Francois Schweisguth studied at the Ecole Normale Superieure in Paris (1983-88) and obtained a PhD in Developmental Biology in 1990 under the supervision of Jean-Antoine Lepesant (IJM, Paris) and Alain Vincent (CBD, Toulouse). He was a HFSP post-doctoral fellow with Pr. J. W. Posakony at the University of California San Diego (1990-93). He joined the CNRS in 1992 and obtained a group leader position (ATIPE-CNRS) at the Ecole Normale Superieure, Biology Dept (Paris) in 1996. He moved to the Institut Pasteur (Paris) to head a Pasteur Unit in 2008. He was awarded a Silver Medal by the CNRS in 2006 and was elected as an EMBO member in 2012. He currently holds a CNRS Research Director position. He is the Director of the CNRS UMR3738 (since 2011), the head of the BDCS Dept (since 2016), a co-coordinator the Labex REVIVE (since 2011) and a co-director of a Pasteur/REVIVE course on Stem Cell Biology (since 2013). His research focuses on the cell biology of Notch, the control of cell fate, the regulation of epithelial morphogenesis and tissue homeostasis using Drosophila as a model system.
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Position title : Directeur de Recherche CE CNRS, Director of the CNRS Unit UMR3738, Head of the BDCS Dept and Unit Head at the Institut Pasteur
Education/Training : 1983-88: Ecole Normale Supérieure, Paris 1996-90: PhD, University Paris 6, Institut Jacques Monod, Lepesant lab. 1990-93: post-doc, University of California San Diego, Posakony lab.
Research and Professional Experience :1993-96: Junior Scientist at the CNRS, Institut Jacques Monod (Paris) 1997-2008: ATIP Group Leader, Ecole Normale Supérieure (Paris) 2000- : Directeur de Recherche CNRS 2008- : Head of Unit, Institut Pasteur (Paris) 2010- : Director of the CNRS Unit URA2578/UMR3738, Institut Pasteur (Paris) 2011- : Co-coordinator of the LabEX Revive 2016- Head of the BDCS Dept
Honors : Prix Charles-Leopold Mayer from the French Academy of Science (2015) EMBO member (2012) Prix Zermati from the Fondation de France (2012) Silver Medal of the CNRS (2006) Prix Jaffé from the French Academy of Science (2005) Bronze Medal of the CNRS (1996)
Publications
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2017Neuralized regulates Crumbs endocytosis and epithelium morphogenesis via specific Stardust isoforms, J. Cell Biol. 2017 Apr;.
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2017Self-organized Notch dynamics generate stereotyped sensory organ patterns in Drosophila, Science 2017 Apr;.
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2017Response to “Does pupal communication influence Wolbachia-mediated cytoplasmic incompatibility?”, Curr. Biol. 2017 Jan;27(2):R55-R56.
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2016Control of Neural Daughter Cell Proliferation by Multi-level Notch/Su(H)/E(spl)-HLH Signaling, PLoS Genet. 2016 Apr;12(4):e1005984.
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2015A Wolbachia-Sensitive Communication between Male and Female Pupae Controls Gamete Compatibility in Drosophila, Curr. Biol. 2015 Sep;25(18):2339-48.
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2015Planar Cell Polarity Breaks the Symmetry of PAR Protein Distribution prior to Mitosis in Drosophila Sensory Organ Precursor Cells, Curr. Biol. 2015 Apr;25(8):1104-10.
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2015Asymmetric cell division in the Drosophila bristle lineage: from the polarization of sensory organ precursor cells to Notch-mediated binary fate decision, Wiley Interdiscip Rev Dev Biol 2015 May-Jun;4(3):299-309.
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2014A fluorescent tagging approach in Drosophila reveals late endosomal trafficking of Notch and Sanpodo, J. Cell Biol. 2014 Nov;207(3):351-63.
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2014Insensible is a novel nuclear inhibitor of Notch activity in Drosophila, PLoS ONE 2014;9(6):e98213.
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2014Imogene: identification of motifs and cis-regulatory modules underlying gene co-regulation, Nucleic Acids Res. 2014 Jun;42(10):6128-45.
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