Ligne de temps
Michel Cohen-Tannoudji
Chef(fe) de Groupe
13 janv. 2024
01 sept. 2022
publication
H3K9 tri-methylation at Nanog times differentiation commitment and enables the acquisition of primitive endoderm fate.
Lire plus22 juil. 2022
publication
OCT4 activates a Suv39h1-repressive antisense lncRNA to couple histone H3 Lysine 9 methylation to pluripotency.
Lire plus21 juin 2022
publication
NANOG initiates epiblast fate through the coordination of pluripotency genes expression.
Lire plus01 janv. 2021
publication
Microfabricated Device for High-Resolution Imaging of Preimplantation Embryos.
Lire plus18 déc. 2020
publication
Fast In Vitro Procedure to Identify Extraembryonic Differentiation Defect of Mouse Embryonic Stem Cells.
Lire plus17 juin 2020
publication
Direct Readout of Neural Stem Cell Transgenesis with an Integration-Coupled Gene Expression Switch.
Lire plus30 avr. 2020
publication
Compensation between Wnt-driven tumorigenesis and cellular responses to ribosome biogenesis inhibition in the murine intestinal epithelium
Lire plus10 janv. 2020
10 oct. 2019
publication
CTCF confers local nucleosome resiliency after DNA replication and during mitosis
Lire plus26 mars 2019
publication
PDGF signaling in primitive endoderm cell survival is mediated by PI3K-mTOR through p53-independent mechanism
Lire plus17 janv. 2019
26 nov. 2018
publication
Notchless defines a stage-specific requirement for ribosome biogenesis during lineage progression in adult skeletal myogenesis
Lire plus21 sept. 2018
17 sept. 2018
03 sept. 2018
event
PhD Thesis defense: “In vivo exploration of the impact of ribosome biogenesis alterations on intestinal homeostasis and tumorigenesis in the adult mouse”
Lire plus24 janv. 2018
publication
Argonaute 2 Is Required for Extra-embryonic Endoderm Differentiation of Mouse Embryonic Stem Cells
Lire plus25 sept. 2017
publication
ICM conversion to epiblast by FGF/ERK inhibition is limited in time and requires transcription and protein degradation
Lire plus09 juin 2017
publication
A multiscale model of early cell lineage specification including cell division
Lire plus03 mars 2017
17 févr. 2017
publication
Optimization of the production of knock-in alleles by CRISPR/Cas9 microinjection into the mouse zygote
Lire plus10 oct. 2016
publication
Mitotic binding of Esrrb marks key regulatory regions of the pluripotency network
Lire plus20 sept. 2016
02 déc. 2015
19 nov. 2015
01 nov. 2015
publication
NOTCH activation interferes with cell fate specification in the gastrulating mouse embryo
Lire plus17 sept. 2015
17 sept. 2015
project
Epiblast/Primitive Endoderm specification and differentiation during early mouse development
Lire plus27 août 2015
27 août 2015
16 juil. 2015
12 juin 2015
publication
Ribosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cells
Lire plus09 juin 2015
09 juin 2015
11 mai 2015
29 août 2014
publication
Oocyte-specific inactivation of Omcg1 leads to DNA damage and c-Abl/TAp63-dependent oocyte death associated with dramatic remodeling of ovarian somatic cells
Lire plus29 mai 2014
23 sept. 2013
publication
Notchless-dependent ribosome synthesis is required for the maintenance of adult hematopoietic stem cells
Lire plus01 sept. 2013
publication
PDGF signaling is required for primitive endoderm cell survival in the inner cell mass of the mouse blastocyst
Lire plus23 mai 2012
publication
Omcg1 is critically required for mitosis in rapidly dividing mouse intestinal progenitors and embryonic stem cells
Lire plus23 mai 2012
publication
Integration of H-2Z1, a somatosensory cortex-expressed transgene, interferes with the expression of the Satb1 and Tbc1d5 flanking genes and affects the differentiation of a subset of cortical interneurons
Lire plus19 janv. 2012
publication
[Reconsidering the roles of female germ cells in ovarian development and folliculogenesis]
Lire plus27 déc. 2011
publication
Naive and primed murine pluripotent stem cells have distinct miRNA expression profiles
Lire plus28 avr. 2011
01 janv. 2011
publication
DNA-RNA hybrids contribute to the replication dependent genomic instability induced by Omcg1 deficiency
Lire plus01 nov. 2009
publication
Numb promotes an increase in skeletal muscle progenitor cells in the embryonic somite
Lire plus17 mars 2009
publication
Distinct phenotypic and functional features of CADASIL mutations in the Notch3 ligand binding domain
Lire plus13 janv. 2009
01 déc. 2007
publication
[Nobel Prize 2007 for Medicine to Mario Capecchi, Martin Evans and Oliver Smithies: the mutant mice to order]
Lire plus21 nov. 2007
23 mars 2007
publication
Conditional knock-out reveals that zygotic vezatin-null mouse embryos die at implantation
Lire plus01 janv. 2007
01 juil. 2006
publication
RBP-Jkappa-dependent notch signaling is dispensable for mouse early embryonic development
Lire plus16 juin 2006
publication
Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation
Lire plus01 juin 2006
publication
Nas transgenic mouse line allows visualization of Notch pathway activity in vivo
Lire plus01 mai 2006
publication
The murine ortholog of notchless, a direct regulator of the notch pathway in Drosophila melanogaster, is essential for survival of inner cell mass cells
Lire plus01 mars 2006
01 déc. 2005
publication
The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice
Lire plus01 juil. 2005
publication
Impaired mitotic progression and preimplantation lethality in mice lacking OMCG1, a new evolutionarily conserved nuclear protein
Lire plus01 mars 2005
31 déc. 2004
publication
Development of a targeted transgenesis strategy in highly differentiated cells: a powerful tool for functional genomic analysis
Lire plus01 oct. 2004
publication
Developmental expression of the Notch signaling pathway genes during mouse preimplantation development
Lire plus30 juin 2004
publication
Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment
Lire plus21 août 2002
publication
Transcript map of the Ovum mutant (Om) locus: isolation by exon trapping of new candidate genes for the DDK syndrome
Lire plus01 sept. 2001
publication
Genome engineering via homologous recombination in mouse embryonic stem (ES) cells: an amazingly versatile tool for the study of mammalian biology
Lire plus15 sept. 2000
publication
A 2-Mb YAC/BAC-based physical map of the ovum mutant (Om) locus region on mouse chromosome 11
Lire plus01 juin 2000
01 févr. 2000
publication
BALB/c alleles at modifier loci increase the severity of the maternal effect of the “DDK syndrome”
Lire plus01 janv. 2000
01 sept. 1999
publication
Role of thalamic axons in the expression of H-2Z1, a mouse somatosensory cortex specific marker
Lire plus23 août 1999
publication
In vivo, villin is required for Ca(2+)-dependent F-actin disruption in intestinal brush borders
Lire plus15 juin 1999
01 déc. 1998
publication
Nonpermissiveness for mouse embryonic stem (ES) cell derivation circumvented by a single backcross to 129/Sv strain: establishment of ES cell lines bearing the Omd conditional lethal mutation
Lire plus01 oct. 1998
publication
Beyond ‘knock-out’ mice: new perspectives for the programmed modification of the mammalian genome
Lire plus01 mars 1998
01 juil. 1997
publication
The acceleration-velocity relationship: identification of normal and spastic upper extremity movement.
Lire plus01 juin 1996
publication
CD4 T cell tolerance to nuclear proteins induced by medullary thymic epithelium
Lire plus01 févr. 1996
01 févr. 1996
publication
A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2
Lire plus01 févr. 1996
01 déc. 1995
publication
Molecular heterogeneity of progenitors and radial migration in the developing cerebral cortex revealed by transgene expression
Lire plus01 déc. 1995
publication
Disruption of murine Hexa gene leads to enzymatic deficiency and to neuronal lysosomal storage, similar to that observed in Tay-Sachs disease
Lire plus01 sept. 1995
publication
Developmental expression of H-2K major histocompatibility complex class I transgenes requires the presence of proximal introns
Lire plus01 mai 1994
publication
Compartmentalization of lambda subtype expression in the B cell repertoire of mice with a disrupted or normal C kappa gene segment
Lire plus31 mars 1994
17 déc. 1993
publication
Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain
Lire plus01 oct. 1992
publication