PhD in Virology and Molecular Biology, 2009. Université Paris VI – Pierre et Marie Curie, France. Laboratory of Matteo Negroni. Postdoctoral Fellow, 2009-2012. Laboratory of Edward C. Holmes , The Pennsylvania State University, USA.

Publications

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