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© Research
Publication : Mammalian genome : official journal of the International Mammalian Genome Society

A high-resolution map around the locus Om on mouse Chromosome 11

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Mammalian genome : official journal of the International Mammalian Genome Society - 01 Feb 1996

Baldacci PA, Cohen-Tannoudji M, Kress C, Pournin S, Babinet C

Link to Pubmed [PMID] – 8835527

Mamm. Genome 1996 Feb;7(2):114-6

The locus Om (ovum mutant) identified in the mouse strain DDK affects the viability of (DDK x non-DDK)F1 preimplantation embryos. We previously located this locus on Chromosome (Chr) 11 close to Scya2 (Baldacci et al. Mamm. Genome 2, 100-105, 1992). Here we report a high-resolution map of the region around Om based on a large number of backcross individuals. The same region has been analyzed on the EUCIB backcross, and the two maps have been compared. The results define the proximal and distal boundaries for the Om mutation as Scya2 and D11Mit36 respectively. The distance between these two markers is about 2 cM. These data should facilitate the positional cloning and molecular characterization of Om.

http://www.ncbi.nlm.nih.gov/pubmed/8835527