Analytical techniques [449]
Régis Tournebize
Photonic BioImaging (UTechS PBI)
Nathalie Sauvonnet
Biomaterials and Microfluidics
Intracellular traffic and cell compartmentalization Eukaryotic cells contain extensive internal membranes defining many compartments having each specific functions. However these organelles are constantly moving and reshaping, still retaining their identity. The maintenance of cell […]
Timothée Bruel
Antiviral Activities of Antibodies
Since the beginning of my career, my goal has been to understand the mechanisms of effector immune responses to viruses and the related viral countermeasures. During my thesis, I studied the origin of type […]
François Schweisguth
Dynamics of Developmental Decisions in Drosophila
Francois Schweisguth studied at the Ecole Normale Superieure in Paris (1983-88) and obtained a PhD in Developmental Biology in 1990 under the supervision of Jean-Antoine Lepesant (IJM, Paris) and Alain Vincent (CBD, Toulouse). He […]
Benno Schwikowski
Computational Systems Biomedicine
Gérald Spaeth
U1201 – Genetic and molecular basis of host-parasite interactions
Dr. Gerald Späth currently holds a Research Director position at the Institut Pasteur in Paris, where he directs the Unit ‘Parasitologie moléculaire et Signalisation’ (12 members) and the Department ‘Parasites and Insect Vectors’ (ca. […]
Pascale Pescher
Molecular Parasitology and Signaling
Pascale Pescher is a research engineer in the unit ‘Parasitologie moléculaire et signalisation’. She started her career working on host-mycobacteria interactions and since 2006 joined the field of Leishmania research studying the molecular basis […]
Najma Rachidi
Signalling and host-parasite interactions
Dr. Najma Rachidi is a senior Researcher and the leader of the molecular parasitology team in the PARSIG unit. Her team investigates Host-pathogen interactions to (i) understand how Leishmania survives in immune cells, which […]
Phanramphoei Frantz
Institut Pasteur-Oncovita joint laboratory
Maxime Chazal
Virus sensing and signaling
Christian Mitri
Biology of Insect Vectors and their Pathogens
From 2001 to 2005 I did my Ph.D in Montpellier (South of France) at the Institut of Functional Genomic. I worked on Drosophila melanogaster and I characterized a new G-Protein Coupled Receptor, only found […]
Thermodynamic stability of macromolecules
Circular dichroism (CD) spectroscopy allows the determination of secondary and tertiary structures, the analysis of conformational changes and the measure of thermal and chemical stability of folding. Differential Scanning Calorimetry (DSC) gives access to […]
Secondary and tertiary structures of macromolecules
Circular dichroism (CD) allows the measurement of secondary and tertiary structures, the analyse of conformational changes, the kinetic of folding and the thermal and chemical stability of folding. Fluorescence spectroscopy gives access to the […]
Size and Shape of Macromolecules and their assemblies
Analytical Ultracentrifugation gives access to the mass and shape of macromolecules in solution, allowing to evaluate their oligomerization state, their stoichiometry and the equilibrium constant of assemblies. Dynamic Light Scattering (cuvette or microplaque) allows […]
Stoichiometry of Macromolecular Assemblies
Static Light Scattering allows to measure the mass and intrinsic viscosity of macromolecules Analytical Ultracentrifugation gives access to the oligomerization state and the stoichiometry of molecular assemblies