300 to 400 million cases of dengue fever occur each year worldwide. Spreading rapidly, more than 40% of the world’s population is now at risk of contracting dengue This transversal program brings together talents […]
LabEx Milieu Intérieur
The Milieu Intérieur project provides insight into the core of human diversity by dissecting the interplay between genetics and environment and their impact on the immune system. https://www.youtube.com/watch?v=IXlKElDJMc8 The Milieu Intérieur Project While the […]
LabEx IBEID – Integrative Biology of Emerging Infectious Diseases
Presentation The aim of the Integrative Biology of Emerging Infectious Diseases (IBEID) project, coordinated by Professors Philippe Sansonetti and Pascale Cossart, is to develop a structure to anticipate and tackle emerging infectious diseases (EIDs). […]
Study of immune crosstalk in COVID-19 COVIMUNE
Our overall goal is to understand the cellular and molecular aspects of immune response to SARS-CoV-2 virus in terms of activation of over-reactive immunity and induction of immune protection. COVIMUNE is designed to target […]
Host genetic susceptibility to Zika virus
Zika virus is an arbovirus responsible for recent epidemics in Polynesia and in the Americas. Clinical descriptions range from mild flu-like syndromes to rare but severe neurological complications such as Guillain-Barré syndrome and encephalitis […]
Pasteur International Center for Research on Emerging Infectious Diseases
We established an Emerging Infectious Disease Research Center in Southeast Asia and West/Central Africa with an inter-continental one-health approach designed to improve the capacity to respond rapidly and effectively to outbreaks. We built on […]
Protected: Pasteur Human Genome
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Effect of host-parasite interaction on the outcome of malaria infection
It is well accepted that the outcome of infection in malaria depends upon interaction between the human host and Plasmodium spp. This is the result of forces of selection and escape acting on the […]
DENFREE consortium – Dengue Framework for Resisting Epidemics in Europe
The main objective of the programme is to focus on finding key factors determining dengue transmission and dynamics in order to develop new tools and strategies for controlling dengue transmission. We will estimate the […]
CoSimmGen : Constitution of a prospective cohort of healthy and diseased individuals with an associated human biological resources collection for the purpose of studying of genetic, immunological and environmental factors in human diseases
Context : Studying physiopathology of human diseases, focused in particular on genetic, immunological and environmental factors necessitate to access to human cohorts of healthy and diseased individuals and the corresponding bioresources. The rarity of […]
A Zika virus chimeric polyepitope comprising non-structural proteins and its use in immunogenic composition (EP 17 306553.3)
The present invention is directed to a Zika virus (ZIKV) chimeric polyepitope composed of fragments of structural and non-structural proteins and its use in an immunogenic composition. The present invention provides means, in particular […]
A dengue virus chimeric polyepitope composed of fragments of non-structural proteins and its use in an immunogenic composition against dengue virus infection (E14305984.8)
The present invention is directed to a dengue virus chimeric polyepitope composed of fragments of non-structural proteins and its use in an immunogenic composition against dengue virus infection. The present invention provides means, in […]
2022SKAP2 modular organization differently recognizes SRC kinases depending on their activation status and localization., Mol Cell Proteomics 2022 Nov; (): 100451.
2022Yearly variations of the genetic structure of Aedes aegypti (Linnaeus) (Diptera: Culicidae) in the Philippines (2017-2019)., Infect Genet Evol 2022 08; 102(): 105296.
2022Dengue virus NS1 protein conveys pro-inflammatory signals by docking onto high-density lipoproteins., EMBO Rep 2022 May; (): e53600.
2022Single-cell temporal analysis of natural dengue infection reveals skin-homing lymphocyte expansion one day before defervescence., iScience 2022 Apr; 25(4): 104034.
2022Novel and Broadly Applicable Microsatellite Markers in Identified Chromosomes of the Philippine Dengue Mosquitoes, Aedes aegypti (Diptera: Culicidae)., J Med Entomol 2022 03; 59(2): 545-553.
2022Temperature, season, and latitude influence development-related phenotypes of Philippine Aedes aegypti (Linnaeus): Implications for dengue control amidst global warming., Parasit Vectors 2022 Mar; 15(1): 74.
2022SARS-CoV-2 Induces Cytokine Responses in Human Basophils., Front Immunol 2022 ; 13(): 838448.
2021Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths., Sci Immunol 2021 08; 6(62): .
2021Antibody fucosylation predicts disease severity in secondary dengue infection., Science 2021 06; 372(6546): 1102-1105.
2021Dengue Virus Serotype 2 Intrahost Diversity in Patients with Different Clinical Outcomes., Viruses 2021 02; 13(2): .
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