On the cover: Type IV pili (T4P), long and flexible appendages at the surface of many bacteria, are critical virulence factors. Pili of enterohemorrhagic E. coli (EHEC), an important human pathogen, are polymers of […]
In the Cell, Proteins and Nucleic Acid assemble into larger structures, called macromolecular complexes. These complexes are specialized biological machineries that accomplish fundamental tasks that are at the basis of life. I employ computer modeling […]
After a PhD in Neuroscience from the University of Lyon-I in 1995, he joined the Institut Pasteur (Paris) where resorting to dozen identified deafness genes, several of which are involved in Usher syndrome (deafness […]
My research interests are mainly focused on the structure-function relationships of macromolecules through multidisciplinary approaches. My studies have been concentrated on crucial enzymes belonging to the nucleotide metabolism, in particular nucleoside monophosphate kinases (NMPKs) […]
Medicinal chemistry in an academic environment: removing “chemical blind spots” Yves L. Janin The task of doing good MedChem in an academic environment has been the subject of two recent comments which provide excellent […]
Pedro Oliveira graduated in Biological Engineering from University of Lisbon (Instituto Superior Técnico, IST) in 2005, worked as research assistant at University College London (2005), and completed a PhD degree in Biotechnology from IST […]
Born and bred in Alsace, France, I did my PhD at the Institut de Biologie Moleculaire et Cellulaire of Strasbourg, in the laboratory of Prof. Jules Hoffmann under the supervision of Dr. Dominique Ferrandon. […]