Timeline

Etienne Simon-Loriere

Head of Structure

20 Feb 2025

publication

miRNome analysis reveals mir-155-5p as a protective factor to dengue infection in a resistant Thai cohort.

01 Jan 2025

publication

Structural insights into tecovirimat antiviral activity and poxvirus resistance

14 Oct 2024

publication

Genotypic and phenotypic characterisation of respiratory syncytial virus after nirsevimab breakthrough infections: a large, multicentre, observational, real-world study.

19 Jul 2024

publication

Broad sarbecovirus neutralization by combined memory B cell antibodies to ancestral SARS-CoV-2.

10 Apr 2024

event

Adapting to Change: Emerging Infectious Diseases in a Shifting Climate

13 Mar 2024

publication

Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion.

01 Jan 2024

publication

Escape of SARS-CoV-2 Variants KP.1.1, LB.1, and KP3.3 From Approved Monoclonal Antibodies.

13 Dec 2023

publication

High fusion and cytopathy of SARS-CoV-2 variant B.1.640.1.

01 Nov 2023

publication

Untargeted metagenomic sequencing identifies Toscana virus in patients with idiopathic meningitis, southern Spain, 2015 to 2019.

25 Oct 2023

publication

TMPRSS2 is a functional receptor for human coronavirus HKU1.

26 Jul 2023

publication

Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants.

24 May 2023

publication

APOBEC3F is a mutational driver of the human Monkeypox virus identified in the 2022 outbreak.

21 Apr 2023

publication

Enhanced neutralization escape to therapeutic monoclonal antibodies by SARS-CoV-2 omicron sub-lineages.

14 Feb 2023

publication

Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies.

03 Feb 2023

publication

Tocilizumab treated convalescent COVID-19 patients retain the cross-neutralization potential against SARS-CoV-2 variants.

13 Dec 2022

event

PICREID Midterm Meeting Keynote Speaker Event: Novel discoveries in emerging infectious diseases (Kei Sato, Keita Matsuno and Akatsuki Saito)

24 Nov 2022

event

PICREID project Midterm Meeting: Pasteur International Center for Research on Emerging Infectious Diseases

17 Nov 2022

publication

Longitudinal analysis of serum neutralization of SARS-CoV-2 Omicron BA.2, BA.4, and BA.5 in patients receiving monoclonal antibodies.

05 Oct 2022

publication

Duration of BA.5 neutralization in sera and nasal swabs from SARS-CoV-2 vaccinated individuals, with or without omicron breakthrough infection.

04 Jul 2022

publication

Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.

17 Jun 2022

news

New publication – Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2

14 Jun 2022

publication

Analysis of mRNA vaccination-elicited RBD-specific memory B cells reveals strong but incomplete immune escape of the SARS-CoV-2 Omicron variant.

01 Jun 2022

publication

Serum neutralization of SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in patients receiving monoclonal antibodies.

04 May 2022

publication

Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen.

01 Apr 2022

publication

Sensitive visualization of SARS-CoV-2 RNA with CoronaFISH.

01 Apr 2022

publication

Towards SARS-CoV-2 serotypes?

07 Mar 2022

publication

SARS-CoV-2 Omicron emergence urges for reinforced One-Health surveillance.

03 Mar 2022

publication

Antibody escape and global spread of SARS-CoV-2 lineage A.27

01 Mar 2022

publication

Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2.

01 Feb 2022

publication

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization.

01 Feb 2022

publication

A new SARS-CoV-2 variant with high lethality poorly detected by RT-PCR on nasopharyngeal samples: an observational study.

01 Dec 2021

publication

A live measles-vectored COVID-19 vaccine induces strong immunity and protection from SARS-CoV-2 challenge in mice and hamsters.

09 Nov 2021

publication

A novel SARS-CoV-2 related coronavirus in bats from Cambodia.

29 Sep 2021

project

Mouse models for COVID-19

08 Jul 2021

publication

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization.

24 Jun 2021

project

Evolutionary Mechanisms underlying Yellow fever Resurgence in Africa – ANR JCJC

11 Jun 2021

news

COVID-19: sensitivity of the Indian variant (B.1.617.2) to monoclonal antibodies and sera from convalescent and vaccinated individuals

19 May 2021

publication

Lessons learned from the investigation of a COVID-19 cluster in Creil, France: effectiveness of targeting symptomatic cases and conducting contact tracing around them.

10 Feb 2021

publication

Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains.

09 Oct 2020

project

Study of immune crosstalk in COVID-19 COVIMUNE

03 Sep 2020

project

Host genetic susceptibility to Zika virus

03 Aug 2020

program_project

Pasteur International Center for Research on Emerging Infectious Diseases

01 Jul 2020

publication

Introductions and early spread of SARS-CoV-2 in France, 24 January to 23 March 2020.

17 Jan 2020

publication

Genetic Diversity of Collaborative Cross Mice Controls Viral Replication, Clinical Severity, and Brain Pathology Induced by Zika Virus Infection, Independently of Oas1b.

21 Jun 2019

publication

A Modified mRNA Vaccine Targeting Immunodominant NS Epitopes Protects Against Dengue Virus Infection in HLA Class I Transgenic Mice

18 Jun 2019

project

Welcome to the Nanopore User Group at Institut Pasteur webpage

06 Feb 2019

project

MICROTONE – Microbial and viral circulations among people and wild and domesticated animals in an ecotone, Democratic Republic of Congo

08 Oct 2018

patent

A Zika virus chimeric polyepitope comprising non-structural proteins and its use in immunogenic composition (EP 17 306553.3)

10 Jul 2018

publication

RIG-I Recognizes the 5′ Region of Dengue and Zika Virus Genomes.

01 Apr 2018

publication

Genetic Characterization of Enterovirus A71 Circulating in Africa.

15 Feb 2018

publication

Joint ancestry and association test indicate two distinct pathogenic pathways involved in classical dengue fever and dengue shock syndrome

19 Jan 2018

team

Evolutionary genomics of RNA viruses

05 Sep 2017

news

Cover page in Science Translational Medicine

30 Aug 2017

publication

Increased adaptive immune responses and proper feedback regulation protect against clinical dengue.

14 Jun 2017

publication

Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells.

13 Apr 2017

publication

Autochthonous Japanese Encephalitis with Yellow Fever Coinfection in Africa.

12 Apr 2017

publication

Virus genomes reveal factors that spread and sustained the Ebola epidemic

03 Nov 2016

publication

Human Adaptation of Ebola Virus during the West African Outbreak

01 Nov 2016

publication

Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses.

27 Oct 2016

publication

ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53

10 Aug 2016

publication

Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses.

24 Jun 2015

publication

Distinct lineages of Ebola virus in Guinea during the 2014 West African epidemic

10 Jun 2015

publication

High Anti-Dengue Virus Activity of the OAS Gene Family Is Associated With Increased Severity of Dengue

11 May 2015

team

Ecology and Emergence of Arthropod-borne Pathogens

24 Oct 2013

publication

Genetic diversity of the highly variable V1 region interferes with Human Immunodeficiency Virus type 1 envelope functionality

17 May 2013

publication

The effect of gene overlapping on the rate of RNA virus evolution

13 Mar 2013

publication

Gene duplication is infrequent in the recent evolutionary history of RNA viruses

23 Aug 2012

publication

Retrovolution: HIV-driven evolution of cellular genes and improvement of anticancer drug activation

15 Feb 2012

publication

Level of gene expression is a major determinant of protein evolution in the viral order Mononegavirales

04 Jul 2011

publication

Why do RNA viruses recombine?

01 Mar 2011

publication

RNA structures, genomic organization and selection of recombinant HIV

29 Sep 2010

publication

RNA structures facilitate recombination-mediated gene swapping in HIV-1

08 May 2009

publication

Molecular mechanisms of recombination restriction in the envelope gene of the human immunodeficiency virus

12 Sep 2008

publication

Identifying the important HIV-1 recombination breakpoints

04 Mar 2008

publication

Implications of recombination for HIV diversity

26 Sep 2006

publication

A little guide for advanced search:

miRNome analysis reveals mir-155-5p as a protective factor to dengue infection in a resistant Thai cohort.

Structural insights into tecovirimat antiviral activity and poxvirus resistance

Genotypic and phenotypic characterisation of respiratory syncytial virus after nirsevimab breakthrough infections: a large, multicentre, observational, real-world study.

Broad sarbecovirus neutralization by combined memory B cell antibodies to ancestral SARS-CoV-2.

Adapting to Change: Emerging Infectious Diseases in a Shifting Climate

Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion.

Escape of SARS-CoV-2 Variants KP.1.1, LB.1, and KP3.3 From Approved Monoclonal Antibodies.

High fusion and cytopathy of SARS-CoV-2 variant B.1.640.1.

Untargeted metagenomic sequencing identifies Toscana virus in patients with idiopathic meningitis, southern Spain, 2015 to 2019.

TMPRSS2 is a functional receptor for human coronavirus HKU1.

Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants.

APOBEC3F is a mutational driver of the human Monkeypox virus identified in the 2022 outbreak.

Enhanced neutralization escape to therapeutic monoclonal antibodies by SARS-CoV-2 omicron sub-lineages.

Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies.

Tocilizumab treated convalescent COVID-19 patients retain the cross-neutralization potential against SARS-CoV-2 variants.

PICREID Midterm Meeting Keynote Speaker Event: Novel discoveries in emerging infectious diseases (Kei Sato, Keita Matsuno and Akatsuki Saito)

PICREID project Midterm Meeting: Pasteur International Center for Research on Emerging Infectious Diseases

Longitudinal analysis of serum neutralization of SARS-CoV-2 Omicron BA.2, BA.4, and BA.5 in patients receiving monoclonal antibodies.

Duration of BA.5 neutralization in sera and nasal swabs from SARS-CoV-2 vaccinated individuals, with or without omicron breakthrough infection.

Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.

New publication – Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2

Analysis of mRNA vaccination-elicited RBD-specific memory B cells reveals strong but incomplete immune escape of the SARS-CoV-2 Omicron variant.

Serum neutralization of SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in patients receiving monoclonal antibodies.

Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen.

Sensitive visualization of SARS-CoV-2 RNA with CoronaFISH.

Towards SARS-CoV-2 serotypes?

SARS-CoV-2 Omicron emergence urges for reinforced One-Health surveillance.

Antibody escape and global spread of SARS-CoV-2 lineage A.27

Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2.

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization.

A new SARS-CoV-2 variant with high lethality poorly detected by RT-PCR on nasopharyngeal samples: an observational study.

A live measles-vectored COVID-19 vaccine induces strong immunity and protection from SARS-CoV-2 challenge in mice and hamsters.

A novel SARS-CoV-2 related coronavirus in bats from Cambodia.

Mouse models for COVID-19

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization.

Evolutionary Mechanisms underlying Yellow fever Resurgence in Africa – ANR JCJC

COVID-19: sensitivity of the Indian variant (B.1.617.2) to monoclonal antibodies and sera from convalescent and vaccinated individuals

Lessons learned from the investigation of a COVID-19 cluster in Creil, France: effectiveness of targeting symptomatic cases and conducting contact tracing around them.

Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains.

Study of immune crosstalk in COVID-19 COVIMUNE

Host genetic susceptibility to Zika virus

Pasteur International Center for Research on Emerging Infectious Diseases

Introductions and early spread of SARS-CoV-2 in France, 24 January to 23 March 2020.

Genetic Diversity of Collaborative Cross Mice Controls Viral Replication, Clinical Severity, and Brain Pathology Induced by Zika Virus Infection, Independently of Oas1b.

A Modified mRNA Vaccine Targeting Immunodominant NS Epitopes Protects Against Dengue Virus Infection in HLA Class I Transgenic Mice

Welcome to the Nanopore User Group at Institut Pasteur webpage

MICROTONE – Microbial and viral circulations among people and wild and domesticated animals in an ecotone, Democratic Republic of Congo

A Zika virus chimeric polyepitope comprising non-structural proteins and its use in immunogenic composition (EP 17 306553.3)

RIG-I Recognizes the 5′ Region of Dengue and Zika Virus Genomes.

Genetic Characterization of Enterovirus A71 Circulating in Africa.

Joint ancestry and association test indicate two distinct pathogenic pathways involved in classical dengue fever and dengue shock syndrome

Evolutionary genomics of RNA viruses

Cover page in Science Translational Medicine

Increased adaptive immune responses and proper feedback regulation protect against clinical dengue.

Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells.

Autochthonous Japanese Encephalitis with Yellow Fever Coinfection in Africa.

Virus genomes reveal factors that spread and sustained the Ebola epidemic

Human Adaptation of Ebola Virus during the West African Outbreak

Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses.

ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53

Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses.

Distinct lineages of Ebola virus in Guinea during the 2014 West African epidemic

High Anti-Dengue Virus Activity of the OAS Gene Family Is Associated With Increased Severity of Dengue

Ecology and Emergence of Arthropod-borne Pathogens

Genetic diversity of the highly variable V1 region interferes with Human Immunodeficiency Virus type 1 envelope functionality

The effect of gene overlapping on the rate of RNA virus evolution

Gene duplication is infrequent in the recent evolutionary history of RNA viruses

Retrovolution: HIV-driven evolution of cellular genes and improvement of anticancer drug activation

Level of gene expression is a major determinant of protein evolution in the viral order Mononegavirales

Why do RNA viruses recombine?

RNA structures, genomic organization and selection of recombinant HIV

RNA structures facilitate recombination-mediated gene swapping in HIV-1

Molecular mechanisms of recombination restriction in the envelope gene of the human immunodeficiency virus

Identifying the important HIV-1 recombination breakpoints

Implications of recombination for HIV diversity

Sequence determinants of breakpoint location during HIV-1 intersubtype recombination