Ligne de temps

Laurent Debarbieux
Responsable de Structure
24 août 2023
event

Dept Microbiology & Global Health joint Seminar | Stephen Baker “Where do we go next with AMR?”

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12 août 2023
publication

Human Neutrophil Response to Pseudomonas Bacteriophage PAK_P1, a Therapeutic Candidate.

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01 août 2023
publication

Bacteriophages targeting protective commensals impair resistance against Salmonella Typhimurium infection in gnotobiotic mice.

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19 mai 2023
publication

Chromosome folding and prophage activation reveal specific genomic architecture for intestinal bacteria.

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10 déc. 2022
publication

The role of the animal host in the management of bacteriophage resistance during phage therapy.

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26 oct. 2022
publication

The Selection of Antibiotic- and Bacteriophage-Resistant Pseudomonas aeruginosa Is Prevented by Their Combination.

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17 mai 2022
publication

Combination of in vivo phage therapy data with in silico model highlights key parameters for pneumonia treatment efficacy.

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15 avr. 2022
news

A recent study by the team of Laurent Debarbieux has been highlighted in the BIP (15/04/2022)

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13 avr. 2022
publication

The gut environment regulates bacterial gene expression which modulates susceptibility to bacteriophage infection.

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25 janv. 2022
news

Congratulation to Laurent Debarbieux for leading the new research unit entitled Bacteriophage, Bacterium, Host.

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17 nov. 2021
news

“Bacteriophages, à table” on France Culture radio, Monday 15th, November with Laurent Debardieux

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23 oct. 2021
publication

The intestinal virome: lessons from animal models.

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20 oct. 2021
publication

Intestinal Bacteriophage Therapy: Looking for Optimal Efficacy.

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03 sept. 2021
publication

Prophylactic Administration of a Bacteriophage Cocktail Is Safe and Effective in Reducing Salmonella enterica Serovar Typhimurium Burden in Vivo.

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29 avr. 2021
publication

Closed and High-Quality Bacterial Genome Sequences of the Oligo-Mouse-Microbiota Community.

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17 févr. 2021
publication

Viral Host Range database, an online tool for recording, analyzing and disseminating virus-host interactions.

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28 oct. 2020
event

Seminar DPT Microbiology – “Bacteriophage; providing context for the microbiome”, Prof. Colin HILL

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09 sept. 2020
publication

The Spatial Heterogeneity of the Gut Limits Predation and Fosters Coexistence of Bacteria and Bacteriophages.

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21 août 2020
publication

Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage.

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08 juil. 2020
publication

Isolation and Characterization of Bacteriophages That Infect Citrobacter rodentium, a Model Pathogen for Intestinal Diseases

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12 juin 2020
publication

In Vivo Bacteriophage Biodistribution.

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12 juin 2020
publication

Optimizing the Timing and Composition of Therapeutic Phage Cocktails: A Control-Theoretic Approach.

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01 mars 2020
publication

Circulating neutrophil and eosinophil extracellular traps are markers of severe asthma.

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04 févr. 2020
project

Viral Host Range database

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01 févr. 2020
publication

A century of research on bacteriophages.

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01 févr. 2020
publication

Antibacterial applications of bacteriophages.

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01 nov. 2019
publication

[Pseudomonas aeruginosa uses its filamentous bacteriophages to manipulate the immune system].

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25 juil. 2019
publication

Phage Therapy of Pneumonia Is Not Associated with an Overstimulation of the Inflammatory Response Compared to Antibiotic Treatment in Mice

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12 avr. 2019
event

Thesis defense – Marta MANSOS LOURENCO : Deciphering in vivo efficacy of virulent phages in the mammalian gut.

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13 févr. 2019
publication

The Battle Within: Interactions of Bacteriophages and Bacteria in the Gastrointestinal Tract

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02 nov. 2018
publication

Centennial celebration of the bacteriophage research

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10 sept. 2018
publication

“I will survive”: A tale of bacteriophage-bacteria coevolution in the gut

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15 juin 2018
publication

The Diversity of Bacterial Lifestyles Hampers Bacteriophage Tenacity

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25 mai 2018
publication

Design of a Broad-Range Bacteriophage Cocktail That Reduces Pseudomonas aeruginosa Biofilms and Treats Acute Infections in Two Animal Models

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05 avr. 2018
publication

Expert Opinion on Three Phage Therapy Related Topics: Bacterial Phage Resistance, Phage Training and Prophages in Bacterial Production Strains.

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01 avr. 2018
publication

[Immunophage synergy is required for successful pulmonary phage therapy].

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16 nov. 2017
publication

The Gut Microbiota Facilitates Drifts in the Genetic Diversity and Infectivity of Bacterial Viruses

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12 juil. 2017
publication

Synergy between the Host Immune System and Bacteriophage Is Essential for Successful Phage Therapy against an Acute Respiratory Pathogen

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01 juin 2017
publication

The Lysis of Pathogenic Escherichia coli by Bacteriophages Releases Less Endotoxin Than by β-Lactams

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12 mai 2017
publication

Comparative transcriptomics analyses reveal the conservation of an ancestral infectious strategy in two bacteriophage genera

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13 avr. 2017
event

“Comprehensive study of new virulent bacteriophages: From transcriptomic and mechanistic characterisations towards evolutionary perspectives” by Anne CHEVALLEREAU

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06 avr. 2017
event

Centennial Celebration of Bacteriophage Research

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01 avr. 2017
publication

[Phage therapy: a realistic weapon against multidrug resistant bacteria].

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27 janv. 2017
publication

Bacteriophages targeting adherent invasive Escherichia coli strains as a promising new treatment for Crohn’s disease

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03 oct. 2016
project

Bacteriophage gene expression by RNA-Seq

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07 juil. 2016
publication

Bacteriophage LM33_P1, a fast-acting weapon against the pandemic ST131-O25b:H4 Escherichia coli clonal complex

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05 juil. 2016
publication

Next-Generation “-omics” Approaches Reveal a Massive Alteration of Host RNA Metabolism during Bacteriophage Infection of Pseudomonas aeruginosa

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28 juin 2016
publication

Commentary: Morphologically Distinct Escherichia coli Bacteriophages Differ in Their Efficacy and Ability to Stimulate Cytokine Release In Vitro

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11 mars 2016
publication

Bacteriophages to reduce gut carriage of antibiotic resistant uropathogens with low impact on microbiota composition

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01 janv. 2016
publication

A bacteriophage journey at the European Medicines Agency.

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15 sept. 2015
project

Molecular characterization of therapeutic bacteriophages

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03 sept. 2015
project

Treatment of pulmonary infections

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03 sept. 2015
project

Virulents bacteriophages and microbial ecosystems

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22 juil. 2015
project

De novo assembly for integration into MicroScope/MaGe platform

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20 juil. 2015
project

16S rDNA data analysis

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20 juil. 2015
project

Variant detection on NGS data

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16 juil. 2015
team

Bactériophage, bactérie, hôte

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01 juin 2015
publication

Treatment of Highly Virulent Extraintestinal Pathogenic Escherichia coli Pneumonia With Bacteriophages

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28 janv. 2015
publication

The search for therapeutic bacteriophages uncovers one new subfamily and two new genera of Pseudomonas-infecting Myoviridae

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14 janv. 2015
publication

Quality and safety requirements for sustainable phage therapy products

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26 juil. 2014
publication

Effectiveness of bacteriophages in the sputum of cystic fibrosis patients

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19 juin 2014
publication

Bacterial sensing of bacteriophages in communities: the search for the Rosetta stone

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13 déc. 2013
publication

[Phagotherapy: a nightmare for bacteria, a dream for physicians?]

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16 sept. 2013
publication

Predicting in vivo efficacy of therapeutic bacteriophages used to treat pulmonary infections

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06 juin 2013
publication

Enterococcus faecalis prophage dynamics and contributions to pathogenic traits

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11 avr. 2013
publication

Key issues in phage therapy: a report of a dedicated workshop at the Viruses of Microbes II meeting

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07 mars 2013
publication

Characterization of nasal potential difference in cftr knockout and F508del-CFTR mice

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07 déc. 2012
publication

Meeting report of the European Molecular Biology Organization (EMBO) Symposium ‘Viruses of Microbes II’, Brussels, July 2012

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12 oct. 2012
publication

Tools from viruses: bacteriophage successes and beyond

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01 oct. 2012
publication

On the interactions between virulent bacteriophages and bacteria in the gut

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24 sept. 2012
publication

Virulent bacteriophages can target O104:H4 enteroaggregative Escherichia coli in the mouse intestine

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01 janv. 2012
publication

Bacteriophages in the experimental treatment of Pseudomonas aeruginosa infections in mice

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28 nov. 2011
publication

Intestinal colonization by enteroaggregative Escherichia coli supports long-term bacteriophage replication in mice

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29 mars 2011
publication

Bacteriophages as twenty-first century antibacterial tools for food and medicine

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15 févr. 2011
publication

Pulmonary bacteriophage therapy on Pseudomonas aeruginosa cystic fibrosis strains: first steps towards treatment and prevention

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10 nov. 2010
publication

The phage therapy paradigm: prêt-à-porter or sur-mesure?

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01 avr. 2010
publication

Bacteriophages can treat and prevent Pseudomonas aeruginosa lung infections

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09 août 2008
publication

[Experimental phage therapy in the beginning of the 21st century]

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08 août 2008
publication

[Organizers’ report]

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08 déc. 2006
publication

Probing the in vivo dynamics of type I protein secretion complex association through sensitivity to detergents

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15 déc. 2005
publication

A selection for mutants that interfere with folding of Escherichia coli thioredoxin-1 in vivo

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01 oct. 2003
publication

Ligand delivery by haem carrier proteins: the binding of Serratia marcescens haemophore to its outer membrane receptor is mediated by two distinct peptide regions

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01 sept. 2001
publication

Folded HasA inhibits its own secretion through its ABC exporter

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01 févr. 2000
publication

On the functional interchangeability, oxidant versus reductant, of members of the thioredoxin superfamily

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15 oct. 1999
publication

Electron avenue: pathways of disulfide bond formation and isomerization

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01 sept. 1998
publication

The reductive enzyme thioredoxin 1 acts as an oxidant when it is exported to the Escherichia coli periplasm

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01 nov. 1997
publication

Topological analysis of the membrane-bound glucosyltransferase, MdoH, required for osmoregulated periplasmic glucan synthesis in Escherichia coli

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01 oct. 1993
publication

Homology between a genetic locus (mdoA) involved in the osmoregulated biosynthesis of periplasmic glucans in Escherichia coli and a genetic locus (hrpM) controlling pathogenicity of Pseudomonas syringae

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