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  • PhD Student
  • Physician
  • Post-doc
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  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
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  • Honorary President of the Departement
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About

I currently lead a junior group in the Virology department of Institut Pasteur. My research interests lie in RNA virus discovery, emergence, transmission, and evolution. Within the group, we use viral genomics to study evolutionary processes of RNA viruses, with a focus on arboviruses such as dengue and Zika. Like many others, we are also contributing to the fight against COVID-19. We combine molecular epidemiology studies thanks to amazing collaborations within the Institut Pasteur International Network and experimental work, both in vitro and in vivo. We work a lot with our great colleagues at the Mouse Genetics laboratory and the French National Reference Center for viruses of respiratory infections.

Transversal Projects

INCEPTION – Institut Convergence for the study of Emergence of Pathology Through Individuals and Populations

IINCEPTION Goal The Inception’s goal is to develop a core structure to mobilize data resources, numerical sciences, and fundamental experimental biology in a range of health issues (Official website here : https://www.inception-program.fr/en). Inception program […]

LabEx IBEID – Integrative Biology of Emerging Infectious Diseases

Presentation The aim of the Integrative Biology of Emerging Infectious Diseases (IBEID) project, coordinated by Professors Philippe Sansonetti and Pascale Cossart, is to develop a structure to anticipate and tackle emerging infectious diseases (EIDs). […]

Projects

Project
Ongoing
7 Members

Mouse models for Covid-19

Xavier Montagutelli (PI)

Mice are not naturally susceptible to SARS-CoV-2 due to poor binding of the virus spike to the mouse cellular receptor ACE2. We have developed a mouse-adapted strain of SARS-CoV-2 which efficiently replicates in the […]
Project
Ongoing
4 Members

Evolutionary Mechanisms underlying Yellow fever Resurgence in Africa – ANR JCJC

Etienne Simon-Loriere (PI)

Arthropod-borne viruses (arboviruses) pose a major threat to public health worldwide and are continuously (re-)emerging or spreading to uninfected areas. Recent examples notably include dengue, Chikungunya, yellow fever, and Zika virus disease. In addition […]
Project
Ongoing
5 Members

Study of immune crosstalk in COVID-19 COVIMUNE

Anavaj Sakuntabhai (PI)

Our overall goal is to understand the cellular and molecular aspects of immune response to SARS-CoV-2 virus in terms of activation of over-reactive immunity and induction of immune protection. COVIMUNE is designed to target […]
Project
Ongoing
9 Members

Host genetic susceptibility to Zika virus

Xavier Montagutelli (PI)

Zika virus is an arbovirus responsible for recent epidemics in Polynesia and in the Americas. Clinical descriptions range from mild flu-like syndromes to rare but severe neurological complications such as Guillain-Barré syndrome and encephalitis […]
Project
Ongoing
16 Members

Pasteur International Center for Research on Emerging Infectious Diseases

Anavaj Sakuntabhai (PI)

We established an Emerging Infectious Disease Research Center in Southeast Asia and West/Central Africa with an inter-continental one-health approach designed to improve the capacity to respond rapidly and effectively to outbreaks. We built on […]
Project
Ongoing
6 Members

MICROTONE – Microbial and viral circulations among people and wild and domesticated animals in an ecotone, Democratic Republic of Congo

Tamara Giles-Vernick (PI)

Zoonotic transmissions are a major global health risk, with human-animal contact frequently raised as a driver of emergence. Studies of zoonotic transmission risks are often piecemeal, targeting bushmeat, specific animal reservoirs, or single pathogens. […]

CV

Maîtrise/D.E.A. (Masters) Microbiology – Basic virology , 2004. Université Paris VII – Denis Diderot, France PhD in Virology and Molecular Biology, 2009. Université Paris VI – Pierre et Marie Curie, France. Laboratory of Matteo Negroni. Postdoctoral Fellow, 2009-2012. Laboratory of Edward C. Holmes , The Pennsylvania State University, USA.

Publications

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