Analysis of T cell responses directed against the spike and/or membrane and/or nucleocapsid proteins in chilblain-like lesions patients during the COVID-19 pandemic.

Lien vers Pubmed [PMID] – 34258762

Lien DOI – 10.1111/bjd.20647

Br J Dermatol 2021 Jul; ():

A range of cutaneous manifestations has been described in association with severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection during the coronavirus disease 2019 (COVID-19) pandemic 1 . Among them, chilblain like lesions (CLL) occurred more frequently than expected. A direct link was demonstrated thanks to the visualization of viral particles in the skin endothelial cells by electron microscopy 2 which was further questioned 3 . An indirect link was highlighted with high prevalence of seropositivity in CLL patients compared to general population 4 .