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Nov 2017
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Présentation

The Group for AIDS Research (Groupe de Réflexion SIDA, GRS) organizes  bimonthly meetings and seminars around an HIV / AIDS research topic.

Meetings and seminars are open to all. Meetings are usually held on Tuesdays at 4 p.m. in room 14 of the Lwoff building, Pasteur Institute, Paris.

The GRS meetings and seminars are organized with the support of ANRS.

The next GRS meeting, to be held on Tuesday November 21,  2017, and will focus on HIV vaccination strategies.   The meeting will be held at 4 PM in room 14 at the first floor of the Lwoff building. Speakers will include :

Frédéric TANGY
Unité de Génomique Virale et Vaccination, Institut Pasteur, Paris
Protective efficacy of live measles-HIV vaccine against SHIV-SF162P3 challenges in cynomolgus macaques 
 
Stéphane PAUL    

Groupe d’Immunité des Muqueuses et Agents Pathogènes/EA3064, INSERM CIE3 1408 Vaccinology, Université de Lyon, Saint-Etienne
Use of SIgA for HIV mucosal vaccination    

 
Pierre CHARNEAU

Unité de Virologie Moléculaire et Vaccinologie, Institut Pasteur, Paris     
Lentiviral vectors as T-Cell vaccines  

______

 

grs-logo-3-square

Missions of the GRS

Objective n° 1
To further discussion and information exchange on the theme of HIV / AIDS research at the Pasteur Institute of Paris

The GRS is an interdisciplinary group of researchers involved in HIV / AIDS research at the Pasteur Institute of Paris. The GRS also involves members of other institutions such as ANRS and AP-HP in its organization. The GRS aims at improving scientific communication on HIV / AIDS and at providing information on teams involved in HIV research on the campus.

The GRS organizes a monthly meeting around and HIV / AIDS thematic that concerns fundamental research ( Retrovirology, Pathogenesis) or applied research (Vaccinology, Antiretrovirals, Immunotherapy, …).

Objective n° 2
To exchange informations and further collaborations with researchers of the International Network of Pasteur Institutes involved in HIV / AIDS research

These actions are lead in concert with the relevant directions at the Pasteur Institute. Information on GRS meetings and HIV / AIDS research at the Pasteur Institutes are posted online to facilitate the involvement of all members of the network. Special meetings are organized by the GRS upon the visit of network researchers on the Parisian campus.


Objective n° 3
To promote research and public health actions in the field of HIV / AIDS

The GRS contributes to the identification of common research themes to be developed at the Pasteur Institutes, and to the setup of collaborative programs such as PTR (Programmes Transversaux de Recherche) in the field of HIV / AIDS.

The GRS organizes a scientific watch in the field of HIV / AIDS and promotes the discussion of current HIV / AIDS topics at its monthly meetings.

 

Organization of the GRS

Organizing committee:

Advisers

  • Fernando Arenzana-Seisdedos, Shanghai Pasteur Institute
  • Françoise Barré-Sinoussi, International Direction, Pasteur Institute.
  • Pierre Charneau, Molecular Virology and Vaccinology Unit, Pasteur Institute
  • Michaela Müller-Trutwin, HIV, Inflammation, and Persistence Unit, Pasteur Institute
  • Olivier Schwartz, Virus and Immunity Unit, Pasteur Institute
  • Frédéric Tangy, Viral Genomic and Vaccination Unit, Pasteur Institute
  • Simon Wain-Hobson, Molecular Retrovirology Unit, Pasteur Institute.

Organization of GRS meetings
GRS meetings are held in general on the second Tuesday of the month. Meetings last for two hours and are organized around two to three presentations and a discussion. Invited speakers may be any researcher working in the field of HIV / AIDS, on the campus or in other institutions.

The topic of each meeting is chosen for its current interest and importance, independently of its representation on the campus. The topic does not necessarily concern HIV / AIDS in the strict sense, but may be chosen to broaden our perspective on HIV / AIDS research. Possible topics and speaker names can be proposed to the organization committee.

For each meeting, the organization committee invites two to three speakers that work at the Pasteur Institutes or in exterior organizations (INSERM, CNRS, hospitals of the AP-HP, members of coordinated actions of the ANRS, the National Agency for AIDS Research, …). Presentations are followed by a discussion, which is moderated by a researcher with authority in the field, but who does not necessarily work on HIV / AIDS.

GRS meetings are announced by posters on the Paris campus and are listed on the Conference page of the Pasteur Institute web site.

Past GRS Meetings

GRS Meetings 2017

Meeting number 93
Date 06/27/2017 at 4 PM
Topic Meeting in memory of Mark Wainberg
Organizer

Lisa Chakrabarti (Viral Pathogenesis Unit, Pasteur Institute, Paris)

Speakers Françoise BARRE-SINOUSSI
Direction Internationale, Institut Pasteur, Paris 
Introduction
Christian BRECHOT
Directeur Général de l’Institut Pasteur, Paris
Introduction
Serge EHOLIE
Université Félix Houphouet-Boigny, Abidjan
Role of Mark Wainberg in promoting access to treatment in limited resource settings
Françoise BRUN-VEZINET
Université Paris 7 Denis Diderot, Hôpital Bichat
Mark Weinberg’s achievements in the virology field
Marc DIXNEUF
Directeur Général de l’association AIDES, Paris
Role of Mark Wainberg in promoting access to prevention

Daniel Aaron DONAHUE
Unité Virus et Immunité, Institut Pasteur, Paris
Remembering Mark Wainberg as a mentor

 

Meeting number 92
Date 04/18/2017 at 4 PM
Topic Residual risk of HIV sexual transmission
Organizers

Jade Ghosn (Université Paris Descartes, EA 7327, Laboratoire de Virologie, Faculté de Médecine site Necker, Paris)

Speakers Romulus BREBAN
Unité d’Epidémiologie des Maladies Emergentes, Institut Pasteur, Paris 
Meta-analysis of the residual risk of sexual HIV transmission from efficiently treated persons
Jade GHOSN
Université Paris Descartes, EA 7327, Laboratoire de Virologie, Faculté de Médecine site Necker, Paris 
Presence of HIV RNA in the seminal fluid of efficiently treated men
Nathalie DEJUCQ
Université de Rennes, INSERM U1085 – IRSET, Rennes
Origin of HIV RNA in sperm and role of infected sperm cells

 

Meeting number 91
Date 03/10/2017 at 12 AM
Topic GRS International Seminar Series: Virology
Organizer Nicoletta Casartelli (IP)
Speaker

Leo JAMES
MRC, Cambridge, UK
Dynamic pores in HIV capsid import nucleotides for DNA synthesis

 

Meeting number 90
Date 01/25/2017 at 12 AM
Topic GRS International Seminar Series: Virology
Organizer Asier Saez-Cirion (IP) and ANRS AC32
Speaker

Aftab ANSARI
Emory University, Atlanta, USA
A non-human primate model that serves to identify an alternative to a lifetime of ART

 

GRS Meetings 2016

Meeting number 89
Date 12/15/2016 at 4 PM
Topic HIV neutralizing antibodies
Organizers Hugo Mouquet  (IP)
Speakers Mireia PELEGRIN 
Institut de Génétique Moléculaire de Montpellier 
Vaccinal effect of antiviral monoclonal antibodies: converting immunotherapies from passive to active
Pascal POIGNARD
Institut de Biologie Structurale, Université de Grenoble
Analyzing HIV broadly neutralizing antibody lineages to inform vaccine design
Mélanie Bouvin-Pley
Université de Tours
Population-level evolution of the envelope glycoprotein of HIV-1 under the selective pressure of Nabs

 

Meeting number 88
Date 05/10/2016 at 4 PM
Topic TRIM / SUMO / Interferon in antiviral responses
Organizers Lisa Chakrabarti (IP)
Speakers Jack-Christophe COSSEC
Organisation Nucléaire et Oncogénèse, Institut Pasteur, Paris
Chromatin functions of SUMO in innate immunity
Nathalie ARHEL
INSERM U941, Hôpital St Louis, Paris
TRIM5alpha regulation by SUMOylation and nuclear sequestration ensures efficient innate sensing in dendritic cells
Sébastien NISOLE
INSERM UMR S1124, Centre Universitaire des Sainst-Pères, Paris
PML/TRIM19-dependent inhibition of retroviral reverse-transcription by Daxx

 

Meeting number 87
Date 04/20/2016 at 4 PM
Topic GRS International Seminar Series: Virology
Organizer Marc Lavigne (IP) and Pascale Lesage (St Louis Hospital, Inserm)
Speaker

Henry LEVIN
Section of Transposable Elements, NICHD, NIH, Bethesda, USA
Integration site selection: how transposable elements in S. Pombe and HIV-1 in human cells identify their targets

 

Meeting number 86
Date 03/18/2016 at 2 PM
Topic GRS International Seminar Series: Virology
Organizer Nicoletta Casartelli (IP)
Speaker Massimo PIZZATO
Centre for Integrative Biology, University of Trento, Italy
SERINC, an ancient defense against retroviruses

 

Meeting number 85
Date 01/12/2016 at 4 PM
Topic CD4+ T cells and HIV tissue reservoirs
Organizers Lisa Chakrabarti (IP)
Speakers Christine BOURGEOIS
Inserm UMR 1184 / Centre IMVA, le Kremlin-Bicêtre
CD4+ T cells in adipose tissue represent a neglected HIV/SIV reservoir
Pierre DELOBEL
Inserm UMR 1043 / CHU Toulouse
Chemotaxis of CD4+ T lymphocytes and immune reconstitution of the intestinal mucosa under ART
Nabila SEDDIKI
Vaccine Research Institute, Créteil
Resident and circulating memory CD4+ T cells lacking SAMHD1 are highly sensitive to HIV-1 infection

GRS Meetings 2015

Meeting number 84
Date 10/28/2015 at 12 AM
Topic GRS International Seminar Series: Vaccinology
Organizer Lisa Chakrabarti (IP)
Speaker Zhiwei CHEN
AIDS Institute, University of Hong Kong, HK
PD-1-based vaccines for AIDS and cancer immunotherapy

 

Meeting number 83
Date 04/28/2015 at 4 PM
Topic Interactions of HIV-1 with the nuclear pore and chromatin factors
Organizers Francesca di Nunzio (IP) et Nicoletta Casartelli (IP)
Speakers Leo JAMES
Medical Research Council, Cambridge, UK
HIV-1 capsid recruits host cofactors to mediate nuclear import
Francesca DI NUNZIO
Unité de Virologie Moléculaire et Vaccinologie, Institut Pasteur, Paris
Chromatin organization at the nuclear pore favours HIV-1 replication
Fulvio MAVILIO
Genethon, Evry, France
Lentiviral gene transfer vectors and the human genome

 

Meeting number 82
Date 04/08/2015 at 4 PM
Topic HIV primary infection
Organizers Asier Saez-Cirion (IP) and the Concerted Action AC32 of ANRS
Speakers Laurence MEYER
Inserm U1018-CESP, Le Kremlin-Bicêtre
The experience of the ANRS CO6 PRIMO cohort
Jintanat ANANWORANICH
U.S. Military HIV Research Program, Walter Reed Army Institute of Research,Bethesda, USA
Treatment of acute HIV infection: A critical step to HIV remission
Laurence WEISS
Hôpital Européen Georges Pompidou et IP, Paris
Regulatory and effector CD4 responses during primary HIV infection
John FRATER
University of Oxford, UK
Biomarkers to predict viral rebound after treatment interruption – fact or fantasy?

GRS meetings have been held since 2002. The list of previous meetings can be obtained by contacting the GRS organizing committee at:  grs@pasteur.fr

Useful links

UNAIDS : Program of the United Nations on HIV/AIDS.

SIDACTION : French association providing hep to HIV infected persons, and promoting HIV/AIDS prevention and research.

ANRS : French National Agency for the fight of HIV/AIDS and viral hepatitis B and C.

Medscape HIV/AIDS : Informations on HIV/AIDS for health professionals, summaries of AIDS conferences.

AMEDEO HIV infection : Bibliographic information service on HIV/AIDS.

HIV sequence database : Repertory of HIV nucleotide sequences and epitopes.

CROI 2016 presentations : listen to webcasts and podcasts of presentations made at the CROI conference (Conference on Retroviruses and Opportunistic Infections) which was held in Boston in February 2016.

R4P 2016 presentations : listen to webcasts of presentations made at the “HIV Research for Prevention” conference which was held in Chicago in October 2016.

 

Contact us

For more information on the GRS meetings, or to suggest topics for future meetings, contact us at:

grs@pasteur.fr

Last updated Dec. 20, 2016, by Lisa Chakrabarti.