Ligne de temps
Laurent Debarbieux
Responsable de Structure
26 sept. 2024
publication
Biophysical insights into sugar-dependent medium acidification promoting YfaL protein-mediated Escherichia coli self-aggregation, biofilm formation and acid stress resistance.
Lire plus04 sept. 2024
publication
Stable coexistence between an archaeal virus and the dominant methanogen of the human gut
Lire plus04 sept. 2024
publication
Metapopulation model of phage therapy of an acute Pseudomonas aeruginosa lung infection.
Lire plus30 août 2024
publication
Variable fitness effects of bacteriophage resistance mutations in Escherichia coli: implications for phage therapy.
Lire plus15 juil. 2024
publication
Improving the intestinal lipidome coverage in a gnotobiotic mouse model using UHPLC-MS-based approach through optimization of mobile phase modifiers and column selection.
Lire plus10 juil. 2024
project
Identification de marqueurs sanguins permettant d’évaluer la toxicité de bactériophages : PHAGESAFETY (2023-001)
Lire plus12 mars 2024
publication
Complete genome sequences of two Klebsiella pneumoniae phages from Dakar, Senegal.
Lire plus19 févr. 2024
publication
High-Throughput Bacteriophage Testing with Potency Determination: Validation of an Automated Pipetting and Phage Drop-Off Method.
Lire plus01 janv. 2024
publication
A nanoluciferase-encoded bacteriophage illuminates viral infection dynamics of Pseudomonas aeruginosa cells.
Lire plus24 août 2023
event
Dept Microbiology & Global Health joint Seminar | Stephen Baker “Where do we go next with AMR?”
Lire plus12 août 2023
publication
Human Neutrophil Response to Pseudomonas Bacteriophage PAK_P1, a Therapeutic Candidate.
Lire plus01 août 2023
publication
Bacteriophages targeting protective commensals impair resistance against Salmonella Typhimurium infection in gnotobiotic mice.
Lire plus19 mai 2023
publication
Chromosome folding and prophage activation reveal specific genomic architecture for intestinal bacteria.
Lire plus10 déc. 2022
publication
The role of the animal host in the management of bacteriophage resistance during phage therapy.
Lire plus26 oct. 2022
publication
The Selection of Antibiotic- and Bacteriophage-Resistant Pseudomonas aeruginosa Is Prevented by Their Combination.
Lire plus17 mai 2022
publication
Combination of in vivo phage therapy data with in silico model highlights key parameters for pneumonia treatment efficacy.
Lire plus15 avr. 2022
news
A recent study by the team of Laurent Debarbieux has been highlighted in the BIP (15/04/2022)
Lire plus13 avr. 2022
publication
The gut environment regulates bacterial gene expression which modulates susceptibility to bacteriophage infection.
Lire plus25 janv. 2022
news
Congratulation to Laurent Debarbieux for leading the new research unit entitled Bacteriophage, Bacterium, Host.
Lire plus17 nov. 2021
news
“Bacteriophages, à table” on France Culture radio, Monday 15th, November with Laurent Debardieux
Lire plus23 oct. 2021
20 oct. 2021
03 sept. 2021
publication
Prophylactic Administration of a Bacteriophage Cocktail Is Safe and Effective in Reducing Salmonella enterica Serovar Typhimurium Burden in Vivo.
Lire plus29 avr. 2021
publication
Closed and High-Quality Bacterial Genome Sequences of the Oligo-Mouse-Microbiota Community.
Lire plus17 févr. 2021
publication
Viral Host Range database, an online tool for recording, analyzing and disseminating virus-host interactions.
Lire plus28 oct. 2020
event
Seminar DPT Microbiology – “Bacteriophage; providing context for the microbiome”, Prof. Colin HILL
Lire plus09 sept. 2020
publication
The Spatial Heterogeneity of the Gut Limits Predation and Fosters Coexistence of Bacteria and Bacteriophages.
Lire plus21 août 2020
publication
Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage.
Lire plus08 juil. 2020
publication
Isolation and Characterization of Bacteriophages That Infect Citrobacter rodentium, a Model Pathogen for Intestinal Diseases
Lire plus12 juin 2020
12 juin 2020
publication
Optimizing the Timing and Composition of Therapeutic Phage Cocktails: A Control-Theoretic Approach.
Lire plus01 mars 2020
publication
Circulating neutrophil and eosinophil extracellular traps are markers of severe asthma.
Lire plus04 févr. 2020
01 févr. 2020
01 févr. 2020
01 nov. 2019
publication
[Pseudomonas aeruginosa uses its filamentous bacteriophages to manipulate the immune system].
Lire plus25 juil. 2019
publication
Phage Therapy of Pneumonia Is Not Associated with an Overstimulation of the Inflammatory Response Compared to Antibiotic Treatment in Mice
Lire plus12 avr. 2019
event
Thesis defense – Marta MANSOS LOURENCO : Deciphering in vivo efficacy of virulent phages in the mammalian gut.
Lire plus13 févr. 2019
publication
The Battle Within: Interactions of Bacteriophages and Bacteria in the Gastrointestinal Tract
Lire plus02 nov. 2018
10 sept. 2018
15 juin 2018
25 mai 2018
publication
Design of a Broad-Range Bacteriophage Cocktail That Reduces Pseudomonas aeruginosa Biofilms and Treats Acute Infections in Two Animal Models
Lire plus05 avr. 2018
publication
Expert Opinion on Three Phage Therapy Related Topics: Bacterial Phage Resistance, Phage Training and Prophages in Bacterial Production Strains.
Lire plus01 avr. 2018
16 nov. 2017
publication
The Gut Microbiota Facilitates Drifts in the Genetic Diversity and Infectivity of Bacterial Viruses
Lire plus12 juil. 2017
publication
Synergy between the Host Immune System and Bacteriophage Is Essential for Successful Phage Therapy against an Acute Respiratory Pathogen
Lire plus01 juin 2017
publication
The Lysis of Pathogenic Escherichia coli by Bacteriophages Releases Less Endotoxin Than by β-Lactams
Lire plus12 mai 2017
publication
Comparative transcriptomics analyses reveal the conservation of an ancestral infectious strategy in two bacteriophage genera
Lire plus13 avr. 2017
event
“Comprehensive study of new virulent bacteriophages: From transcriptomic and mechanistic characterisations towards evolutionary perspectives” by Anne CHEVALLEREAU
Lire plus06 avr. 2017
01 avr. 2017
27 janv. 2017
publication
Bacteriophages targeting adherent invasive Escherichia coli strains as a promising new treatment for Crohn’s disease
Lire plus03 oct. 2016
07 juil. 2016
publication
Bacteriophage LM33_P1, a fast-acting weapon against the pandemic ST131-O25b:H4 Escherichia coli clonal complex
Lire plus05 juil. 2016
publication
Next-Generation “-omics” Approaches Reveal a Massive Alteration of Host RNA Metabolism during Bacteriophage Infection of Pseudomonas aeruginosa
Lire plus28 juin 2016
publication
Commentary: Morphologically Distinct Escherichia coli Bacteriophages Differ in Their Efficacy and Ability to Stimulate Cytokine Release In Vitro
Lire plus11 mars 2016
publication
Bacteriophages to reduce gut carriage of antibiotic resistant uropathogens with low impact on microbiota composition
Lire plus01 janv. 2016
15 sept. 2015
03 sept. 2015
03 sept. 2015
22 juil. 2015
20 juil. 2015
20 juil. 2015
16 juil. 2015
01 juin 2015
publication
Treatment of Highly Virulent Extraintestinal Pathogenic Escherichia coli Pneumonia With Bacteriophages
Lire plus28 janv. 2015
publication
The search for therapeutic bacteriophages uncovers one new subfamily and two new genera of Pseudomonas-infecting Myoviridae
Lire plus14 janv. 2015
26 juil. 2014
19 juin 2014
publication
Bacterial sensing of bacteriophages in communities: the search for the Rosetta stone
Lire plus13 déc. 2013
16 sept. 2013
publication
Predicting in vivo efficacy of therapeutic bacteriophages used to treat pulmonary infections
Lire plus06 juin 2013
publication
Enterococcus faecalis prophage dynamics and contributions to pathogenic traits
Lire plus11 avr. 2013
publication
Key issues in phage therapy: a report of a dedicated workshop at the Viruses of Microbes II meeting
Lire plus07 mars 2013
publication
Characterization of nasal potential difference in cftr knockout and F508del-CFTR mice
Lire plus07 déc. 2012
publication
Meeting report of the European Molecular Biology Organization (EMBO) Symposium ‘Viruses of Microbes II’, Brussels, July 2012
Lire plus12 oct. 2012
01 oct. 2012
24 sept. 2012
publication
Virulent bacteriophages can target O104:H4 enteroaggregative Escherichia coli in the mouse intestine
Lire plus01 janv. 2012
publication
Bacteriophages in the experimental treatment of Pseudomonas aeruginosa infections in mice
Lire plus28 nov. 2011
publication
Intestinal colonization by enteroaggregative Escherichia coli supports long-term bacteriophage replication in mice
Lire plus29 mars 2011
publication
Bacteriophages as twenty-first century antibacterial tools for food and medicine
Lire plus15 févr. 2011
publication
Pulmonary bacteriophage therapy on Pseudomonas aeruginosa cystic fibrosis strains: first steps towards treatment and prevention
Lire plus10 nov. 2010
01 avr. 2010
09 août 2008
08 août 2008
08 déc. 2006
publication
Probing the in vivo dynamics of type I protein secretion complex association through sensitivity to detergents
Lire plus15 déc. 2005
publication
A selection for mutants that interfere with folding of Escherichia coli thioredoxin-1 in vivo
Lire plus01 oct. 2003
publication
Ligand delivery by haem carrier proteins: the binding of Serratia marcescens haemophore to its outer membrane receptor is mediated by two distinct peptide regions
Lire plus01 sept. 2001
01 févr. 2000
publication
On the functional interchangeability, oxidant versus reductant, of members of the thioredoxin superfamily
Lire plus15 oct. 1999
01 sept. 1998
publication
The reductive enzyme thioredoxin 1 acts as an oxidant when it is exported to the Escherichia coli periplasm
Lire plus01 nov. 1997
publication
Topological analysis of the membrane-bound glucosyltransferase, MdoH, required for osmoregulated periplasmic glucan synthesis in Escherichia coli
Lire plus01 oct. 1993
publication