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  • whocc
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  • patent
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  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
  • Graduate Student
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
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About

 

The objective of the platform is to bridge biology and engineering in order to help the development of biomedical projects with a strong technological focus. Practically we provide the campus with essential technological bricks and expertise in microfluidics and biomaterials. Since May 2015 we developed in-house capabilities in the field of microfabrication, photo- and soft-lithography, multifactorial cell screening and automated live cell imaging especially targeted for the better understanding of complex cell-microenvironment interactions. We also provide assistance with the deployment of advanced 3D cell culture and organ-on-chip systems.

Take me to the booking system (PPMS)

Services

Booking site

Organ-on-Chip technology – Emulate

Organ-on-chip center Working with Emulate technology Design your Organ (Intestine, Liver, Lungs, Brain, Lymphoid organs…) The 2 chambers chip developped by Emulate can be seeded with any type of cells allowing us to do […]

Design and Production of Microfluidic Chips

BMcf is fully geared towards meeting the need in term of microfluidic chip design and production. The team will provide expertise, protocols and equipment to allow the interested scientists to produce “homemade” microfluidic devices.

Advanced 3D cell culture

We provide a library of 3D cell culture scaffolds with tunable biophysical and biochemical properties.   

Soft-lithography bench

The pipeline is targeted for the production of microfluidics chips in PDMS (silicone elastomer) . Masters produced by contact photolithography are (negatively) replicated in PDMS under dust-free conditions. The bonding of the chips are performed […]

Contact Photolithography

The photolithography station is dedicated to microfabrication applications. The concept is based on the using 1-UV light, 2-Binary masks and 3-photosensitive resins to produce 3D objects with resolution <1μm.

Equipments

Booking site

Spincoater • SCS • 6800

Programmable spincoater dedicated to the production of thin layers of PDMS

2 • Microfluidic syringe pumps • Cetoni • neMESYS

Computer controlled (programmable) syringe pump system dedicated to microfluidic chip perfusion. One controller plus two low pressure modules and a pressure sensor.

Inverted microscope for live cell imaging • Zeiss • Axiovert

Inverted microscope for live cell imaging capabilities. The microscope is built for speed in order to reduce the interval between time points when acquiring a timelapse experiment. Standard LED fluorescence is available (Colibri system). […]

Plasma cleaner • diener • Femto

Oxygen plasma cleaner. Applications: surface activation, PDMS bonding, cleaning. Controllable vacuum, gas injection, power, treatment time.  

Mask aligner • Süss Microtec • MJB4

Manual mask aligner equipped with a topside microscope and dual objectives. Micrometric screws allow a precise mask-substrate alignment.   

Former Members

2000
2000
Name
Position
2016
2020
Raphaël Gayet
Visiting Scientist
2016
2020
Yasemin Atiyas
Undergraduate Student
2016
2020
Camille Berthault
2016
2020
Igor Molybog
Undergraduate Student
2016
2020
Stefan Rouach
Undergraduate Student
2016
2020
Charlotte Bouquerel
Graduate Student
2016
2020
Anette Funfak
Post-doc

Projects

Project
Ongoing
6 Members

Impact of gut mechanical forces and 3D architecture on the intestine homeostasis during pathogen interaction and in cancer disease

Nathalie Sauvonnet (PI)

The intestine, and in particular the colon, comprising a mucus blanket, an epithelial monolayer and the lamina propria rich in immune cells, is constantly subjected to shear stress (flow) and peristaltic motion (stretching), both […]
Project
Ongoing
3 Members

Hydraulically Actuated Hydrogel Layers

Samy Gobaa (PI)

The goal of this project is to develop a new organ-on-chip microfluidic device based on the actuation of thin hydrogel layers. Indeed, hydrogels possess interesting properties, compared to the commonly used perforated PDMS membranes. […]
Project
Ongoing
12 Members

Organ-on-Chip Center

Samy Gobaa (PI)

What’s best to study humans and their infectious deseases than Human emulation system ? It’s now possible at Pasteur to develop real Organs-on-chips with cells from different sources, patient derived or cell line. At […]
Project
Ongoing
2 Members

iLite

Samy Gobaa (PI)

The goals of this project are to build an external bioartificial liver, a liver-on-chip as well as a bioengineered liver. In the present project, bioconstruction of the liver will be performed by the assembly […]
Project
Ongoing
15 Members

Microfluidics@Pasteur

Samy Gobaa (PI)

Welcome to the club! Welcome to Microfluidics@Pasteur! Our goal is to serve as the major entry point to all the scientists on the campus (beginners and experts) interested in undertaking projects where microfluidics is involved. Our […]

Fundings

Publications

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Contact

Phone: +33 1 44 38 92 75 Email: bioengineeringservices@pasteur.fr; samy.gobaa@pasteur.fr Address: 25-28 Rue du Docteur Roux 75015, Paris France