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CV

Education & Research activity

2017 – present : Post-doctoral Researcher                                                                                                      

Institut Pasteur, Paris, France

Laboratory of Dr. Marc Lecuit, Biology of Infection Unit

  • Project : Understanding the molecular mechanisms of Listeria translocation across the intestinal epithelium 

2009-2016 : Ph.D. in Biochemistry, Cell and Molecular Biology (BCMB)                                                       

Weill Graduate School of Medical Science of Cornell University, New York, NY, USA

(Affiliated with Memorial Sloan Kettering Cancer Center, New York, NY, USA)

Laboratory of Dr. Bryan M.F. Tsou, Memorial Sloan Kettering Cancer Center

  • Thesis : Shape and copy number control of centriole duplication

2008-2009 : Professional Research Associates

Skirball Institute of Biomolecular Medicine, New York University Medical School. New York, NY, USA

Laboratory of Dr. Greg S. B. Suh

  • Project: Identification of mosquito ortholog of Drosophila olfactory receptor IR64A

2007-2008 : Research Associates

School of Biological Sciences, Seoul National University, Seoul, South Korea

Laboratory of Dr. Yeonhee Choi, Seoul National University

2005-2007 : M.S. in Biological Sciences                                                                                                            

School of Biological Sciences, Seoul National University, Seoul, South Korea

Laboratory of Dr. Yeonhee Choi, Seoul National University

  • Thesis : Mitotic Epigenetic Inheritance of Meristematic DNA Demethylation

2000-2004 : B.S. in Biological Sciences                                                                                                             

School of Biological Sciences

Seoul National University, Seoul, South Korea

2003 : Summer Semester in University of California, Berkeley, USA                                                                                                                                

Skills and Expertise

  • Organoid culture
  • Light Sheet Fluorescent Microscopy (LSFM)
  • Super-resolution microscopy techniques :3D-Structured Illumination Microscopy (3D-SIM), Stochastic Transfer of Resonance Microscopy (STORM)
  • Basic understanding of Stimulated Emission Depletion Microscopy (STED)
  • CRISPR/Cas9 gene editing in human cells
  • Adeno-associated virus-mediated homologous recombination in human somatic cells
  • Basic understanding of human, yeast, Drosophila, and plant genetics

Publication

Kim, M., O’Rouke B.P., Soni, R. K., Jallepalli, P.V., Hendrickson, R., and Tsou, M.F. (2016) Promotion and suppression of centriole duplication are catalytically coupled through PLK4. Cell Rep 16(5):1195-1203

Fong, C.S., Mazo, G., Das, T., Goodman, J., Kim, M., O’Rouke B.P., Izquierdo, D., and Tsou, M.F. (2016) 53BP1 and USP28 mediated p53-dependent cell cycle arrest in response to centrosome loss and prolonged mitosis. Elife 2016;5:e16270

Kim, M., Fong, C.S. and Tsou, M.F. (2014) Centriole duplication: when PLK4 meets Ana2/STIL. Curr Biol 24(21):R1046-1048

Fong, C.S.*, Kim, M.*, Yang, T.T., Liao, J.C. and Tsou, M.F. (2014) SAS-6 assembly template by the lumen of cartwheel-less centriole precedes centriole duplication. Dev Cell 30(2):238-245

(* equal contribution)

Kim, M., Ohr, H., Lee, J., Hynn, Y., Fischer, R.L. and Choi, Y. (2008) Temporal and spatial downregulation of Arabidopsis MET1 activity results in global DNA hypomethylation and developmental defects. Molecules and Cells 26 (6):611-615

Publications

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