Timeline

Michel Cohen-Tannoudji
Group Leader
26 Mar 2019
publication

PDGF signaling in primitive endoderm cell survival is mediated by PI3K-mTOR through p53-independent mechanism

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17 Jan 2019
publication

Transcription factor activity and nucleosome organization in mitosis

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26 Nov 2018
publication

Notchless defines a stage-specific requirement for ribosome biogenesis during lineage progression in adult skeletal myogenesis

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21 Sep 2018
publication

Mouse adult hematopoietic stem cells actively synthetize ribosomal RNA

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17 Sep 2018
news

Club des Belles Souris 2018

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03 Sep 2018
event

PhD Thesis defense: “In vivo exploration of the impact of ribosome biogenesis alterations on intestinal homeostasis and tumorigenesis in the adult mouse”

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24 Jan 2018
publication

Argonaute 2 Is Required for Extra-embryonic Endoderm Differentiation of Mouse Embryonic Stem Cells

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25 Sep 2017
publication

ICM conversion to epiblast by FGF/ERK inhibition is limited in time and requires transcription and protein degradation

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09 Jun 2017
publication

A multiscale model of early cell lineage specification including cell division

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09 Jun 2017
publication

A multiscale model of early cell lineage specification including cell division

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03 Mar 2017
news

Club des Belles Souris 2017

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17 Feb 2017
publication

Optimization of the production of knock-in alleles by CRISPR/Cas9 microinjection into the mouse zygote

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10 Oct 2016
publication

Mitotic binding of Esrrb marks key regulatory regions of the pluripotency network

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20 Sep 2016
news

Club des Belles Souris 2016

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02 Dec 2015
project

Follicular growth and ovarian endocrine function

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19 Nov 2015
course

Mouse Genetics Course

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01 Nov 2015
publication

NOTCH activation interferes with cell fate specification in the gastrulating mouse embryo

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17 Sep 2015
news

Club des Belles Souris

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17 Sep 2015
project

Epiblast/Primitive Endoderm specification and differentiation during early mouse development

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27 Aug 2015
tool

Notch Activity Sensor (NAS) transgenic mouse line

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27 Aug 2015
tool

The H-2Z1 transgenic line

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16 Jul 2015
team

Early Mammalian Development & Stem Cell Biology

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12 Jun 2015
publication

Ribosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cells

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29 Aug 2014
publication

Oocyte-specific inactivation of Omcg1 leads to DNA damage and c-Abl/TAp63-dependent oocyte death associated with dramatic remodeling of ovarian somatic cells

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29 May 2014
publication

Notchless is required for axial skeleton formation in mice

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23 Sep 2013
publication

Notchless-dependent ribosome synthesis is required for the maintenance of adult hematopoietic stem cells

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01 Sep 2013
publication

PDGF signaling is required for primitive endoderm cell survival in the inner cell mass of the mouse blastocyst

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23 May 2012
publication

Omcg1 is critically required for mitosis in rapidly dividing mouse intestinal progenitors and embryonic stem cells

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23 May 2012
publication

Integration of H-2Z1, a somatosensory cortex-expressed transgene, interferes with the expression of the Satb1 and Tbc1d5 flanking genes and affects the differentiation of a subset of cortical interneurons

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19 Jan 2012
publication

[Reconsidering the roles of female germ cells in ovarian development and folliculogenesis]

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27 Dec 2011
publication

Naive and primed murine pluripotent stem cells have distinct miRNA expression profiles

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28 Apr 2011
publication

[A new era in rat genetics]

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01 Jan 2011
publication

DNA-RNA hybrids contribute to the replication dependent genomic instability induced by Omcg1 deficiency

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01 Nov 2009
publication

Numb promotes an increase in skeletal muscle progenitor cells in the embryonic somite

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17 Mar 2009
publication

Distinct phenotypic and functional features of CADASIL mutations in the Notch3 ligand binding domain

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13 Jan 2009
publication

CARP2 deficiency does not alter induction of NF-kappaB by TNFalpha

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01 Dec 2007
publication

[Nobel Prize 2007 for Medicine to Mario Capecchi, Martin Evans and Oliver Smithies: the mutant mice to order]

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21 Nov 2007
publication

Cell cycle regulation during early mouse embryogenesis

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23 Mar 2007
publication

Conditional knock-out reveals that zygotic vezatin-null mouse embryos die at implantation

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01 Jan 2007
publication

[Notch signalling pathway and early mammalian embryogenesis]

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01 Jul 2006
publication

RBP-Jkappa-dependent notch signaling is dispensable for mouse early embryonic development

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16 Jun 2006
publication

Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation

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01 Jun 2006
publication

Nas transgenic mouse line allows visualization of Notch pathway activity in vivo

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01 May 2006
publication

The murine ortholog of notchless, a direct regulator of the notch pathway in Drosophila melanogaster, is essential for survival of inner cell mass cells

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01 Mar 2006
publication

The cell cycle of early mammalian embryos: lessons from genetic mouse models

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01 Dec 2005
publication

The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice

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01 Jul 2005
publication

Impaired mitotic progression and preimplantation lethality in mice lacking OMCG1, a new evolutionarily conserved nuclear protein

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01 Mar 2005
publication

[Inhibition of endocytic recycling by Rififylin]

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31 Dec 2004
publication

Development of a targeted transgenesis strategy in highly differentiated cells: a powerful tool for functional genomic analysis

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01 Oct 2004
publication

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development

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30 Jun 2004
publication

Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment

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21 Aug 2002
publication

Transcript map of the Ovum mutant (Om) locus: isolation by exon trapping of new candidate genes for the DDK syndrome

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01 Sep 2001
publication

Genome engineering via homologous recombination in mouse embryonic stem (ES) cells: an amazingly versatile tool for the study of mammalian biology

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15 Sep 2000
publication

A 2-Mb YAC/BAC-based physical map of the ovum mutant (Om) locus region on mouse chromosome 11

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01 Jun 2000
publication

lacZ and ubiquitously expressed genes: should divorce be pronounced?

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01 Feb 2000
publication

BALB/c alleles at modifier loci increase the severity of the maternal effect of the “DDK syndrome”

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01 Jan 2000
publication

lacZ sequences prevent regulated expression of housekeeping genes

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01 Sep 1999
publication

Role of thalamic axons in the expression of H-2Z1, a mouse somatosensory cortex specific marker

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23 Aug 1999
publication

In vivo, villin is required for Ca(2+)-dependent F-actin disruption in intestinal brush borders

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15 Jun 1999
publication

Specification of somatosensory area identity in cortical explants

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01 Dec 1998
publication

Nonpermissiveness for mouse embryonic stem (ES) cell derivation circumvented by a single backcross to 129/Sv strain: establishment of ES cell lines bearing the Omd conditional lethal mutation

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01 Oct 1998
publication

Beyond ‘knock-out’ mice: new perspectives for the programmed modification of the mammalian genome

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01 Mar 1998
publication

I-SceI-induced gene replacement at a natural locus in embryonic stem cells

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01 Jun 1996
publication

CD4 T cell tolerance to nuclear proteins induced by medullary thymic epithelium

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01 Feb 1996
publication

A high-resolution map around the locus Om on mouse Chromosome 11

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01 Feb 1996
publication

A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2

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01 Feb 1996
publication

Medullary thymic epithelial cells induce tolerance to intracellular proteins

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01 Dec 1995
publication

Molecular heterogeneity of progenitors and radial migration in the developing cerebral cortex revealed by transgene expression

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01 Dec 1995
publication

Disruption of murine Hexa gene leads to enzymatic deficiency and to neuronal lysosomal storage, similar to that observed in Tay-Sachs disease

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01 Sep 1995
publication

Developmental expression of H-2K major histocompatibility complex class I transgenes requires the presence of proximal introns

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01 May 1994
publication

Compartmentalization of lambda subtype expression in the B cell repertoire of mice with a disrupted or normal C kappa gene segment

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31 Mar 1994
publication

Early determination of a mouse somatosensory cortex marker

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17 Dec 1993
publication

Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain

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01 Oct 1992
publication

Unexpected position-dependent expression of H-2 and beta 2-microglobulin/lacZ transgenes

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