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  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
  • Graduate Student
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
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Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
01
Jan 2020
Ending Date
31
Dec 2022
Status
Ongoing
Members
3
Structures
5
Instituts
1

About

Our objective is to generate inner ear organoids that can recapitulate in vitro the initial steps of the cochlear epithelium formation. In particular, we aim at generating these organoids in a micro-environment that allows us to control the spatial and temporal distribution of morphogens and other diffusible biochemical factors known to be essential for the determination of the cochlear axes. To this end, the team is combining cutting edge microfluidic and biomaterial technologies with high throughput imaging and image analysis to promote and monitor cochlear differentiation from embryonic stem cells in multiple organoids. This interdisciplinary work initiated at the Hearing Institute is performed in collaboration with the Biomaterial & Microfluidic facility at the Institut Pasteur (Paris), the Institut Pasteur of Korea, and the National University of Seoul.

Fundings