Education & Research activity
2017 – present : Post-doctoral Researcher
Institut Pasteur, Paris, France
Laboratory of Dr. Marc Lecuit, Biology of Infection Unit
- Project : Understanding the molecular mechanisms of Listeria translocation across the intestinal epithelium
2009-2016 : Ph.D. in Biochemistry, Cell and Molecular Biology (BCMB)
Weill Graduate School of Medical Science of Cornell University, New York, NY, USA
(Affiliated with Memorial Sloan Kettering Cancer Center, New York, NY, USA)
Laboratory of Dr. Bryan M.F. Tsou, Memorial Sloan Kettering Cancer Center
- Thesis : Shape and copy number control of centriole duplication
2008-2009 : Professional Research Associates
Skirball Institute of Biomolecular Medicine, New York University Medical School. New York, NY, USA
Laboratory of Dr. Greg S. B. Suh
- Project: Identification of mosquito ortholog of Drosophila olfactory receptor IR64A
2007-2008 : Research Associates
School of Biological Sciences, Seoul National University, Seoul, South Korea
Laboratory of Dr. Yeonhee Choi, Seoul National University
2005-2007 : M.S. in Biological Sciences
School of Biological Sciences, Seoul National University, Seoul, South Korea
Laboratory of Dr. Yeonhee Choi, Seoul National University
- Thesis : Mitotic Epigenetic Inheritance of Meristematic DNA Demethylation
2000-2004 : B.S. in Biological Sciences
School of Biological Sciences
Seoul National University, Seoul, South Korea
2003 : Summer Semester in University of California, Berkeley, USA
Skills and Expertise
- Organoid culture
- Light Sheet Fluorescent Microscopy (LSFM)
- Super-resolution microscopy techniques :3D-Structured Illumination Microscopy (3D-SIM), Stochastic Transfer of Resonance Microscopy (STORM)
- Basic understanding of Stimulated Emission Depletion Microscopy (STED)
- CRISPR/Cas9 gene editing in human cells
- Adeno-associated virus-mediated homologous recombination in human somatic cells
- Basic understanding of human, yeast, Drosophila, and plant genetics
Publication
Kim, M., O’Rouke B.P., Soni, R. K., Jallepalli, P.V., Hendrickson, R., and Tsou, M.F. (2016) Promotion and suppression of centriole duplication are catalytically coupled through PLK4. Cell Rep 16(5):1195-1203
Fong, C.S., Mazo, G., Das, T., Goodman, J., Kim, M., O’Rouke B.P., Izquierdo, D., and Tsou, M.F. (2016) 53BP1 and USP28 mediated p53-dependent cell cycle arrest in response to centrosome loss and prolonged mitosis. Elife 2016;5:e16270
Kim, M., Fong, C.S. and Tsou, M.F. (2014) Centriole duplication: when PLK4 meets Ana2/STIL. Curr Biol 24(21):R1046-1048
Fong, C.S.*, Kim, M.*, Yang, T.T., Liao, J.C. and Tsou, M.F. (2014) SAS-6 assembly template by the lumen of cartwheel-less centriole precedes centriole duplication. Dev Cell 30(2):238-245
(* equal contribution)
Kim, M., Ohr, H., Lee, J., Hynn, Y., Fischer, R.L. and Choi, Y. (2008) Temporal and spatial downregulation of Arabidopsis MET1 activity results in global DNA hypomethylation and developmental defects. Molecules and Cells 26 (6):611-615