Timeline
Laurent Debarbieux
Head of Structure
01 Nov 2024
publication
Prediction of strain level phage-host interactions across the Escherichia genus using only genomic information.
Read more24 Oct 2024
07 Oct 2024
event
Seminar Dept Microbiology “Developing phage therapy against antimicrobial resistant bacterial infections.”
Read more26 Sep 2024
publication
Biophysical insights into sugar-dependent medium acidification promoting YfaL protein-mediated Escherichia coli self-aggregation, biofilm formation and acid stress resistance.
Read more04 Sep 2024
publication
Stable coexistence between an archaeal virus and the dominant methanogen of the human gut.
Read more04 Sep 2024
publication
Metapopulation model of phage therapy of an acute Pseudomonas aeruginosa lung infection.
Read more30 Aug 2024
publication
Variable fitness effects of bacteriophage resistance mutations in Escherichia coli: implications for phage therapy.
Read more15 Jul 2024
publication
Improving the intestinal lipidome coverage in a gnotobiotic mouse model using UHPLC-MS-based approach through optimization of mobile phase modifiers and column selection.
Read more10 Jul 2024
project
Identification de marqueurs sanguins permettant d’évaluer la toxicité de bactériophages : PHAGESAFETY
Read more12 Mar 2024
publication
Complete genome sequences of two Klebsiella pneumoniae phages from Dakar, Senegal.
Read more19 Feb 2024
publication
High-Throughput Bacteriophage Testing with Potency Determination: Validation of an Automated Pipetting and Phage Drop-Off Method.
Read more01 Jan 2024
publication
A nanoluciferase-encoded bacteriophage illuminates viral infection dynamics of Pseudomonas aeruginosa cells.
Read more24 Aug 2023
event
Dept Microbiology & Global Health joint Seminar | Stephen Baker “Where do we go next with AMR?”
Read more12 Aug 2023
publication
Human Neutrophil Response to Pseudomonas Bacteriophage PAK_P1, a Therapeutic Candidate.
Read more01 Aug 2023
publication
Bacteriophages targeting protective commensals impair resistance against Salmonella Typhimurium infection in gnotobiotic mice.
Read more19 May 2023
publication
Chromosome folding and prophage activation reveal specific genomic architecture for intestinal bacteria.
Read more10 Dec 2022
publication
The role of the animal host in the management of bacteriophage resistance during phage therapy.
Read more26 Oct 2022
publication
The Selection of Antibiotic- and Bacteriophage-Resistant Pseudomonas aeruginosa Is Prevented by Their Combination.
Read more17 May 2022
publication
Combination of in vivo phage therapy data with in silico model highlights key parameters for pneumonia treatment efficacy.
Read more15 Apr 2022
news
A recent study by the team of Laurent Debarbieux has been highlighted in the BIP (15/04/2022)
Read more13 Apr 2022
publication
The gut environment regulates bacterial gene expression which modulates susceptibility to bacteriophage infection.
Read more25 Jan 2022
news
Congratulation to Laurent Debarbieux for leading the new research unit entitled Bacteriophage, Bacterium, Host.
Read more17 Nov 2021
news
“Bacteriophages, à table” on France Culture radio, Monday 15th, November with Laurent Debardieux
Read more23 Oct 2021
20 Oct 2021
03 Sep 2021
publication
Prophylactic Administration of a Bacteriophage Cocktail Is Safe and Effective in Reducing Salmonella enterica Serovar Typhimurium Burden in Vivo.
Read more29 Apr 2021
publication
Closed and High-Quality Bacterial Genome Sequences of the Oligo-Mouse-Microbiota Community.
Read more17 Feb 2021
publication
Viral Host Range database, an online tool for recording, analyzing and disseminating virus-host interactions.
Read more28 Oct 2020
event
Seminar DPT Microbiology – “Bacteriophage; providing context for the microbiome”, Prof. Colin HILL
Read more09 Sep 2020
publication
The Spatial Heterogeneity of the Gut Limits Predation and Fosters Coexistence of Bacteria and Bacteriophages.
Read more21 Aug 2020
publication
Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage.
Read more08 Jul 2020
publication
Isolation and Characterization of Bacteriophages That Infect Citrobacter rodentium, a Model Pathogen for Intestinal Diseases
Read more12 Jun 2020
12 Jun 2020
publication
Optimizing the Timing and Composition of Therapeutic Phage Cocktails: A Control-Theoretic Approach.
Read more01 Mar 2020
publication
Circulating neutrophil and eosinophil extracellular traps are markers of severe asthma.
Read more04 Feb 2020
01 Feb 2020
01 Feb 2020
01 Nov 2019
publication
[Pseudomonas aeruginosa uses its filamentous bacteriophages to manipulate the immune system].
Read more25 Jul 2019
publication
Phage Therapy of Pneumonia Is Not Associated with an Overstimulation of the Inflammatory Response Compared to Antibiotic Treatment in Mice
Read more12 Apr 2019
event
Thesis defense – Marta MANSOS LOURENCO : Deciphering in vivo efficacy of virulent phages in the mammalian gut.
Read more13 Feb 2019
publication
The Battle Within: Interactions of Bacteriophages and Bacteria in the Gastrointestinal Tract
Read more02 Nov 2018
10 Sep 2018
15 Jun 2018
25 May 2018
publication
Design of a Broad-Range Bacteriophage Cocktail That Reduces Pseudomonas aeruginosa Biofilms and Treats Acute Infections in Two Animal Models
Read more05 Apr 2018
publication
Expert Opinion on Three Phage Therapy Related Topics: Bacterial Phage Resistance, Phage Training and Prophages in Bacterial Production Strains.
Read more01 Apr 2018
16 Nov 2017
publication
The Gut Microbiota Facilitates Drifts in the Genetic Diversity and Infectivity of Bacterial Viruses
Read more12 Jul 2017
publication
Synergy between the Host Immune System and Bacteriophage Is Essential for Successful Phage Therapy against an Acute Respiratory Pathogen
Read more01 Jun 2017
publication
The Lysis of Pathogenic Escherichia coli by Bacteriophages Releases Less Endotoxin Than by β-Lactams
Read more12 May 2017
publication
Comparative transcriptomics analyses reveal the conservation of an ancestral infectious strategy in two bacteriophage genera
Read more13 Apr 2017
event
“Comprehensive study of new virulent bacteriophages: From transcriptomic and mechanistic characterisations towards evolutionary perspectives” by Anne CHEVALLEREAU
Read more06 Apr 2017
01 Apr 2017
27 Jan 2017
publication
Bacteriophages targeting adherent invasive Escherichia coli strains as a promising new treatment for Crohn’s disease
Read more03 Oct 2016
07 Jul 2016
publication
Bacteriophage LM33_P1, a fast-acting weapon against the pandemic ST131-O25b:H4 Escherichia coli clonal complex
Read more05 Jul 2016
publication
Next-Generation “-omics” Approaches Reveal a Massive Alteration of Host RNA Metabolism during Bacteriophage Infection of Pseudomonas aeruginosa
Read more28 Jun 2016
publication
Commentary: Morphologically Distinct Escherichia coli Bacteriophages Differ in Their Efficacy and Ability to Stimulate Cytokine Release In Vitro
Read more11 Mar 2016
publication
Bacteriophages to reduce gut carriage of antibiotic resistant uropathogens with low impact on microbiota composition
Read more01 Jan 2016
15 Sep 2015
03 Sep 2015
03 Sep 2015
22 Jul 2015
20 Jul 2015
20 Jul 2015
16 Jul 2015
01 Jun 2015
publication
Treatment of Highly Virulent Extraintestinal Pathogenic Escherichia coli Pneumonia With Bacteriophages
Read more28 Jan 2015
publication
The search for therapeutic bacteriophages uncovers one new subfamily and two new genera of Pseudomonas-infecting Myoviridae
Read more14 Jan 2015
26 Jul 2014
19 Jun 2014
publication
Bacterial sensing of bacteriophages in communities: the search for the Rosetta stone
Read more13 Dec 2013
16 Sep 2013
publication
Predicting in vivo efficacy of therapeutic bacteriophages used to treat pulmonary infections
Read more06 Jun 2013
publication
Enterococcus faecalis prophage dynamics and contributions to pathogenic traits
Read more11 Apr 2013
publication
Key issues in phage therapy: a report of a dedicated workshop at the Viruses of Microbes II meeting
Read more07 Mar 2013
publication
Characterization of nasal potential difference in cftr knockout and F508del-CFTR mice
Read more07 Dec 2012
publication
Meeting report of the European Molecular Biology Organization (EMBO) Symposium ‘Viruses of Microbes II’, Brussels, July 2012
Read more12 Oct 2012
01 Oct 2012
24 Sep 2012
publication
Virulent bacteriophages can target O104:H4 enteroaggregative Escherichia coli in the mouse intestine
Read more01 Jan 2012
publication
Bacteriophages in the experimental treatment of Pseudomonas aeruginosa infections in mice
Read more28 Nov 2011
publication
Intestinal colonization by enteroaggregative Escherichia coli supports long-term bacteriophage replication in mice
Read more29 Mar 2011
publication
Bacteriophages as twenty-first century antibacterial tools for food and medicine
Read more15 Feb 2011
publication
Pulmonary bacteriophage therapy on Pseudomonas aeruginosa cystic fibrosis strains: first steps towards treatment and prevention
Read more10 Nov 2010
01 Apr 2010
09 Aug 2008
08 Aug 2008
08 Dec 2006
publication
Probing the in vivo dynamics of type I protein secretion complex association through sensitivity to detergents
Read more15 Dec 2005
publication
A selection for mutants that interfere with folding of Escherichia coli thioredoxin-1 in vivo
Read more01 Oct 2003
publication
Ligand delivery by haem carrier proteins: the binding of Serratia marcescens haemophore to its outer membrane receptor is mediated by two distinct peptide regions
Read more01 Sep 2001
01 Feb 2000
publication
On the functional interchangeability, oxidant versus reductant, of members of the thioredoxin superfamily
Read more15 Oct 1999
01 Sep 1998
publication
The reductive enzyme thioredoxin 1 acts as an oxidant when it is exported to the Escherichia coli periplasm
Read more01 Nov 1997
publication
Topological analysis of the membrane-bound glucosyltransferase, MdoH, required for osmoregulated periplasmic glucan synthesis in Escherichia coli
Read more01 Oct 1993
publication