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© Jean-Claude Antoine
Leishmania mexicana amazonensis

About

Pascale Pescher is a research engineer in the unit ‘Parasitologie moléculaire et signalisation’. She started her career working on host-mycobacteria interactions and since 2006 joined the field of Leishmania research studying the molecular basis of Leishmania donovani virulence. Applying systems-level analyses (genomic, transcriptomic, proteomic, phosphoproteomic and metabolomic) to a physiologically relevant experimental model for Leishmania donovani infection, she investigates how the parasite adapts to its hosts to reveal potential druggable pathways and new bio-markers.  She is currently part of two international projects with the aim to study evolutionary adaptation: “Modelling and functional analysis of clonal Evolution in Leishmania – possible role of non-coding RNAs and RNA modification” with partners from Israel, and “H2020 LeiSHield-MATI RISE”, project she is co-coordinating with G. Spaeth and G. Bussotti that implicates Pasteur institutes from the international network and European research institutions. She is co-author of 30 publications including 16 on Leishmania.

Projects

CV

EDUCATION

  • 2015 – Expérimentation animale, concepteur de projets
  • 2002 – DEPHE, mention très bien, validation Master 2, Sorbonne Paris, France
  • 1988 – DPCT biochimie/biologie, CNAM Paris, France
  • 1981 – Bac F7 biochimie, Cachan, France

RESEARCH and Professional EXPERIENCE

  • 2008-present – Ingénieure de recherche confirmée, Institut Pasteur, Paris, France
  • 1983-2008 – Technicienne, Institut Pasteur, Paris, France

SCIENTIFIC ACTIVITIES

  • 30 publications, 3 oral presentations and 10 posters in international congresses – Hirsch h index:13
  • Co-organization of 2 departmental retreats Co-coordinator of the LeiSHield-MATI – RISE – H-2020 project Reviewer for PLOS Neglected Tropical diseases

TEACHING ACTIVITIES

  • 1 thesis (Leishmania virulence) currently in co-supervision
  • Teaching in masters formations at the Institut Pasteur
  • Teaching/supervision of researchers, Masters and graduate students

ADMINISTRATIVE RESPONSIBILITIES and EXPERTISE

  • From 2013 to 2017, member of the COMESP (scientific evaluation committee) of the Institut Pasteur.
  • Scientific responsible of the ‘laboratoire de préparation’
  • Correspondent for the animal facility
  • Since 2014 designer and responsible for animal experimentation for the unit
  • Member of the Biomics committee users for the PIV department
  • Member of the MSBio committee users

Publications

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