I currently lead a junior group in the Virology department of Institut Pasteur. My research interests lie in RNA virus discovery, emergence, transmission, and evolution. Within the group, we use viral genomics to study evolutionary processes of RNA viruses, with a focus on arboviruses such as dengue and Zika. Like many others, we are also contributing to the fight against COVID-19. We combine molecular epidemiology studies thanks to amazing collaborations within the Institut Pasteur International Network and experimental work, both in vitro and in vivo. We work a lot with our great colleagues at the Mouse Genetics laboratory and the French National Reference Center for viruses of respiratory infections.
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Maîtrise/D.E.A. (Masters) Microbiology – Basic virology , 2004. Université Paris VII – Denis Diderot, France PhD in Virology and Molecular Biology, 2009. Université Paris VI – Pierre et Marie Curie, France. Laboratory of Matteo Negroni. Postdoctoral Fellow, 2009-2012. Laboratory of Edward C. Holmes , The Pennsylvania State University, USA.
Publications
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2022Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2., J Exp Med 2022 Jul; 219(7): .
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2022Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2, J Exp Med . 2022 Jul 4;219(7):e20220638. doi: 10.1084/jem.20220638. Epub 2022 Jun 15. .
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2022Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen., Nat Commun 2022 May; 13(1): 2442.
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2022Sensitive visualization of SARS-CoV-2 RNA with CoronaFISH., Life Sci Alliance 2022 04; 5(4): .
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2022Serum neutralization of SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in patients receiving monoclonal antibodies., Nat Med 2022 Mar; (): .
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2022Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2., EBioMedicine 2022 Mar; 77(): 103934.
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2022Considerable escape of SARS-CoV-2 Omicron to antibody neutralization., Nature 2022 02; 602(7898): 671-675.
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2021A novel SARS-CoV-2 related coronavirus in bats from Cambodia., Nat Commun 2021 11; 12(1): 6563.
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2021A live measles-vectored COVID-19 vaccine induces strong immunity and protection from SARS-CoV-2 challenge in mice and hamsters., Nat Commun 2021 11; 12(1): 6277.
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2021Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization., Nature 2021 08; 596(7871): 276-280.
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